Akdag, M. ZulkufBilgin, M. HakkiDasdag, SuleymanTumer, Cemil2024-09-182024-09-1820071536-83781536-8386https://doi.org/10.1080/15368370701357866https://hdl.handle.net/20.500.12483/9748The purpose of this stud), is to investigate the possible effect of an extremely low frequency magnetic field (ELF-MF) on nitric oxide (NO) level. In this study, 27 male Sprague-Dawley rats were used. The rats were divided into three groups: two experimental and one control (sham-exposed). The first and second experimental group (n = 10) were exposed to 100 mu T and 500 mu T ELF-MF during 10 months, 2 h a day, respectively, and the third (n = 7) group was treated like an experimental group except for ELF-MF exposure in methacrylate boxes. After ELF-MF and sham exposure, serum nitrite levels were measured by Griess reaction. A significant reduction was observed in nitrite levels among the first and second experimental groups of rats and sham-exposed rats after exposure for 10 months, 2 h a day, to ELF-MF of 100 and 500 LT (p < 0.01). These results suggest that prolonged ELF-MF exposure at intensities of exposure limits, determined by ICNIRP for public and occupational, may reduce NO production probably affected by NO generation pathways.eninfo:eu-repo/semantics/closedAccessELF magnetic fieldsnitric oxideratsAlteration of nitric oxide production in rats exposed to a prolonged, extremely low-frequency magnetic fieldArticle2629910610.1080/15368370701357866176130372-s2.0-34547327588Q2WOS:000247722700003Q4