Oztas, Didem MelisBilen, Bukem TanorenSener, Leyla TurkerBeyaz, Metin OnurUlukan, Mustafa OzerUnal, OrcunUnlu, Mehmet Burcin2024-09-182024-09-1820210010-86501803-7712https://doi.org/10.33678/cor.2021.027https://hdl.handle.net/20.500.12483/7991Objective: In this paper, we examined the relationship between atherosclerotic plaque characteristics and symptomatic carotid artery disease. Material and methods: Twenty-two patients who underwent carotid endarterectomy were enrolled into the study. Thirteen patients were male and remaining 9 patients were female. The mean age was 60.2 +/- 9.6 years. The carotid artery stenosis ranged between 75% and 99%. Eight patients were asymptomatic and remaining 14 patients were symptomatic. Ten patients suffered stroke. One of them had recurrent transient ischemic attacks, 4 patients had dizziness, and one of them had amaurosis fugax. The extracted plaques were evaluated by scanning acoustic microscopy (SAM) and micro-computerized tomography (micro-CT). Results: Smaller acoustic impedance values that reveal collagen-rich plaque formation were detected in patients who had stroke, while higher acoustic impedance values that reveal calcium-rich plaque formation were detected in the asymptomatic patients' plaques. Conclusions: Determination of plaque characteristics with modern radiographic techniques, rather than relying on the degree of stenosis in patients with carotid artery disease, may be helpful to discriminate patients requiring intervention.eninfo:eu-repo/semantics/openAccessAtherosclerotic plaque characteristicsCarotid artery stenosisSymptomatic diseaseArticle63445946510.33678/cor.2021.027WOS:000694709000005N/A