Melek, Ismet M.Duman, TaşkinGali, Edip2024-09-192024-09-1920041301-1375https://hdl.handle.net/20.500.12483/14804Patient groups at high risk with respect to cerebrovascular disease has a particular importance in terms of etiological and clinic evaluations. Sickle cell anemia has an important place in the etiology of patients who have had stroke before the age of 20. Among the risk factor of cerebrovascular diseases occurring during childhood, sickle cell anemia is the second important cause following the congenital heart diseases. The probability of a patient with sickle cell anemia to have cerebral infarction is 250 times higher when compared to those who don't have this disease at same age. Those who are born in Hatay forms the 17.49% of the all hemoglobinopathy cases reported in Turkey. In this study, the data on stroke obtained from 506 cases by hemoglobin electrophoresis since 1994 in Hatay, where 10.5% of the population is the carrier, was reported. Of the cases, 403 (79,6%), 99 (19,6%), 2 (0,4%) and 2 (0,4%) were HbSS, HbSS+Thalessemia, HbSD and HbSE, respectively. During a period of 10 year, 5 patients had stroke. Among them, the youngest one was 3 yr old while the oldest one was 15 yr old. The data on hemopatolgical parameters and on clinical and etiological were investigated. Being an autosomal recessive disease and arising from the mutation of hemoglobin beta gene, sickle cell anemia is considered to be a high risk factor for stroke besides the hematological features. In the regions where gene carriers are densely populated, studies on early diagnosis and monitoring appears to be highly important in the detection and prevention of childhood strokes.trinfo:eu-repo/semantics/closedAccessComplicationNeurologicRisk factorsSickle cell anemiaStrokeArticle1031211282-s2.0-13644251485N/A