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    The presence of the tender points in female patients with hepatitis C virus infection: Is it related with the clinical findings of fibromyalgia?: A preliminary report
    (Turkiye Klinikleri, 2006) Kandemir, Özlem; Şahin, Günşah; Güler, Hayal; Şahin, Elif
    Objective: Fibromyalgia (FM) may be related with hepatitis C virus (HCV) infection. Tender points are also the hallmark of the FM and may be precipitated by infection. We planned a study to determine if HCV infection is associated with the development of tender points, which are the diagnostic hallmark of FM. Material and Methods: A total of 40 female subjects diagnosed as having HCV infection were assessed by physical examinations (palpation of 18 tender points) and laboratory tests. In addition, visual analogue scale (VAS) for pain assessment was performed for all subjects. Patients were compared with age and sex matched FM patients [diagnosed by American College of Rheumatology (ACR) criteria] and healthy controls. Results: There was a statistically significant difference between patients with HCV infection and FM patients regarding tender points (p< 0.01). Patients with HCV infection had lower counts of tender points than FM patients had. Tender points were also lower in controls. In addition, VAS score was significantly different in all groups (p< 0.01). FM patients had the highest VAS score. Conclusions: Patients with HCV infection did not meet FM criteria in terms of tender points. Tender points, which are diagnostic for FM, are not a common finding in HCV infection. As a result, we may suggest that HCV infection may not be related with FM and its etiopathogenesis. Copyright © 2006 by Türkiye Klinikleri.