Yildiz, HasanKalipci, ErkanOztas, HaydarYildiz, Deniz2024-09-182024-09-1820190973-14821998-4138https://doi.org/10.4103/jcrt.JCRT_1319_16https://hdl.handle.net/20.500.12483/7321Aim: The effect of acetylsalicylic acid (ASA) on thiol levels was studied in a rat model of azaserine carcinogenesis. Materials and Methods: ASA and azaserine were applied to the animals to research changes in cellular sulfhydryl (-SH) content and variations in free and protein-bound molecules containing the -SH group. Such effects in rats injected with azaserine were investigated at low (200 ppm) and high (400 ppm) concentrations of ASA over a relatively short (6 months) and a relatively long (12 months) period. Results: Changes in the hepatic, pancreatic, and renal -SH contents were also determined. Conclusion: Compared to the other tissues studied, the liver contained the highest levels of both free and protein-bound -SH.eninfo:eu-repo/semantics/openAccessAcetylsalicylic acidazaserineratssulfhydryl contentArticle15123123610.4103/jcrt.JCRT_1319_16308807832-s2.0-85063200907Q3WOS:000461542500038Q4