Seyfeli, E.Duru, M.Kuvandik, G.Kaya, H.Yalcin, F.2024-09-182024-09-1820060307-05651476-5497https://doi.org/10.1038/sj.ijo.0803233https://hdl.handle.net/20.500.12483/11925Objective: The aim of this study was to investigate the effect of obesity on dispersion of P-wave duration and QTc interval in obese women. Methods: Forty-two obese women (Body mass index (BMI) 4073 kg/m(2), mean age 4579 years) and compared age-matched (BMI 2271 kg/m(2), mean age 41 +/- 6 years) twenty-five non-obese women were included in our study. Maximum and minimum P-wave duration, P-wave dispersion (difference between the maximum and the minimum P-wave duration), maximum and minimum QTc interval, and QTc dispersion (the difference between the maximum and the minimum QTc interval) were measured from 12-lead ECG. ECG's were transferred to a personal computer via a scanner and then used for magnification of 400 times by Adobe Photoshop software. Results: There was significant difference in BMI (40 +/- 3 vs 22 +/- 1 kg/m(2), P < 0.001, respectively) between obese and non-obese women. Obese women had higher Max. P-wave duration (116711 vs 94714 ms, P < 0.001), P-wave dispersion (51715 vs 26711 ms, P < 0.001), Max. QTc interval (449738 vs 419730 ms, P < 0.001) and QTc dispersion ( 57723 vs 38715 ms, P < 0.001) compared to non-obese women. A significant correlation was found between BMI and Max. P-wave duration (r = 0.584, P < 0.001), P-wave dispersion (r = 0.621, P < 0.001), Max. QTc interval (r = 0.410, P < 0.001), and QTc dispersion (r = 0.429, P < 0.001). In the linear regression analysis, compared to co-morbidity factors such as age, hypertension, diabetes mellitus and smoking, there was significant association between only BMI and electrocardiographic values (P-wave and QTc dispersion). Conclusion: We concluded that obesity caused significant increase in P-wave and QTc dispersion. Therefore, obese women may not only be under the risk of ventricular arrhythmias, but also they may under the risk of atrial arrhythmias.eninfo:eu-repo/semantics/closedAccessP-wave dispersionQTc dispersionArticle30695796110.1038/sj.ijo.0803233164325442-s2.0-33744463875Q1WOS:000237862800012Q1