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    Conjunctival Impression Cytology and Tear Function in Patients with Keratoconus
    (2021) Özcan, Deniz Özarslan; Özcan, Sait Coşkun; Gürsoy, Didar
    Objectives: The aim of this study was to evaluate the ocular surface alterations of conjunctival cytological changes and tear function in patients with keratoconus. Methods: A total of 98 eyes with keratoconus and 68 eyes of age- and sex- matched healthy subjects were included in this prospective study. Ophthalmological evaluations, including Ocular Surface Disease Index (OSDI), tear break-up time (TBUT), ocular surface staining (OSS), Schirmer test, and conjunctival impression cytology (CIC), were performed. Results: The mean participant age was 23.4±5.3 years in the keratoconus group and 24.9±6.0 years in the control group. In the keratoconus group, the mean OSDI and OSS scores were statistically significantly higher than those of the controls, and the Schirmer and TBUT results were statistically significantly lower (all p<0.001). The severity of keratoconus was positively correlated with the CIC grade (r=0.292; p=0.004). Conclusion: Keratoconus results in deterioration of the ocular surface, including CIC and tear function parameters. The grade of keratoconus appears to be associated with conjunctival cytologic changes.
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    Epidemiological and Clinical Characteristics of Childhood Open Eye Injuries in the South of Anatolia
    (2021) Cakmak, Ayse Idil; Kakaç, Ahmet; Khaleqı, Zikria; Cankurtaran, Veysel; Özcan, Sait Coşkun; Elbeyli, Ahmet; Çetin, Şirin
    Purpose: The aim of this study is to determine the demographic, epidemiological and etiological characteristics of pediatric patients presented\rwith open eye injury (OEI).\rMaterials and Methods: We retrospectively reviewed medical records of the children who presented with OEI to a tertiary eye care center\rbetween January, 2017 and July, 2019. The cases were stratified into two groups as preschool (2-5years) and school-age (6-16years) children.\rResults: The study included 39 eyes of 37 cases. The mean age was 7.38±4.01 years and male: female ratio was 1.85. The study included 22\reyes of 22 preschool and 17 eyes of 15 school-age children. It was seen that the most common OEIs were OEI by a sharp object (25 cases;\r64.1%), penetrating OEI (35 cases; 89,7%), zone I OEI (19 cases; 48.7%), corneoscleral OEI (19 cases; 48.7)) and small OEI (<5 mm in size)\r(18 cases;46,2%). Intraocular foreign body was detected in 5 cases (12.8%). No significant relationship was found between lens damage and\rcause of trauma (p=0.427); whereas there was a significant correlation between size of injury and retinal detachment (p<0.0001 for both). It was\rfound that there was bilateral OEI in 2 of 5 cases injured during the Syrian civil war and that 3 cases underwent evisceration.\rConclusion: Unlike the children who were seriously injured in the war environment, it was determined that children in peace environment were\rexposed to OEI with milder symptoms, mostly by preventable reasons. The results of this study show the severe effects of war on children; in\raddition, it may help to raise awareness and take first steps for prevention of OEI in children in peace.\rKeywords: Eye injuries, open-globe injury, trauma.
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    Results of dominant and non-dominant hand phacoemulsification
    (S.B. Haseki Eğitim ve Araştırma Hastanesi, 2019) Özcan, Sait Coşkun; Kavşut, Bilal; Tunçbilek, Zehra; Solmaz, Nilgün; Önder, Feyza
    Aim: The aim was to present the outcomes of phacoemulsification surgery with dominant and non-dominant hands. Methods: Eighty eyes of 72 patients undergoing phacoemulsification with a temporal clear corneal incision were included in the study by reviewing their medical records and were divided into two groups. Forty of operated eyes were right eyes and forty were left ones. We operated right eyes with dominant (right) hand, and left eyes with non-dominant (left) hand through a temporal clear corneal tunnel. The patients were followed up at week 1 st and month 1 st and 3rd. Keratometry and specular microscopy were performed preoperatively, at month 1 st and 3rd after surgery. We recorded the total volume of fluid used, phaco time and cumulative dissipated energy. We calculated surgically-induced astigmatism using vector analysis. Results: There was no statistically significant difference in intraoperative and postoperative outcomes between phacoemulsification surgeries performed with dominant and non-dominant hands. Conclusion: Phacoemulsification surgeries can be carried out with non-dominant hand and with excellent outcomes.
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    Safety and Efficacy of Corneal Crosslinking Treatment in Children with Keratoconus
    (2021) Özcan, Deniz Özarslan; Özcan, Sait Coşkun
    Background: To evaluate the safety and efficacy of corneal crosslinking (CXL) treatment in children with keratoconus. Materials and Methods: A total of 45 eyes of 34 children with progressive keratoconus were included in this study. CXL was performed according to the conventional method. Manifest refraction, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corneal topography values, and endothelial cell density (ECD) were evaluated at baseline and 24- month follow-up. Results: The mean age of the patients was 14.6±3.5 years. The mean spherical equivalent readings were statistically significantly decreased at 24 months (p=0.016). There was a significant improvement in the mean UDVA and CDVA at 24 months (p=0.002, p=0.006, respectively). The mean K1 and K2 were statistically significantly reduced at 24 months postoperatively (p=0.004, p=0.006, respectively). There was no significant alteration in ECD at any follow-up examination. No significant sight-threatening complications were observed. Conclusions: The CXL procedure seem to be safe and effective in stabilizing keratoconus progression in children within a follow-up of 24 months.