Akgün, Kadir BurakKorkmaz, İnanKaradağ, Mehmet2024-09-192024-09-1920231300-4115https://doi.org/10.14744/IGH.2023.44227https://search.trdizin.gov.tr/tr/yayin/detay/1178108https://hdl.handle.net/20.500.12483/15527Objective: Pulmonary thromboembolism (PTE) is a disease characterized by occlu- sion of the pulmonary artery and its branches by thrombus material as a result of stasis, hypercoagulability, and/or endothelial damage. Recent studies have focused on platelet (PLT) parameters, mortality of the disease, and its use as a diagnostic parameter. In particular, a significant relationship was found between high mean PLT volume (MPV) values and mortality and disease risk in the meta-analyses. The aim of our study is to examine the relationship between PLT parameters and the severity of radiological involvement. Material and Methods: The files of patients who were followed up with the diag- nosis of pulmonary thromboembolism between 2012 and 2021 were reviewed ret- rospectively. The patients were radiologically divided into 3 groups: (1) those with major branch involvement, (2) those with segmental branch involvement without ma- jor branch involvement, and (3) those with only subsegmental branch involvement. In addition, patients were examined in two separate groups according to whether there was more than 50% of involvement in the main branch radiologically and whether the right ventricle/left ventricle ratio was above 0.9 or not, radiologically. PLT, neutrophil, lymphocyte, platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio, MPV, plateletcrit (PCT), platelet distribution width (PDW), and PLT large cell ratio data in complete blood count measurements taken from patients at the time of diagnosis were also recorded. Results: There was a significant correlation between rising in PLR and occlusion in the major branch more than 50% (p=0.041). PLT, PDW, PCT, and neutrophil values differed radiologically according to the involvement of major, segment, and subseg- ment; however, subgroup analyses did not provide the linear difference that we ex- pected in our study.Conclusion: An increase in the PLR appears to be associated with radiological weight in pulmonary thromboembolism. We think that the relationship between PLT indices and radiological involvement should be supported by multicenter studies.eninfo:eu-repo/semantics/openAccessArticle371162110.14744/IGH.2023.442271178108