Erdem, FuatKiki, IlhamiGuendogdu, MehmetKaya, Hasan2024-09-182024-09-1820071011-7571https://doi.org/10.1159/000102159https://hdl.handle.net/20.500.12483/12561Objective: To report a case of brucella infection presenting with thrombotic thrombocytopenic purpura (TTP) that responded well to plasma and antimicrobial treatment infusion. Case Presentation and Intervention: A 51-year-old man with moderate confusion, depressed mood and dysarthria was admitted. He was chronically ill, with fever (38.5 degrees C), anemia, jaundice and petechial-purpuric skin lesions. Neurological examination revealed diminished consciousness with a Glasgow coma scale score of 7 and +1 neck rigidity. The hemoglobin and platelet counts were decreased and reticulocyte index, erythrocyte sedimentation rate, as well as serum lactate dehydrogenase and renal dysfunction were elevated. TTP was a possible diagnosis and the patient responded well to plasma infusion and antimicrobial treatment. Conclusion: This report shows that therapy of underlying infection together with plasma infusion may be a successful treatment option for brucellosis-induced TTP. Copyright (C) 2007 S. Karger AG, Basel.eninfo:eu-repo/semantics/openAccessthrombotic thrombocytopenic purpurabrucellosisantimicrobial treatmentArticle16432432610.1159/000102159175413022-s2.0-34249826349Q1WOS:000247028400014Q4