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Öğe The evaluation of the Denver developmental screening test on moderate and severe level premature infants at pre-school age (Between 4-6 years)(Nobelmedicus, 2016) Baş, Evrim Kıray; Bülbül, Ali; Arslan, Selda; Elitok, Pınar Gizem; Uslu, Sinan; Baş, Vedat; Zubarioğlu, UmutObjective: By conducting this study, our aim is to early diagnose the developmental problems of premature infants that may have been oversighted during the routine medical examination by using the Denver Developmental Screening Test (DDST). Material and Method: The medical profiles of the infants who were admitted to the clinic between the dates of January 2005 and December 2007 with gestational age of <34 weeks were examined retrospectively. These cases of pre-school infants (aged 4-6) were called for a control and tested DDST. Results: Fifty six infants with gestational age of <34 weeks who were admitted to the clinic between January 2005 and December 2007 were examined. The mean gestational age was found to be 30.1±2.4 weeks and the birth weight was found as 1342±331.5 g respectively. Within the 56 premature cases who were tested DDST at the average age of 5.1±1.4 (4.1-6.4) 6 cases (10.7%) demonstrated developmental delay. Birth weight under 1500 g, gestational age of <32 weeks and existence of meningitis were diagnosed to be risk factors in the cases of premature infants. Conclusion: The fact that the presence of developmental delay is only in the 10.7% of the cases we have conducted the DDST can be interpreted as a promising result, meaning the high-quality neonatal care may give the prematurely born infants a chance to survive without any handicap. © 2016, Nobelmedicus. All rights reserved.Öğe Protective Effect of Ellagic Acid on Paraquat-induced Kidney Hazards in Rats(Iranian Soc Nephrolgy, 2017) Silfeler, Ibrahim; Alp, Harun; Dorum, Bayram Ali; Nacar, Emel; Arslan, Selda; Uygur, VeliIntroduction. Paraquat is a commonly used highly toxic herbicide. Despite many studies on detoxification of paraquat, an efficient and safe antidote has not been introduced for toxic cases in human being. The aim of this study was to investigate the effect of ellagic acid (EA) on paraquat-induced kidney hazards in rats. Materials and Methods. Sixty rats were randomly assigned as controls and 5 treatment groups (n = 10 each) receiving EA only, paraquat at doses of 15 mg/kg and 45 mg/kg, and paraquat at the same doses plus EA. Paraquat was intraperitoneally injected and the EA was orally given. Kidney tissues were stained with hematoxylin-eosin for histopathologic investigation. Results. Pathologic scoring showed that paraquat at the higher dose was associated with higher scores than the in the controls, EA group, and the high-dose paraquat group with EA treatment (P < .001 for all comparisons). It was noted that paraquat caused a serious damage in the kidney and the EA treatment significantly reduced the extent of the damage. Conclusions. This study showed the protective effects of EA against paraquat-induced nephrotoxicity histologically. Ellagic acid provided significant improvement in glomerular and tubular structure.Öğe Sirenomelia/mermaid syndrome without imperforate anus in a premature infant(Elsevier Science Bv, 2018) Atici, Ahmet; Celikkaya, Mehmet Emin; Arslan, Selda; El, Cigdem; Akcora, Bulent[Abstract Not Available]
