Balcı, AliKarazincir, SinemSanguen, OezlemGali, EdipDaplan, TurgayCingiz, CihangirEgilmez, Ertugrul2024-09-182024-09-1820081305-3825https://hdl.handle.net/20.500.12483/12245PURPOSE The aim of this study was to evaluate the type and prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease. MATERIALS AND METHODS A total of 102 patients with sickle cell disease at the Center of Hemoglobinopathy of the Antakya State Hospital were screened for intra-abdominal abnormalities by abdominal ultrasonography (US). Eighty-four patients were homozygous or sickle-cell disease (S/S), and 18 patients were compound heterozygotes for sickle cell-beta thalassemia (S/beta(thal)). At the time of examination, 15.7% (16/102) of patients had undergone gone splenectomy, and 18.6% (19/102) of patients had undergone cholecystectomy. RESULTS The most frequent US findings (expressed as percentages of all patients) were hepatomegaly (71.6%), renal enlargement (30.4%), autosplenectomy (33.3%), cholelithiasis (30.4%) and splenomegaly (17.4%). A bright liver was identified in 6 patients (5.9%), an echogenic pancreas in 4 patients (3.9%), and pancreatic punctate echogenic foci were identified in 5 patients (4.9%). Medullary or diffusely increased renal echogenicity was observed in 16 patients (15.7%). Sonographic findings typical of renal papillary necrosis were observed in one patient with S/S. Periportal lymphadenopathy was detected in 10 (11.9%) of 84 patients of the S/S group, and 2 (11.1%) of 18 patients of S/beta(thal) group. CONCLUSION Abdominal ultrasonographic imaging of patients with sickle cell disease revealed a high prevalence of abdominal abnormalities, especially in solid organs.eninfo:eu-repo/semantics/closedAccesssickle cell diseaseultrasonographyabdomenliverkidneyArticle143133137188141342-s2.0-55149091549Q2WOS:000258776600006N/A