Özkan, HüseyinYakan, Akın2024-09-192024-09-1920201308-15942147-6853https://doi.org/10.30607/kvj.728554https://search.trdizin.gov.tr/tr/yayin/detay/447002https://hdl.handle.net/20.500.12483/15931In this study, the relationship between the expression levels of SCD, FASN, SREBPF1 genes and milk fatty acidprofiles in goat milks with low (LSFA) and high (HSFA) saturated fatty acid content was investigated andcorrelated. In HSFA group, SCD, FASN and SREBPF1 genes were approximately 7, 9 and 4 folds moreexpressed than LSFA in milk somatic cells, respectively (P<0.01). Also, positive correlations were determinedbetween SCD and FASN (0.907; P<0.001), SCD and SREBPF1 (0.628; P<0.001), FASN and SREBPF1 (0.720; P<0.001) genes. Positive and important correlation was found between C6:0 (Caproic acid) and SCD (0.468;P<0.05) and SREBPF1 (0.388; P<0.05) genes. On the other hand, positive correlations were found between all ofthese three genes and C8:0 (Capric acid) and C10:0 (Caprylic acid). In milk samples, C14:0 (Myristic acid) andSREBPF1 genes were correlated positively (0.469; P<0.05). Moreover, positive correlation was found betweenthe odour index and SCD (0.553; P<0.01), FASN (0.444; P<0.05), SREBPF1 (0.499, P<0.05) genes. The resultsshowed that SCD, FASN and SREBPF1 genes have important effects on the milk fatty acid profile and milkquality of goats and these genes may be candidate in selection applications in goats.eninfo:eu-repo/semantics/openAccessGoatGene expressionMilk fatty acidsSomatic cellsArticle13329430310.30607/kvj.728554447002