Buyukkaya, EyupKarakas, Mehmet FatihKarakas, EsraAkcay, Adnan BurakTanboga, Ibrahim HalilKurt, MustafaSen, Nihat2024-09-182024-09-1820141076-02961938-2723https://doi.org/10.1177/1076029612459675https://hdl.handle.net/20.500.12483/11105Purpose: The aim of this study is to investigate the relationship between the criteria comprising metabolic syndrome (MS) and neutrophil-lymphocyte ratio (NLR), a simple and reliable indicator of inflammation. Method: Seventy patients with MS and 71 age- and sex-matched control participants were included. Patients were classified into 3 groups based on the number of MS criteria: group 1 (with 3 criteria), group 2 (with 4 criteria), and group 3 (with 5 criteria). The NLR was calculated from complete blood count. Results: Patients with MS had significantly higher NLR compared to the control group. Moreover, the group 3 patients had higher NLR than those in groups 2 and 1 (P = .008 and P = .078, respectively), whereas there was no difference between the patients meeting 3 and 4 MS criteria (P = .320). Besides, NLR increased as the severity of MS increased (r = .586, P < .001). The cutoff level for NLR with optimal sensitivity and specificity was calculated as 1.84. Serum glucose and high-sensitive C-reactive protein level were found to be independent predictors of an NLR value greater than 1.84. Conclusion: The present study indicated a significant correlation between the criteria of MS and inflammation on the basis of NLR. Furthermore, there an increase in NLR as the severity of MS increases.eninfo:eu-repo/semantics/openAccessmetabolic syndromeneutrophil-lymphocyte ratioinflammationArticle20215916310.1177/1076029612459675229923492-s2.0-84893491917Q2WOS:000331206300008Q3