Akgul, FeritMclek, IsmetDuman, TaskinSeyfeli, ErgunSeydaliyeva, TunzaleYalcin, Fatih2024-09-182024-09-1820060001-6314https://doi.org/10.1111/j.1600-0404.2006.00662.xhttps://hdl.handle.net/20.500.12483/11263Objectives: To investigate the left (LV) and right ventricular (RV) function in multiple sclerosis (MS) using standard echocardiography and Doppler tissue imaging (DTI). Materials and methods: A total of 41 patients with definite MS and 32 healthy controls were included in the study. Results: LV end-systolic dimension was increased and LV ejection fraction was decreased in MS patients compared with controls (P < 0.05). LV end-diastolic dimension was increased in MS patients, however, did not reach significance. Among DTI parameters, mitral annular peak early diastolic velocity to peak late diastolic velocity ratio (Em/Am) was decreased in MS patients, but not reach statistical significance. No significant differences in tricuspid annular Em/Am ratio was found between MS patients and controls. A statistically significant increase of DTI derived LV myocardial performance index was found in MS patients as compared with controls. RV myocardial performance index showed a tendency to be increased in MS patients, however, did not reach significance. Conclusions: These findings suggest subclinical LV dysfunction and preserved RV function in patients with MS.eninfo:eu-repo/semantics/openAccessmultiple sclerosisventricular functiontissue dopplerArticle114211411810.1111/j.1600-0404.2006.00662.x168670342-s2.0-33745827432Q1WOS:000238881200007Q3