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    Evaluation of the efficacy of several sclerosing agents for pleurodesis in rats
    (Marmara Univ, Fac Medicine, 2022) Balta, Cenk; Kuzucuoglu, Mustafa; Aslan, Figen; Yekdes, Ali Cem
    Objective: This study aims to evaluate the efficiencies and effects of different sclerosing agents. Materials and Methods: Thirty-five female Wistar-albino rats were included in this study and divided into five groups randomly. Isotonic saline (group 1), iodopovidone (group 2), rifamycin (group 3), autologous blood (group 4), talc (group 5) were given into intrapleural space. On postoperative 28th day, ipsilateral and contralateral pleural and parenchymal fibrosis and inflammation were evaluated. Results: There were statistically differences between control and other groups on macroscopically pleural fibrosis examination (p=0.004, p=0.001, p=0.001, p=0.000, respectively). Microscopically pleural fibrosis were determined in all groups when compared to control group (p=0.023, p=0.023, p=0.035, p=0.001, respectively). There were no significant differences between sclerosing agent groups (p>0.05). Significant differences were observed according to microscopic pleural inflammation evaluation between talc group and other groups. There was superiority in talc group according to intraparenchymal inflammation grade compared to other groups (p=0.010, p=0.042, p=0.030, respectively). Macroscopically, fibrosis and microscopically, inflammation were significantly observed between talc and other groups in the contralateral pleura (p=0.037and p=0.009, respectively). Conclusion: lodopovidonc, autologous blood, talc, and rifamycin can be used as effective pleurodesis agents. However, we found that rifamycin and autologous blood are safer as effective pleurodesis agents. We think that these two agents can be used in patients with secondary lung diseases due to their less intraparenchymal inflammation rates. It may be advantageous to prefer other sclerosing agents which has lower costs and less side effects comparing to talc.
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    EVALUATION OF TOTAL INTRAVENOUS PORT CATHETER PROCEDURES WITH ULTRASONOGRAPHY
    (2022) Kuzucuoğlu, Mustafa; Albayrak, İlkay; Balta, Cenk
    Aim: In our study, we aimed to evaluate our total intravenous port catheter procedures accompanied by ultrasonography.\rMethods: 107 patients over 18 years of age who underwent total intravenous port catheter with ultrasonography in order to perform oncological treatment between January 2014 and January 2019 were included in the study. The files of the patients included in the study were analyzed retrospectively and patient demographic information, malignancy type, accessed vein, duration of operation, and complication rates were evaluated. Patients under 18 years old and whose records could not be reached were excluded from the study.\rResults: 72 of the patients included in the study were male and 35 were female, and their mean age was 61.38 ± 11.26. While catheter was placed in the internal jugular vein in 105 of the patients who applied total intravenous port catheter, 2 of patients were placed in the subclavian vein. During the procedure, complications developed in 16 (14.95%) patients. These were arterial puncture and hematoma in 11 patients, pneumothorax in 3 patients, hemothorax in 1 patient, and hemopneumothorax in 1 patient.\rConclusion: The use of ultrasonography in total intravenous port catheter lengthens the processing time and decreases the complication rate as the experience of use increases.