Asymmetric septal hypertrophy with perimembranous septal defect and obstructive right ventricular outflow tract in a patient with hypertrophic cardiomyopathy

Abstract

The previous echocardiographic studies have estimated the prevalence of hypertrophic cardiomyopathy (HCM) in the general population to be 0.2% (1). Asymmetric hypertrophy of the left ventricle, predominantly of the septum and anterior wall of the left ventricle, is present in 70 % of patients with HCM. However, right ventricular outflow obstruction with the left ventricular outflow tract intact is a very rare pathology (2). In addition, certain congenital cardiac malformations have been reported in patients with asymmetric septal hypertrophy (ASH) (3). To our knowledge, there are no studies and case reports, which show association between obstructive right ventricular hypertrophy and ASH with perimembranous ventricular septal defect (VSD). We present an ASH case with perimembranous septal defect and obstructive right ventricular hypertrophy.