Belgin, Ceren AktunaSerindere, Gözde2024-09-192024-09-1920212149-8571https://doi.org/10.30934/kusbed.836910https://search.trdizin.gov.tr/tr/yayin/detay/459639https://hdl.handle.net/20.500.12483/15957Objective: To compare the effectiveness of the manual and semi-automatic segmentation modules of the third-generation software used in computedtomography (CT) images in calculating frontal sinus (FS) and sphenoid sinus (SS) areas and volumes.Methods: CT images of 200 patients (96 female, 104 male) between the ages of 19 and 73 years (mean 37.38 ± 16.32 years) were randomly selected.Volume and area of FS and SS were segmented manually and semi-automatically using InVesalius 3.1.1 software (CTI, Campinas, São Paulo,Brazil).Results: There was a statistically significant difference was found the main SS area in manual mode and semi-automatic mode as 4.80 ± 1.86 $cm^2$ and 4.84 ± 1.83 $cm^2$, respectively. The main SS volumes were in manual mode and semi-automatic mode as 8.44 ± 3.55 $cm^3$and 9.62 ± 3.21 $cm^3$, respectively. The main FS volumes were in manual mode and semi-automatic mode as 5.32 ± 2.04 $cm^3$ and 6.65 ± 2.70 $cm^3$, respectively. There was a statistically significant difference was found between manual mode and semi-automatic mode in volume calculation (p<0.05).Conclusion: It was seen that the values measured in both segmentations are close to those presented in the mean literature data, however, whenusing the semi-automatic segmentation module, it should be ensured that the formations other than the structure to be evaluated are not included inthe measurement.eninfo:eu-repo/semantics/openAccessSemi-automatic segmentationManual segmentationsphenoid sinusfrontal sinuscomputed tomographyArticle7321622210.30934/kusbed.836910459639