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Öğe Assessment of the levels of nitric oxide (NO) in chronic diarrhea patients infected with Giardia intestinalis(Academic Journals, 2012) Kaya, Ozlem M. Aycan; Atambay, Metin; Yula, Erkan; Ozyalin, Fatma; Motor, Vicdan Koksaldi; Motor, Sedat; Celik, MuratGiardia intestinalis is an enteric pathogen causing certain digestive disorders by attaching itself on the human intestine and, especially on the duodenum. It is reported that there is a strong relationship between the nitric oxide (NO) level and the clinical prognosis of the infection in infections of G. intestinalis. The aim of the study was to investigate serum NO levels in samples taken from patients with G. intestinalis detected in the microscopic stool examination and from the control group consisting of healthy people and the presence of any relationship with Giardiosis. The study consisted of 60 patients diagnosed with G. intestinalis in microscopic stool examination, [31 (51.7%) male, 29 (48.3%) female] and 60 healthy people [28 (46.7% male, 32 (53.5%) female] as the control group. All patients in the patient group with gastrointestinal symptoms had chronic diarrhea and cysts and trophozoites were observed in microscopic examination of the feces in all of them. Measurement of serum NO level was performed using Cortas method. When the data were evaluated by T-test in the Independent Groups, NO levels in the patient group was found low at a statistically significant level. In Giardiosis, the decline in the NO level suggested that the disease causes a more severe clinical presentation. In addition to this, we consider it necessary that extensive experimental or clinical studies be conducted on the subject.Öğe Prevalence of Demodex folliculorum and Demodex brevis in the Eyelash Follicles of Healthy Subjects(Kafkas Univ, Veteriner Fakultesi Dergisi, 2012) Aycan-Kaya, Ozlem; Atambay, Metin; Daldal, NilgunDemodex folliculorum and Demodex brevis mites are parasites of humans only. These mites are usually found on face, eyebrows, eyelashes and meibomian glands. When they appear in large numbers in eyelashe follicules, they may cause Demodex blepharitis. The aim of this study was to determine the prevalence of Demodex species on eyelashes of healthy individuals. Eyelashes were collected from 131 healty individuals who did not have a history of blepharitis. While D. folliculorum was detected in 17 (13.0%) people, D. brevis was only seen in four individuals (3.1%), the differences being statistically significant. It was observed that D. folliculorum occurs more commonly in older people and male/female rates were not different. Since the D. brevis was rarely found in eyelashes, cases of blepharitis are believed to be the result of the co-existance of D. brevis and D. folliculorum.Öğe Sağlıklı kişilerin kirpiklerinde demodex folliculorum ve demodex brevis görülme sıklığı(2012) Aycan Kaya, Özlem; Atambay, Metin; Daldal, NilgünDemodex folliculorum ve Demodex brevis sadece insanlarda parazitlenen akarlardır. Genellikle hastaların yüzünde yaygın olup, kaşlarda, kirpiklerde, meibomian bezlerde, hatta vücudun diğer bölgelerinde rastlanabilmektedir. Fazla sayıda Demodex ile oluşan göz tutulumu sonrası blefarit görülebilmektedir. Çalışmada sağlıklı kişilerin kirpiklerinde Demodex türlerinin yaygınlığının belirlenmesi amaçlanmıştır. Herhangi bir kirpik enfeksiyonu geçirmemiş ve şikayeti olmayan 131 kişiden kirpik epilasyonu ile örnek alınmıştır. 17 (%12.97) kişide D. folliculorum saptanırken 4 (%3.05) kişide D. brevis görülmüştür. Fark istatistiksel olarak anlamlı bulunmuştur. Parazit varlığının cinsiyete göre değişmediği gözlenmiştir. Sağlıklı kişlerin kirpiklerinde D. brevis'e az rastlanması nedeniyle blefarit olgularına D. brevis'in D. folliculorum ile birlikte bulunmasının neden olabileceği düşünülmüştürÖğe Sociodemographic characteristics of patients with Demodex brevis and Demodex folliculorum infestation and its association with rosacea and Behcet's disease.(Allied Acad, 2015) Durmaz, Suleyman; Yula, Erkan; Kaya, Ozlem Aycan; Gokmen, Aysegul Aksoy; Kilinc, Cetin; Atambay, Metin; Ekiz, OzlemDemodex mites are ectoparasites often found in the skin thought to be associated with the development of some skin diseases. Demodex positivity may be affected by several factors. In order to determine the relationship between Demodex infestation and rosacea disease (RD), Behcet's disease (BD) and various individual parameters such as gender, personal hygiene and skin type. A total of 238 individuals (61 with RD, 46 with BD, and 131 healthy subjects) were investigated for the presence of Demodex folliculorum and D. brevis using the standardized skin surface biopsy technique and a questionnaire. The incidence of Demodex mites in RD patients was significantly higher when compared to the control group (p=0.010 and p=0.001, respectively). However, there was no difference between those with BD and the control group. There was a significant difference between ages of groups, skin types, use of moisturizer, and itching, without taking into account the presence of Demodex among the disease groups (p<0.05). On the other hand, there was no significant difference between disease groups in terms of data of gender, skin care, epilation, and face washing. Our study reveals that the positivity rates of Demodex mites in rosacea patients were significantly higher. Mean ages of groups, skin types, use of moisturizer, and the presence of itching of the ear and face may be associated with higher density of Demodex mites.Öğe Sociodemographic characteristics of patients with demodex brevis and demodex folliculorum infestation and its association with rosacea and behçet’s disease(Scientific Publishers of India, 2015) Durmaz, Suleyman; Yula, Erkan; Aycan Kaya, Ozlem; Aksoy Gokmen, Aysegul; Kilinc, Cetin; Atambay, Metin; Ekiz, OzlemDemodex mites are ectoparasites often found in the skin thought to be associated with the development of some skin diseases. Demodex positivity may be affected by several factors. In order to determine the relationship between Demodex infestation and rosacea disease (RD), Behçet’s disease (BD) and various individual parameters such as gender, personal hygiene and skin type. A total of 238 individuals (61 with RD, 46 with BD, and 131 healthy subjects) were investigated for the presence of Demodex folliculorum and D. brevis using the standardized skin surface biopsy technique and a questionnaire. The incidence of Demodex mites in RD patients was significantly higher when compared to the control group (p=0.010 and p=0.001, respectively). However, there was no difference between those with BD and the control group. There was a significant difference between ages of groups, skin types, use of moisturizer, and itching, without taking into account the presence of Demodex among the disease groups (p<0.05). On the other hand, there was no significant difference between disease groups in terms of data of gender, skin care, epilation, and face washing. Our study reveals that the positivity rates of Demodex mites in rosacea patients were significantly higher. Mean ages of groups, skin types, use of moisturizer, and the presence of itching of the ear and face may be associated with higher density of Demodex mites. © 2015, Scientific Publishers of India. All rights reserved.Öğe What is the Importance of Demodex folliculorum and D. brevis in the etiology of blepharitis?(Turkiye Klinikleri, 2013) Yula, Erkan; Aycan Kaya, Özlem M.; Atambay, Metin; Do?anay, Selim; Daldal, Nilgün; Ayhan Tuzcu, EsraObjective: It was reported that, Demodex folliculorum (DF) and D. brevis (DB) may cause an infestation in healthy subjects and, may be important for some eye problems such as blepharitis, or these parasites can bring the present disease into a more serious condition. In this study, we aimed to determine which demodex species' density increase in patients with blepharitis and whether the demodex density on face differs from healthy subjects. Material and Methods: In the study, the presence of demodex species was analyzed on eyelashes and faces of 96 patients with blepharitis and 197 healthy subjects. Samples taken through standard superficial skin biopsy technique and eyelash epilation were analyzed with the light microscope. Results: The mean age of the patients with blepharitis was 46.90±16.92 (15-89) years, whereas the mean age of control group was 39.54±17.61 (12-84) years. Among eyelash samples of the patients, 78 (81.25%) samples were found DF positive, whereas 25 (26.04%) of them were found DB positive; on the contrary 30 (15.22%) and 7 (3.55%) of the control group was DF and DB positive, respectively. Among the eyelash samples of the patients, the demodex incidence was statistically significantly higher compared to the control group (p<0.001). There was no significant difference in terms of demodex positivities on face. All patients who were demodex positive on the facial area were also found demodex positive for eyelash samples whereas 8 (24.2%) of eyelash samples were Demodex spp positive in the control group (p<0.001). Conclusion: The results of our study underline that the presence of Demodex spp on facial area may be one the important factors in the pathogenesis of blepharitis. In conclusion, we suggest that taking the demodicosis presence into consideration as a worsening factor may help in the management of blepharitis. © 2013 by Türkiye Klinikleri.
