Yazar "Atilgan, H., I" seçeneğine göre listele

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    Öğe
    The Cytokines-Directed Roles of Spirulina for Radioprotection of Lacrimal Gland
    (Taylor & Francis Inc, 2023) Atilgan, H., I; Akbulut, A.; Yazihan, N.; Yumusak, N.; Singar, E.; Koca, G.; Korkmaz, M.
    Purpose To evaluate the radioprotective effect of spirulina (SP) on the lacrimal glands after RAI treatment. Methods A total of 30 rats were separated into control, RAI and SP group. The radioprotective effect of SP on lacrimal glands was evaluated with histopathological and cytopathological analysis. Lacrimal glands were analyzed for tumor necrosis factor alpha (TNF-alpha), interleukin-2 (IL-2), IL-4, IL-6, IL-10, nuclear factor-kappa B (NF-kappa B), total oxidant status (TOS) and total antioxidant capacity (TAC) levels. Results RAI increased TNF-alpha (p = .001), IL-6 (p = .018), and NF-kappa B levels (p < .0005). Following the administration of SP, TNF-alpha (p < .0005), IL-4 (p = .026), and IL-6 (p = .006) levels decreased. RAI decreased the TAC levels (p = .001), and co-administration of SP increased the TAC level, but was not statistically significant. SP decreased the TOS level after RAI (p = .022) . Conclusions SP protects lacrimal glands from RAI-induced damage.
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    Öğe
    AN EVALUATION OF THE OCCUPATIONAL EXTERNAL RADIATION EXPOSURE OF PERSONNEL IN NUCLEAR MEDICINE PRACTICES (2010-2020)
    (Oxford Univ Press, 2022) Sahmaran, T.; Atilgan, H., I; Nur, S.; Sahutoglu, G.; Yalcin, H.
    The aim of this study was to examine the radiation doses received by personnel working in the Nuclear Medicine Department between 2010 and 2020. The data obtained were compared with the dosages recommended by international authorities. The UNSCEAR 2008 report stated that the worldwide annual average effective dose to which personnel were exposed when monitored between 2000 and 2002 was 0.70 and 1.40 mSv, respectively. In this report, 0.7 mSv refers to the dose of all monitored personnel, and 1.4 mSv refers to the dose above the detection limit. In this study, the annual average effective dose value for personnel exposed to radiation was calculated as 1.65 mSv. This value represents the dose above the detection limit. Although the individual dose results are below the recommended annual dose limit, it should not be forgotten that more effort should be made to reduce radiation doses using the as low as reasonable achievable principles.