Motor, Vicdan KoksaldiCelikbas, Aysel KocagsulBaykam, NurcanGok, Sebnem ErenDokuzoguz, Basak2024-09-182024-09-1820121307-94412147-2939https://doi.org/10.4274/Vhd.54264https://hdl.handle.net/20.500.12483/8262Objective: The risk of transmitting hepatitis B virus has been reported to continue in the blood of people with loss of HBsAg after recovery from hepatitis B virus infection. The aim of the present study was to investigate the hepatitis B virus DNA in patients with loss HBsAg after recovery from hepatitis B virus infection by using polymerase chain reaction. Materials and Methods: Total 57 cases were evaluated. Hepatitis B virus DNA was detected in 19 (43.2%) of 44 patients with loss of HBsAg after acute hepatitis B virus infection, and in 2 (15.4%) of 13 cases who had natural immunity with positive antiHBs. Results: Infectivity continued in 21 (36.8%) cases. Hepatitis B virus DNA levels were detected between 4.6 x102 with 1x105 genome / mL in these serum samples. Conclusion: In our study, hepatitis B virus DNA can positive in patients with loss of HBsAg after hepatitis B virus infection have been shown. For this reason, antiHBc screening more reliable than HBsAg was thought in the selection of blood donors. It was thought that hepatitis B virus DNA testing with polymerase chain reaction is appropriate in serum and tissues of donors with positive hepatitis B virus serology in the organ transplantation practices.trinfo:eu-repo/semantics/openAccessBlood donorshepatitis Bpolymerase chain reactionArticle182475110.4274/Vhd.54264WOS:000217194500002N/A