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Öğe Family functioning and its clinical correlates in overweight and obese patients(Editrice Kurtis S R L, 2011) Bez, Y.; Ari, M.; Gokce, C.; Celik, M.; Kaya, H.AIM: Our aim is to evaluate the differences in family functioning and anxiety between normal, overweight, and obese subjects. METHOD: Overweight and obese patients were selected from the outpatient clinic of internal medicine department of a university hospital. Patients were classified into three groups as normal weight (N=82), overweight (N=33) and obese (N=50) patients. The normal weight group included healthy subjects. The individuals were examined by the same psychiatrist (MA). Beck Anxiety Inventory and Family Assessment Device were applied to all groups. RESULTS: When compared to normal weight patients, obese and overweight patients had significantly higher anxiety scores and higher scores in general functions, problem solving, communication, roles, affective responsiveness, and behavior control dimensions which reflect increased dysfunctions in their families. The total level of dysfunction that patients experience was predicted by alcohol dependence in the family during childhood period, any medical disorder in the current family, anxiety level and body mass index. CONCLUSION: When treating them clinicians should keep in mind that families of obese and overweight patients may have higher levels of dysfunctions. (Eating Weight Disord. 16: e257-e262, 2011). (C)2011, Editrice KurtisÖğe Plasma nesfatin 1 level in patients with first attack psychosis(Comenius Univ, 2017) Sahpolat, M.; Ari, M.OBJECTIVES: This study aimed to investigate the possible relationship between plasma concentrations of nesfatin 1 and first attack psychosis. METHODS: Totally, 32 patients with the first episode psychosis and 33 randomly selected weight- and body mass index-matched healthy volunteers admitted to Mustafa Kemal University, Faculty of Medicine, Training and Research Hospital, Psychiatry outpatient clinic were included. Healthy control subjects were matched in terms of weight and body mass index (BMI). The Positive and Negative Syndrome Scale (PANNS) was applied to the patient group. The enzyme-linked immunosorbent assay (ELISA) method was used to measure plasma nesfatin 1 levels. RESULTS: The mean nesfatin 1 level was lower in the patients with the first attack psychosis (0.60 +/- 1.00 ng/mL) than in the control group (0.75 +/- 1.07 ng/mL).However it did not reach statistical significance (t = 0.567, p = 0.573). There was no statistically significant correlation between plasma nesfatin 1 levels and total PANNS scores in the patient group (r = 0.262, p = 0.148). CONCLUSION: Our study was the first to investigate the nesfatin 1 levels in patients with the first episode psychosis. Based on our study results, nesfatin 1 might be related to some central nervous system pathologies, including the severity of a psychiatric disorder; however, further large-scale studies are required to establish a conclusion (Tab. 1, Ref. 21). Text in PDF www.elis.sk.