Ilhan, NiluferDaglioglu, Mutlu CihanIlhan, OzgurCoskun, MesutTuzcu, Esra AyhanKahraman, HilalKeskin, Ugurcan2024-09-182024-09-1820150927-39481744-5078https://doi.org/10.3109/09273948.2014.921715https://hdl.handle.net/20.500.12483/7463Purpose: To investigate the neutrophil/lymphocyte ratio (NLR) as an indicator of inflammation in patients with age-related macular degeneration (AMD). Methods: Patients were evaluated by a review of records. The study included 81 patients with dry AMD (group 1), 84 patients with wet AMD (group 2), and 80 healthy age-and sex-matched controls (group 3). The NLR of the patients was obtained from the hospital laboratory archive and was measured by dividing the neutrophil count by the lymphocyte count. Results: A significant difference was found in NLR values between groups 1 and 2 (p = 0.017), groups 2 and 3 (p<0.001), and groups 1 and 3 (p<0.001). In correlation analyses, NLR was correlated positively with age (r = 0.22, p<0.001) and disease severity (r = 0.40, p<0.001). Conclusions: Patients with AMD have higher NLR compared with controls, and NLR correlates with disease severity. NLR may be used as a biomarker of inflammation in AMD.eninfo:eu-repo/semantics/closedAccessAge-related macular degenerationblindnessinflammationneutrophil/lymphocyte ratioretinal drusenArticle23428729010.3109/09273948.2014.921715249879272-s2.0-84939429475Q1WOS:000361333100005Q2