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dc.contributor.authorDuran, Nizami
dc.date.accessioned2019-07-16T15:47:58Z
dc.date.available2019-07-16T15:47:58Z
dc.date.issued2004
dc.identifier.issn1300-0144
dc.identifier.urihttps://trdizin.gov.tr/publication/paper/detail/TkRRMU9UQXc=
dc.identifier.urihttps://hdl.handle.net/20.500.12483/864
dc.description.abstractWe performed a serological evaluation of herpes simplex virus (HSV) infections at the time of labor. In order to determine the seroprevalence of asymptomatic HSV infections in pregnant women, blood samples were collected for antibody measurement from 130 randomly selected pregnant women. Presence of HSV IgG and IgM antibodies in the serum samples was tested by ELISA. The prevalence of HSV-1 gG1 antibodies was 90% (117/130), that of HSV-2 gG2 antibodies was 63.1% (82/130) and that of HSV-2 IgM antibodies was 13.8% (18/130). Eight (44.4%) of the pregnant women with HSV-2 IgM were at the same time found to have HSV-2 IgG antibodies, and 10 (55.6%) women were determined to have HSV-2 IgM antibodies. Furthermore, 6 (4.6%) out of the 130 pregnant women were seronegative for HSV. In conclusion, the results of our study show that the prevalence of HSV-2 infection (63.1%) is relatively high among asymptomatic pregnant women in Adana, Turkey. Therefore, to take precautions for reducing the risk of neonatal herpes, the investigation of HSV-2 type specific antibodies in pregnant women should be offered by using HSV-2 gG2 type specific serological tests that allow the identification of women with asymptomatic or subclinical genital HSV-2 infection and women susceptible to primary genital HSV-2 infection.en_US
dc.description.abstractWe performed a serological evaluation of herpes simplex virus (HSV) infections at the time of labor. In order to determine the seroprevalence of asymptomatic HSV infections in pregnant women, blood samples were collected for antibody measurement from 130 randomly selected pregnant women. Presence of HSV IgG and IgM antibodies in the serum samples was tested by ELISA. The prevalence of HSV-1 gG1 antibodies was 90% (117/130), that of HSV-2 gG2 antibodies was 63.1% (82/130) and that of HSV-2 IgM antibodies was 13.8% (18/130). Eight (44.4%) of the pregnant women with HSV-2 IgM were at the same time found to have HSV-2 IgG antibodies, and 10 (55.6%) women were determined to have HSV-2 IgM antibodies. Furthermore, 6 (4.6%) out of the 130 pregnant women were seronegative for HSV. In conclusion, the results of our study show that the prevalence of HSV-2 infection (63.1%) is relatively high among asymptomatic pregnant women in Adana, Turkey. Therefore, to take precautions for reducing the risk of neonatal herpes, the investigation of HSV-2 type specific antibodies in pregnant women should be offered by using HSV-2 gG2 type specific serological tests that allow the identification of women with asymptomatic or subclinical genital HSV-2 infection and women susceptible to primary genital HSV-2 infection.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.titleSerological evaluation of HSV-1 and HSV-2 infection in pregnancyen_US
dc.typearticleen_US
dc.relation.journalTurkish Journal of Medical Sciencesen_US
dc.contributor.departmentHatay Mustafa Kemal Üniversitesien_US
dc.identifier.volume34en_US
dc.identifier.issue2en_US
dc.identifier.startpage97en_US
dc.identifier.endpage101en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]


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