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Öğe A 5-year retrospective evaluation of snakebite cases in Hatay, Turkey(Sage Publications Inc, 2015) Karakus, Ali; Zeren, Cem; Celik, M. Murat; Arica, Secil; Ozden, Raif; Duru, Mehmet; Tasin, VeyisSnakebites are relatively rare medical emergency cases that might lead to serious consequences. This study aims to evaluate snakebite cases in terms of medical follow-up, antivenom therapy and antivenom reactions. Medical records of patients admitted to emergency department between January 1, 2006 and December 31, 2010 were retrospectively investigated. Snakebite-related cases of a total of 125 patients were included in the scope of the study. Of the total 125 cases, 54.4% were male and 45.6% were female. Most of cases (n: 65, 52%) were aged over 30years, while the mean age was 34.87 +/- 19.29years. Snakebite-related applications to the emergency department were mostly seen in June with 27 cases. Upon admitting, all patients were recorded to be conscious and showing good general conditions; however, they suffered from pain and edema at the site of bite. Of all, 25 patients only suffered from bite injury and ecchymosis due to snakebite. The site of bite was upper extremities in 66 patients (52.8%), whereas it was lower extremities in 58 (46.4%). Of all, antivenom was unnecessary in 25 (20%) patients, while four antivenoms were administered to each of the 23 (18.4%) patients. Furthermore, six (4.8%) patients needed nine antivenom administrations for each. Anaphylaxis (n: 2, 1.6%), compartment syndrome (n: 2, 1.6%) and serum sickness (n: 1, 0.8%) encountered in remaining cases. Of all, 86 (68.8%) patients were hospitalized in the emergency department, while 25 (20.0%) patients were followed up by observation in emergency service. Only one patient was treated and followed up in intensive care unit. Implementation of antivenom therapy is considered unnecessary for the treatment of all snakebite cases. Antivenom reactions and number of related cases might be reduced by continuous close monitoring, appropriate prophylaxis and controlled slow infusion administration of medications.Öğe Acute Atrial Fibrillation and Anaphylaxis due to Bee Sting: Case Report(Aves, 2014) Karakus, Ali; Akcay, A. Burak; Celik, M. Murat; Arica, Secil; Tasin, Veyis; Caliskan, KocaIntroduction: Reactions due to bee stings ranging from local reactions to anaphylactic shock may occur in clinical presentations. Cardiac side effects and death may occur as a result of bee stings. Case Report: This study described a 53-year-old man with no history of cardiac disorders or anaphylaxis whose lip was stung by a bee. The patient was brought to the emergency department with anaphylactic shock. There was acute atrial fibrillation shown on the electrocardiogram, and echocardiogram and biochemical markers were normal. Conclusion: In the literature, three patients developed atrial fibrillation and atrial flutter as a result of bee stings. We also aim to share the diagnosis and treatment of such a case.Öğe Analysis of Assumed Violence Exposed Pediatric Cases(Derman Medical Publ, 2012) Arica, Vefik; Tutanc, Murat; Arm, Mustafa; Arica, Secil; Turhan, Ebru; Zeren, Cem; Arslan, MustafaAim: Violence against children is among one of the major problems encountered in family health practice. In this study, we aimed to analyze the demographic features of children who what exposed to violence and the types of violence exposed. Material and Method: Records of children who have administered to Hatay Child Police Department among 2005-2008 withcomplaint of violence exposure have been retrospectively analyzed. Results: Pediatric cases were analyzed according to their age, gender and the type of violence that they have benne exposed. The number of children that present with violence exposure was 156 while it raised to 597 with an increase of approximately 382%. 1577 cases presented during study period and 732 cases were male and 845 of them were female. We detected that male children between 0-12 years old age were more prone to violence exerted by family members as physical violence and wounding. Female children were exposed to more sexual violence and suicide while male children were exposed to physical violence.Discussion: We detected in this study that violence exerted to children show differences according to age and gender. It has been suggested that the number of children exposed to violence is much more higher than the reported number if we include economic and emotional abuse. Violence against children is an important issue that should be carefully addressed.Öğe The Analysis of Mean Platelet Volume and Platelet Distribution Width Levels in Appendicitis(Springer India, 2015) Aydogan, Akin; Akkucuk, Seckin; Arica, Secil; Motor, Sedat; Karakus, Ali; Ozkan, Orhan Veli; Yetim, IbrahimWe aimed to analyze the diagnostic value of mean platelet volume and platelet distribution width, which are also known as the markers of platelet count, in acute and perforated appendicitis. The data of 202 patients who applied to general surgery clinic in Mustafa Kemal University Hospital from 2007 to 2012 with acute appendicitis were analyzed retrospectively. The findings were separated to two groups due to the perforation status (perforated vs. non-perforated). Age, sex, leukocyte, hemoglobin, hematocrit, mean platelet volume, and platelet distribution width were examined. The mean age of the patients was 35.8. Twenty-one of all cases were perforated appendicitis (10.4 %), and the rest was acute appendicitis (non-perforated) (n=181, 89.6 %). The mean platelet volume value was 9.8 +/- 2.1 fL; mean thrombocyte count, 340.9x10(9)/L; and mean platelet distribution width value, 18.3 %. There were statistically significant differences between sex and age, hemoglobin, hematocrit, leukocyte, mean platelet volume, and platelet distribution width. There was a positive correlation between mean platelet volume, platelet distribution width, and platelet. Age, leukocyte, platelet, mean platelet volume, and platelet distribution width were higher in cases with perforation as a comparison with non-perforated cases. We think that mean platelet volume and platelet distribution width may be valuable markers to detect the risk of perforation in early periods of acute appendicitis.Öğe Convulsion in infants as a result of oral use of garden sage(Galenos Yayincilik, 2012) Arica, Vefik; Arica, Secil; Tutanc, Murat; Motor, Sedat; Motor, Vicdan Koksaldi; Dogan, MuratSalvia officinalis is a plant known as Garden Sage and it is used by the community in case of various clinical conditions. Herbalists are the right destinations to provide this special plant. Salvia officinalis is known to be used for its diuretic, anti-inflammatory, antimicrobial, antiseptic, expectorant, spasmolytic and diaphoretic effects. In this case study, a case of intoxication in which a 2-month old infant who presented with convulsion due to accidental oral use of garden sage oil which was actually prepared for topical use by a herbalist is reported. (Turk Arch Ped 2012; 47:67-8)Öğe Daily and every other day use of iron prophylaxis in the first year of life(Galenos Yayincilik, 2010) Arica, Vefik; Arica, Secil; Tutanc, Murat; Motor, Sedat; Onur, Hatice; Dogan, MuratAim: In countries like Turkey where iron deficiency anemia (IDA) is common, it was that iron prophylaxis can be used every other day as intermittent because it would show the same effect and easier for compliance. Material and Method: Two groups of infants born healthy, breastfed exclusively for the first six months and given 400 IU vitamin D were included in the study. In the fourth month of their life, infants started to take iron (Fe +2) 1 mg/kg/day and the second group 2 mg/kg/48 h In use of daily 1 mg/kg/day dose as of the fourth month till the first year 75 patients (the first group), in use of 2 mg/kg/48 h 80 patients (the second group) were involved in our study group. 34 infants (the third group) who did not start to take iron prophylaxis or use any was taken in our study as a control group. Results: It was found out that in the first group 14 infants (18.6%) developed iron deficiency (ID), 3 infants (4%) iron deficiency anemia (IDA), in the second group 16 infants (20%) developed ID and 4 infants (5%) IDA, in the third group, namely in the control group 12 infants (35,3%) developed ID and 10 infants (29.4%) IDA. In comparison of the control group with the first and second groups, IDA portion was less in iron prophylaxis groups, this value was found statistically reliable (p=0.001). When the first and second groups were compared with one another, a statistical difference could not be found between ID/IDA proportions. Because ID and IDA were encountered in both prophylaxis groups it was assumed that iron prophylaxis given just during the first year of life should also be given afterwards. Conclusions: There is no statistical difference between the first and second prophylaxis groups, thus, it was considered that instead of daily use, taking iron every other day would be more effective when it was given in a proper dose. (Turk Arch Ped 2010; 45: 343-7)Öğe Development of acute dystonia in three brothers due to metoclopramide(Isfahan Univ Med Sciences, 2012) Silfeler, Ibrahim; Arica, Vefik; Arica, Secil; Dogan, MuratOne of the agents that cause dystonic reactions is metoclopramide. In this study, we presented three individuals of the same family who were admitted to our hospital while receiving the treatment of metoclopramide because of developing acute dystonic reaction. Appropriate doses of metoclopramide therapy had begun to all brothers with a diagnosis of gastroenteritis. After receiving the first dose of medication, acute dystonia was observed within half an hour in these brothers who used metoclopramide. Thus, if there is a patient who developed acute dystonia in the same family due to metoclopramide, avoiding from use of metoclopramide will be beneficial for other members of the family.Öğe Dual effects of erdosteine on hemostasis via its different metabolites in young rats(Sage Publications Ltd, 2011) Arica, Vefik; Tutanc, Murat; Ozturk, Oktay Hasan; Arica, Secil; Basarslan, Fatmagul; Erden, Ersin Sukru; Oktar, SuleymanAim: In the study, we examined erdosteine's effects on platelet functions and coagulation. Materials and methods: A total 29 young albino Wistar rats were divided into four groups. Control rats (n = 6) were given saline; Group I rats (n = 7) were given 3 mg/kg erdosteine by oral gavage for 3 days; Group 2 rats (n = 7) were given 10 mg/kg erdosteine by oral gavage for 3 days; and Group 3 rats (n = 9) were given 30 mg/kg erdosteine for 3 days. Twenty-four hours after the final dose, blood samples were drawn from a portal vein. Prothrombin time (PT), activated partial thromboplastin time (aPTT) and international normalized ratio (INR) were measured, and platelet counts were examined in a peripheral blood smear by light microscopy. Results: PT and INR values of Group I increased compared to the controls but did not change in Group 3. Hemostatic parameters were not measured in Group 2 because the blood samples in Group 2's tubes clotted rapidly. Platelet counts of the peripheral blood from Group 2 were low but were normal in other groups. Conclusion: We have concluded erdosteine may disrupt hemostasis parameters by its different metabolites in patients. Erdosteine has dual effects on hemostasis via its different metabolites, which occur in different doses.Öğe Evaluation of Mean Platelet Volume values in lean women with polycystic ovary syndrome(Professional Medical Publications, 2014) Silfeler, Dilek Benk; Kurt, Raziye Keskin; Yengil, Erhan; Un, Burak; Arica, Secil; Baloglu, AliObjective: Mean Platelet Volume (MPV) is an important indicator of platelet activation. It is known that MPV increases in patients with coronory artery disease, diabetes mellitus, atherosclerosis and Polycystic ovary syndrome (PCOS). Our aim was to measure the MPV in lean patients with polycystic ovary syndrome. Methods: The present study was designed to examine the platelet function by measuring MPV in non-obese women with PCOS. A total of 50 outpatients with PCOS were included. The control group consisted of 50 healthy subjects. Serum platelet, MPV, and white blood cell (WBC) levels were compared and evaluated retrospectively in all participants. These values were compared by statistical analysis. Results: There were no statistically significant difference in between groups regarding MPV (p=0.357), WBC (p=0.414) and platelet (p=0.666). Conclusion: There are studies implying MPV increase in PCOS patients, in our patients MPV levels did not correlate with PCOS except for patients with obesity. We think that PCOS itself has no effect on MPV levels and obesity changes MPV levels.Öğe Evaluation of the mean platelet volume in children with familial Mediterranean fever(Springer Heidelberg, 2012) Arica, Secil; Ozer, Cahit; Arica, Vefik; Karakus, Ali; Celik, Tanju; Gunesacar, RamazanTo evaluate the Mean Platelet Volume (MPV) levels in children diagnosed with familial Mediterranean fever (FMF), during attack and attack-free periods. The records of a total of 117 children with FMF, diagnosed using the Tel-Hashomer criteria, have been scanned. The study consisted of 53 patients during an attack (group 1), 64 patients in attack-free period (group 2), and 57 healthy controls (group 3). Erythrocyte sedimentation rate, C-reactive protein, white blood cell count, platelet count, and MPV levels were retrospectively recorded. The MPV and platelet values in FMF patients during attack (group 1) and FMF patients during attack-free periods (group 2) have been found to be significantly higher than those of the health control group (group 3). Positive correlation has been found between the MPV and platelet values in Group 1 and the disease's severity score (r = 0.224, and r = 0.268, respectively). Positive correlation (r = 0.528, and r = 0.485, respectively) has been also identified between MPV and blood platelet count in patients in Group 1 and 2. No correlation was found between the Colchicine treatment period and MPV (r = -0.005). The MPV values in the complete group of FMF diagnosed children have been found to be much higher compared to those in healthy children. As a consequence, we consider the MPV value as a useful marker that demonstrates the risk of early stage atherosclerosis in children with FMF.Öğe Investigation of Parvovirus B19 Seroprevalence, Endothelin-1 Synthesis, and Nitric Oxide Levels in the Etiology of Essential Hypertension(Taylor & Francis Inc, 2012) Motor, Vicdan Koksaldi; Arica, Secil; Motor, Sedat; Yilmaz, Nigar; Evirgen, Omer; Inci, Melek; Gokce, CumaliBackground and Aims: Many studies have focused on the role of pathogen infection in hypertension (HT). It has been postulated that increased vascular tonus in HT is basically related to the imbalance between vasodilator, such as nitric oxide (NO), and vasoconstrictor, such as endothelin-1 (ET-1), substances secreted by endothelium. The aim of the present study was to investigate the seroprevalence of human parvovirus B19 (HPV B19) in the etiology of essential HT and the effect of HPV B19 on ET-1 and NO levels in this disorder. Materials and Methods: A total of 135 participants were enrolled in the study (90 patient and 45 controls). Antibodies to HPV B19 and ET-1 were measured by enzyme-linked immunosorbent assay method. Nitric oxide levels were calculated according to the Griess reaction. Results: Of the total participants, 27 patients (30%) and 7 control subjects (15.6%) had IgM positive (P = .068), whereas 27 patients (30%) and 14 control subjects (31.1%) had IgG positive (P = .895). There was no statistical difference between patients and control subjects in terms of serum ET-1 and NO levels. Conclusions: The role of HPV B19 in the etiology of essential HT was not shown in the present study. A larger sample may be needed for the investigation of these relations.Öğe Level of serum 25-OHD in healthy children aged 0-36 months in Van(Turkish Pediatrics Assoc, 2010) Arica, Vefik; Arica, Secil; Gucuk, Sebahat; Edima, TamerAim: In recent studies, it has been shown that prevalence of rachitism and vitamin D deficiency depend on regional differences such as climate, socioeconomic level and changing benefits of people from health services. Even if no clinical symptom has occurred, serum 25-hydroxy D (25-OHD) level, which is the best indicator of vitamin D can be found low. Material and Method: In this study, serum 25-OHD levels of 112 healthy children, aging 0-36 months, who applied to the outpatient clinic of the Pediatrics and Gynecology Hospital for a routine control in Van, were analyzed. Nutrition style of mothers and their babies, duration of exposing to sunlight and taken vitamin supplements, were evaluated. Serum Ca, P, alkaline phosphatase and 25-OHD levels were studied and the left wrist x-rays were obtained. Abdominal ultrasonography was performed only the babies with serum 25-OHD level >150 ng/mL. Results: In our study, despite no clinical symptoms of rachitism regardless of gender, 25-OHD level <40 ng/mL was determined in 53.5% of the children and in %13,3 of these childrens serum level of 25-OHD was as low as <5 ng/mL, and suffering from heavy vitamin D deficieny. Conclusions: The breast-fed babies with no vitamin supplement did not show any sign of vitamin deficiency, but in 25-OHD levels were significantly low compared to the breast-fed babies with vitamin supplement. (Turk Arch Ped 2010; 45: 286-90)Öğe Malondialdehyde Level in the Cord Blood of Newborn Infants(Iranian Scientific Society Medical Entomology, 2011) Gulbayzar, Sayat; Arica, Vefik; Hatipoglu, Sami; Kaya, Aysem; Arica, Secil; Karatekin, GunerObjective: In this study, we aim to demonstrate that measurement of the malondialdehyde (MDA) level in the umbilical cord blood of newborn infants born via cesarean section (C/S) and normal vaginal delivery (NVD) is indicative of oxidative stress during the perinatal period. Methods: The study was conducted at Bakirkoy Training and Research Hospital between January 2006 and April 2006 on 15 newborns born via elective C/S, 15 newborns born via emergency C/S, and 15 newborns born via normal vaginal delivery. Complete blood count, total bilirubin, glucose, creatinine phosphokinase (CPK), uric acid, iron, blood gas, and malondialdehyde levels were measured in the umbilical cord blood Findings: Malondialdehyde levels in the umbilical cord blood in the emergency C/S and NVD groups were found to be statistically and significantly higher than those in the elective C/S group. In the emergency C/S group, it was determined that the malondialdehyde level increased as the oxygen saturation of the umbilical cord blood increased. In the NVD group, a positive correlation was detected between the total bilirubin and malondialdehyde levels in the umbilical cord blood. In the emergency C/S group, the malondialdehyde level was recorded to be high in the infants with high level of uric acid in the umbilical cord blood. Conclusion: We concluded that the malondialdehyde level in umbilical cord blood could serve as an indication of perinatal oxidative stress and that it could thus help in preventing permanent damage.Öğe Mean platelet volume is influenced by many inflammatory and cardiovascular disorders and cardiovascular risk factors(Springer, 2013) Tuzcu, Esra Ayhan; Arica, Secil; Ilhan, Nilufer; Daglioglu, Mutlu; Coskun, Mesut; Ilhan, Ozgur; Ustun, Ihsan[Abstract Not Available]Öğe Mean platelet volume measurement protocol should be standardized for diabetic retinopathy(Springer, 2013) Tuzcu, Esra Ayhan; Arica, Secil; Ilhan, Nilufer; Daglioglu, Mutlu; Coskun, Mesut; Ilhan, Ozgur; Ustun, Ihsan[Abstract Not Available]Öğe THE PREVALENCE OF URINARY INCONTINENCE, SEXUAL DYSFUNCTION AND QUALITY OF LIFE IN WOMEN OF REPRODUCTIVE AGE ADMITTED TO UROGYNECOLOGY DEPARTMENTS(Carbone Editore, 2014) Akkoca, Ayse Neslin; Kurt, Raziye; Ozdemir, Zeynep Tuba; Yengil, Erhan; Ozer, Cahit; Arica, Secil; Ozler, SerkanAim: Urinary incontinence (Ul) is fairly common among women and reduces common emotional and psychological well-being and also a phenomenon that weakens sexual life. At the same time social activities and relationships; family life, his relationship with his Wife is adversely affected. In this study of prevalence of Ul and the sexual dysfunction(SD) and quality of life. were examined in women of reproductive age who admitted family medicine, obstetrics, urology clinics With various symptoms. (frequent urination; urinary burning; pelvic pain, urinary incontinence, vaginal discharge and similar complaints). Materials and methods: The study included a total of 665 female patients of 15-49 years of age admitted to Family Medicine, Obstetrics and Gynecology, and Urology polyclinics in Mustafa Kemal University Faculty of Medicine, Training and Research Hospital during October 2013-January 2014 with various complaints. General survey form ICIQ-SF (International Consultation on Incontinence Short Form), FSFI (Female Sexual Function Index) form; and EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30) version 3.0 were applied to these patients The general survey form addressed demographic characteristics, risk factor for urinary incontinence, concomitant diseases, anamnesis including medical history and family history. The data obtained in the study were assessed for statistical significance by using Student's (t-test, Mann Whitney U test, Chi,square test and Fisher's Exact Chi-square test. Results: The sociodemographic characteristics of the women were; mean age was 31.85 +/- 9.495 (SD) and mean body mass index (BMI) value was 26.39 +/- 4.03. Obstetric history was as follows; number of normal vaginal births was 317 (47,66%);number of caesarean sections 471 (70.8%); number of deliveries of infant over 4 kg of birth weight 138 (20.8%) and number of multiple gestations resulting in live birth was 60(9%) 235(35 3%) women had previous history of surgery to pelvic floor and 203 (30,5%). of had previous history of abdominal surgery (except cesarean section). Frequency of Ul was 42,7%(284 women) Situation that provokes Ul; mixed type at 95 (143%) women, stress type at 133 (20%) women, urge type at 56 (8.4%) women. The effect on daily life was scored(those who report an effect of 8 on a scale to 10 was 159 (23.9%) of). There was chronic disease at 175(26,4%) of them, disc herniation at 36 (5.4%) of, involuntary defecation at74 (11.1%)of, involuntary flatulence at 191 (28.7%) of, haemorrhoids at 405 (60.9%)of urinary tract infection at 244 (36,7%), vaginitis 1-2 times a year at 352 (52.9%) women. Sexual dysfunction (FSFI according to survey results); 215 (32.3%) Women have-not heard of sexual desire in the past month. Self-confidence about being sexually driven present at only in 222 (33.4%) women. 307 (46.2%) women dont feel wetness during sexual intercourse. 136(20.5%) women say sexual intercourse is not satisfactory. 57.9% of all cases not satisfied with your sexual life. Painful intercourse at 74 (11.1%) women. Conclusion: Urinary incontinence in female population is quite a common health problem. A large majority of women perceive it as a result of aging and female gender and do not seek medical assistance it is important to detect this problem and relevant risk factor among patients who admit to palyclinics. This approach would improve the treatnient of this condition which affects quality of life and sexuality.Öğe Relationship between endothelial dysfunction and nocturia with benign prostatic hyperplasia(Taylor & Francis Ltd, 2013) Inci, Mehmet; Sarli, Bahadir; Davarci, Mursel; Yalcinkaya, Fatih Rustu; Rifaioglu, Murat Mehmet; Davran, Ramazan; Arica, SecilObjective. There are limited data on whether there is an association between nocturia, benign prostatic hyperplasia (BPH) and endothelial dysfunction. The aim of the present study was to evaluate whether there is an association between nocturia and endothelial dysfunction in patients with BPH. Material and methods. Forty-two men with a diagnosis of BPH and 42 age-matched controls were enrolled. All patients were assessed for frequency and duration of nocturia, and prostate volume, completed the International Prostate Symptom Score (IPSS) questionnaire, and underwent brachial flow-mediated dilatation (FMD) evaluation. Results. There was a negative correlation between FMD and frequency of nocturia (r = -0.879, p < 0.0001). Moreover, there was a negative correlation between duration of nocturia and FMD (r = -0.890, p < 0.0001). In addition, FMD was significantly decreased in the BPH group compared with the control group (6.0 +/- 0.09 to 7.8 +/- 0.10%) (p = 0.0001). Conclusion. In patients with BPH, nocturia is associated with endothelial dysfunction and may be an insidious risk factor for cardiovascular disease.Öğe Relationship between mean platelet volume and retinopathy in patients with type 2 diabetes mellitus(Springer, 2014) Tuzcu, Esra Ayhan; Arica, Secil; Ilhan, Nilufer; Daglioglu, Mutlu; Coskun, Mesut; Ilhan, Ozgur; Ustun, IhsanObjectives To evaluate the effect of mean platelet volume (MPV) on diabetic retinopathy in patients with type 2 diabetes mellitus. In this study, ocular findings and MPV values were retrospectively reviewed in 192 patients with type 2 diabetes mellitus. The patients were classified into four groups according to ocular findings, as follows: group 1, diabetic patients without diabetic retinopathy (n = 70); group 2, diabetic patients with non-proliferative diabetic retinopathy (n = 64); group 3, diabetic patients with proliferative diabetic retinopathy (n = 58); and group 4, healthy controls (n = 100). A significant difference was found in MPV values between groups 2 and 4 (P = 0.001), between groups 3 and 4 (P = 0.001), and between groups 1 and 4 (P = 0.004). No significant difference was found in MPV values between groups 1 and 2 (P = 0.241) and between groups 2 and 3 (P = 0.460); whereas there was a statistically significant difference between groups 1 and 3 (P = 0.015). The three diabetic groups (groups 1, 2, and 3) were compared with each other. While there was a statistically significant difference between groups 1 and 3 (P = 0.015), there was no significance between groups 2 and 3 (P = 0.46), and between group 1 and 2 (P = 0.241). Logistic regression analysis found a 1.40-fold increase in the risk of retinopathy development (OR: 1.404; P = 0.002) and a 1.46-fold increase in the risk of proliferative diabetic retinopathy (OR: 1.466; P = 0.002) as the MPV value increased. In diabetic patients, the risk of retinopathy development increases with higher MPV values.Öğe Serum adiponectin and resistin levels in patients with obsessive compulsive disorder(Elsevier, 2012) Ari, Mustafa; Ozturk, Oktay Hasan; Bez, Yasin; Arica, Secil; Can, Yesim; Erduran, DuduWe aimed to investigate the changes in serum adiponectin and resistin levels in patients with obsessive compulsive disorder and control groups. The serum adiponectin and resistin levels of 29 patients (16 females, 13 males) with obsessive compulsive disorder and weight, age and sex-matched 31 healthy controls (17 females, 14 males) were determined. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was applied to all groups. ELISA method was used to measure adiponectin and resistin levels. The mean adiponectin level was 11.92 +/- 2.04 ng/ml and resistin level was 13.23 +/- 2.78 ng/ml in obsessive compulsive disorder group, while it was 18.81 +/- 5.24 ng/ml and 8.17 +/- 2.53 ng/ml in control group. Changes in plasma adiponectin and resistin levels in obsessive compulsive disorder may have implications about possible cardiovascular and metabolic abnormalities seen in obsessive compulsive patients. (C) 2011 Published by Elsevier B.V.Öğe Serum zinc levels in children of 0-24 months diagnosed with pneumonia admitted to our clinic(E-Century Publishing Corp, 2011) Arica, Secil; Arica, Vefik; Dag, Huseyin; Kaya, Aysen; Hatipoglu, Sami; Fenercioglu, Aysen; Karatekin, GunerAim: We have planned to study the relationship between zinc (Zn) plasma levels, as well as pneumonia criteria, and zinc in healthy children younger than 2 years of age compared to pediatric patients diagnosed with pneumonia and admitted to a hospital. Materials and methods: The study enrolled 25 patients of 0-24 months referring to our hospital's pediatric clinic, who were then diagnosed with bronchopneumonia based on the World Health Organization diagnostic criteria and admitted to suckling children clinic due to inability to receive out-patient treatment, and 10 healthy children of the same age group, whose physical examinations revealed no pathological findings. Results: There was no difference between the groups in terms of age and gender distribution (p > 0.05). The control group included in the study showed a significantly higher mean duration of breast milk intake compared to the patient groups (p<0.001). WBC values obtained from the patient group was significantly higher than that of the control group (p<0.001). Zn and iron (Fe) values as determined in the control group enrolled in the study were significantly higher compared to the patient group (p<0.01). Mean total protein in the control group was found to be significantly higher versus that of the patient groups (p<0.05). With regard to the r values of correlation coefficients of the subjects enrolled in the study, a slightly positive correlation was observed between Zn levels and iron levels (r=0.457). Conclusion: It was concluded that infections, particularly pneumonia, which present a serious issue both in our country and developing countries, may be developed more commonly among children with zinc deficiency.
