Tp-e interval and Tp-e/QTc ratio are significantly Increased in patients with brain death
Accessinfo:eu-repo/semantics/openAccessAttribution-ShareAlike 3.0 United Stateshttp://creativecommons.org/licenses/by-sa/3.0/us/
AuthorDemirtaş, Abdullah Orhan
Urgun, Örsan Deniz
İçen, Yahya Kemal
MetadataShow full item record
CitationDemirtaş, A. O. (2019). Tp-e interval and Tp-e/QTc ratio are significantly increased in patients with brain death. Acta Medica, 50(3), 25-31.
Objective: We aimed to investigate whether there is a change in Tp-e interval, Tp-e/ QT and Tp-e/QTc ratios in patients with brain death. Materials and Methods: Fifty brain death patients and 50 age and sex matched healthy controls were included in the study. In addition to routine evaluation, Tp-e interval, Tp-e / QT and Tp-e / QTc ratios were measured in 12-lead electrocardiography. Tp-e was measured in the precordial leads using the Tail method; the time from the peak of the T wave to the point where the wave reached the isoelectric line. Results: White blood cell, aspartate aminotransferase, alanine aminotransferase and high sensitive c reactive protein levels were significantly higher in patients with brain death. The frequency of patients with QTc prolongation, Tp-e interval, Tp-e/QT and Tp-e/QTc values were significantly higher in patients with brain death (p <0.05). Tp-e interval, Tp-e/QT and Tp-e/QTc values were found to be positively correlated with HsCRP (p<0.001 for all). Conclusion: Tp-e interval, Tp-e / QT and Tp-e / QTc ratios are increased in patients with brain death compared to healthy controls. The mechanisms of this association and possible relationship with neuroendocrine changes should be investigated in future studies.
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