Ilhan, NiluferIlhan, OzgurTuzcu, Esra AyhanDaglioglu, Mutlu CihanCoskun, MesutParlakfikirer, NihanKeskin, Ugurcan2024-09-182024-09-1820140277-37401536-4798https://doi.org/10.1097/ICO.0000000000000033https://hdl.handle.net/20.500.12483/9600Purpose:The aim of this study was to investigate the relationship between pathologic myopia and the dry eye syndrome.Methods:Forty-five patients with a spherical equivalence (SE) greater than -6.0 diopters (D) and an axial length (AL) >26.5 mm were assigned to the pathological myopia group (group 1). Forty-four healthy individuals were selected from subjects with emmetropia whose SE values ranged from -1.0 to +1.0 D (group 2). Ocular surface disease index (OSDI) scores of all the patients were determined. All the participants underwent the following: Schirmer 1 test without anesthesia, corneal staining, tear break-up time (TBUT), Schirmer 1 test with anesthesia, and AL measurement.Results:The mean age of group 1 and group 2 patients was 40.2 12.3 and 38.8 +/- 9.3 years. The mean values of SE, keratometry, and AL were -9.6 +/- 3.8 D, 43.9 +/- 1.1 D, and 27.4 +/- 0.6 mm in group 1 and -0.1 +/- 0.5 D, 42.3 +/- 1.4 D, and 23.0 +/- 0.2 mm in group 2. The mean values of the Schirmer 1 test without and with anesthesia were 14.4 +/- 6.1 and 9.5 +/- 4.5 mm in group 1 and 16.7 +/- 6.2 and 11.4 +/- 6.0 mm in group 2. The mean TBUT in group 1 was 7.2 +/- 3.4 seconds, whereas that in group 2 was 13.6 +/- 3.7 seconds. There was a significant difference between the groups in SE, keratometry, AL, TBUT, and OSDI scores (P < 0.001).Conclusions:Patients with pathologic myopia have lower TBUT scores and higher OSDI scores when compared with healthy individuals.eninfo:eu-repo/semantics/closedAccessdry eye syndromesmyopia degenerativetear function testsocular surface disease indexArticle33216917110.1097/ICO.0000000000000033243228012-s2.0-84892963362Q1WOS:000329903900012Q2