Onur, HaticeAral, HaleArica, VefikBercem, GamzeUsta, MuratKasapcopur, Ozgur2024-09-182024-09-1820131687-92601687-9279https://doi.org/10.1155/2013/498581https://hdl.handle.net/20.500.12483/13606Objective. Anticyclic citrullinated peptide antibodies (anti-CCP) testing is useful in the diagnosis of rheumatoid arthritis (RA) with high specificity. Arthritis is a very common clinical manifestation in children with familialMediterranean fever (FMF). The aim of the study was to show the presence of anti-CCP antibodies in child individuals diagnosed with FMF. Material and Methods. The study groups comprised one hundred and twenty-six patients (126) diagnosed with FMF (female/male (n): 66/60) and 50 healthy controls (female/male (n): 25/25). Clinical and laboratory assessments of the FMF patients were performed during attack-free periods. Erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP), fibrinogen, and anti-CCP antibody levels were measured. Results. Anti-CCP was negative in healthy controls and also in all FMF patients. There was not a significant difference in anti-CCP between the patient and the control groups. Our study has shown that anti-CCP was correlated moderately with age (rs = 0.271; p = 0.0020), duration of illness (rs = 0.331; p < 0.0001), and colchicine therapy (rs = 0.259; p = 0.004). Conclusion. Our data show that anti-CCP antibodies are not associated with FMF. Anti-CCP does not have a priority for identifying FMF arthritis from the other inflammatory arthritis.eninfo:eu-repo/semantics/openAccessCitrullinated Peptide AntibodiesDiagnostic-AccuracyAutoantibodiesChildrenArticle201310.1155/2013/498581241065022-s2.0-84884849053Q2WOS:000214705300012N/A