Demircan, TulayKizilca, OzgurYilmaz, NuhZihni, CuneytKir, MustafaUnal, Nurettin2024-09-182024-09-1820210742-28221540-8175https://doi.org/10.1111/echo.14993https://hdl.handle.net/20.500.12483/7852Background/Aim Two-dimensional speckle-tracking echocardiography (2D-STE) is a novel method that allows the assessment of regional myocardial function. The aim of our study was to use 2D-STE to assess left ventricular deformation in patients with coarctation of the aorta (CoA). Methods In this prospective study, patients with CoA (n = 42) and healthy controls (n = 39) were recruited. Children with CoA who visited the outpatient clinic between 2013 and 2014 were included. The data were compared with those obtained from the sex- and age-matched controls. Results The mean age of the patients was 5.8 +/- 4.5 years. Global longitudinal strain based on all three apical views and total global strain values did not appear to be different between the patient and the control groups (P = .59, P = .51, P = .15, P = .38). Hypertension was detected in 14 (33.3%) patients with CoA. There were significant differences between the global longitudinal strain values of the normotensive CoA subgroup and the hypertensive CoA subgroup (P < .05). Conclusions In our study, we found that 2D-STE total strain analysis of patients with CoA was not different from comparative healthy controls. However, we determined that 2D-STE parameters were lower in the hypertensive CoA subgroup compared to the normotensive CoA subgroup.eninfo:eu-repo/semantics/openAccessaorta coarctationcongenital heart defectsHypertensionpediatric echocardiographystrainArticle38341041610.1111/echo.14993335760532-s2.0-85101001325Q3WOS:000617067000001Q4