Yilmaz, ErdalÇek, ŞehribanMazlum, Yavuz2024-09-192024-09-1920091303-2712https://hdl.handle.net/20.500.12483/14763The present study was conducted to investigate the effects of Genesis (G, a commercial mixture of phytoestrogens) on growth, body composition and sex differentiation of Sharp tooth catfish Clarias gariepinus. Genesis is a commercially available product on USA and European markets used for menopausal complaints as an alternative medicine. Different concentrations (0 mg G 30 L -1, 210 mg G 30 L -1, 420 mg G 30 L -1, 630 mg G 30 L -1, 750 mg G 30 L -1 and 1500 mg G 30 L -1) of Genesis were administered by immersion of newly hatched larvae (averaging 2.27±0.12 mg) every 3 days for 30 days then immersion treatments were ceased and all groups reared in the same condition for the later 90 days, a total 120 days experimental period. At the end of the trial, specific growth rate of the females increased with the increasing concentration of Genesis up to 420 mg 30 L -1 (P<0.05), but different concentrations of Genesis did not affect the growth performance of males (P>0.05). The highest value of protein content (21.60%) was observed from the 420 mg G 30 L -1 group and found significantly different from the control and other groups (P<0.05). Also, lipid contents were significantly affected by the Genesis concentrations and the highest lipid contents were detected in the 210 mg G 30 L -1 (5.98%) and the 630 mg G 30 L -1 (6.66%) groups. Although among the dosages used in the present study, 1500 mg G 30 L -1 was the most effective dosage that ensured maximum female ratio (69.77%), the sex ratios observed for 0, 210, and 420 mg G 30 L -1 treatment groups were nearly the expected ratio of 1:1 (male: female). Therefore, it was concluded that usage of higher doses and treatment durations of Genesis could be more effective for all-female production of the Sharp tooth catfish population. © Central Fisheries Research Institute (CFRI) Trabzon, Turkey and Japan International Cooperation Agency (JICA).eninfo:eu-repo/semantics/closedAccessClarias gariepinusGenesisGrowthImmersionSex determinationArticle9133372-s2.0-78449266243Q2