Ustun, NilgunTok, FatihYagiz, Abdullah ErmanKizil, NurhanKorkmaz, InanKarazincir, SinemOkuyucu, Esra2024-09-182024-09-1820130894-91151537-7385https://doi.org/10.1097/PHM.0b013e31829b4d72https://hdl.handle.net/20.500.12483/8584Objective: The aim of this study was to compare the efficacy and the safety of ultrasound (US)-guided vs. blind steroid injections in patients with carpal tunnel syndrome (CTS). Design: This prospective randomized single-blind clinical trial included 46 patients with CTS (46 affected median nerves). The subjects were randomized-to either the US-guided or the blind injection group-before they received 40 mg of methylprednisolone. They were evaluated using the Boston Carpal Tunnel Questionnaire symptom/function at baseline and at 6 wks and 12 wks after injection, and the side effects were noted. Results: The symptom severity and functional status scores improved significantly in both groups at 6 wks after treatment, and these improvements persisted at 12 wks after treatment (all P < 0.05). The improvement in symptom severity scores in the US-guided group at 12 wks was higher than in the palpation-guided group (P < 0.05). Average time to symptom relief was shorter in the US-guided group (P < 0.05). There was no significant difference between the two groups in terms of side effects (P > 0.05). Conclusions: Although both US-guided and blind steroid injections were effective in reducing the symptoms of CTS and improving the function, an earlier onset/better improvement of symptom relief suggests that US-guided steroid injection may be more effective than are blind injections in CTS.eninfo:eu-repo/semantics/closedAccessCarpal Tunnel SyndromeUltrasound-GuidedInjectionArticle9211999100410.1097/PHM.0b013e31829b4d72238116172-s2.0-84887099527Q1WOS:000330375100006Q1