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    Aortic Arterial Stiffness is a Moderate Predictor of Cardiovascular Disease in Patients With Psoriasis Vulgaris
    (Sage Publications Inc, 2014) Balta, Ilknur; Balta, Sevket; Demirkol, Sait; Celik, Turgay; Ekiz, Ozlem; Cakar, Mustafa; Sarlak, Hakan
    Psoriasis is associated with an increased risk of atherosclerosis. Endothelial dysfunction is the critical early step in the process of atherogenesis, and it is commonly investigated by measuring arterial stiffness. We aimed to investigate the relationship between arterial stiffness and high-sensitivity C-reactive protein (hsCRP) in patients with psoriasis. A total of 32 patients with psoriasis and 35 patients with other skin diseases were included in the study. The hsCRP levels and arterial stiffness measurements were compared. Arterial stiffness was significantly different between the 2 groups (P = .01). Arterial stiffness was not associated with the duration of the disease or the disease activity (P = .34 and .64, respectively). In patients with psoriasis, arterial stiffness correlated positively with age, sex, body mass index, diastolic blood pressure, and hsCRP level (P < .05). These findings provide further evidence of a link between inflammation, premature atherosclerosis, and psoriasis.
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    Arterial Stiffness Parameters Should be Evaluated With Different Types of Psoriasis
    (Sage Publications Inc, 2014) Balta, Ilknur; Balta, Sevket; Demir, Mustafa; Demirkol, Sait; Ekiz, Ozlem; Unlu, Murat
    [Abstract Not Available]
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    The Association Between Inflammatory Markers and the Degree of Psoriasis Vulgaris
    (Sage Publications Inc, 2014) Balta, Ilknur; Balta, Sevket; Demirkol, Sait; Ekiz, Ozlem; Sarlak, Hakan; Cakar, Mustafa
    [Abstract Not Available]
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    The Etiology of Behcet Disease: Is It Really Inflammation or Not!
    (Sage Publications Inc, 2014) Ekiz, Ozlem; Balta, Ilknur; Sen, Bilge Bulbul; Rifaioglu, Emine Nur; Balta, Sevket; Demirkol, Sait
    [Abstract Not Available]
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    Mean Platelet Volume as an Inflammatory Indicator in Behcet Disease
    (Sage Publications Inc, 2014) Ekiz, Ozlem; Balta, Ilknur; Sen, Bilge Bulbul; Rifaioglu, Emine Nur; Balta, Sevket; Demirkol, Sait
    [Abstract Not Available]
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    Mean Platelet Volume in Recurrent Aphthous Stomatitis and Behcet Disease
    (Sage Publications Inc, 2014) Ekiz, Ozlem; Balta, Ilknur; Sen, Bilge Bulbul; Rifaioglu, Emine Nur; Ergin, Can; Balta, Sevket; Demirkol, Sait
    Behcet disease (BD) and recurrent aphthous stomatitis (RAS) are systemic inflammatory diseases, but the exact pathogenesis of both the diseases is unknown. Mean platelet volume (MPV) is an indicator of platelet activation. The aim of this study was to investigate the MPV levels in patients with BD, RAS, and healthy participants. A total of 61 patients with BD, 60 patients with RAS, and 60 healthy controls were included in this study. The MPV levels and erythrocyte sedimentation rate in patients with BD and RAS groups were significantly higher than the control groups (P < .001). In the BD group as well as in the RAS group, the disease activity does not affect the levels of MPV. The MPV levels may be used as a cheap and feasible diagnostic marker in patients with BD and RAS. Nevertheless, the MPV does not have a predictive value in differentiating the diagnosis of BD and RAS.
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    Nutritional anemia in reproductive age women with postadolescent acne
    (Taylor & Francis Ltd, 2013) Balta, Ilknur; Ekiz, Ozlem; Ozuguz, Pinar; Sen, Bilge Bulbul; Balta, Sevket; Cakar, Mustafa; Demirkol, Sait
    Context: Postadolescent acne has been defined as the presence of acne beyond the age of 25 years. Postadolescent acne affects approximately 14% of women between the ages of 25 and 50 years. Namely, postadolescent acne usually occurs in women of reproductive age. Nutritional anemia occurs from an insufficient intake of nutrients such as iron, folate and vitamin B12. It is very common in women of reproductive age. Nutritional anemia causes irritability, apathy, fatigue, depressive symptoms and difficulty in concentration. The major etiological factor in adult acne can be increased levels of emotional stress, leading to increase in adrenal androgens. Thus, nutritional anemia may aggravate the lesions of acne by affecting the emotional status in women of reproductive age. Objective: We aimed to investigate the relationship between postadolescent acne and nutritional anemia in this study. Materials and methods: The study population comprised of 52 patients with postadolescent acne and 52 healthy control subjects. Hemogram, vitamin B12, folate, serum iron, ferritin and total iron-binding capacity (TIBC) were measured. Results: No significant differences were observed between both groups in hemoglobin, vitamin B12, serum iron, ferritin and TIBC levels. Serum folate levels were significantly decreased in postadolescent acne patients (p<0.001). There were no significant correlations between hemoglobin, vitamin B12, folate, serum iron, ferritin and TIBC levels and acne severity. Discussion and conclusion: We could not find any relationship between postadolescent acne and nutritional anemia in our study. However, serum folate levels were decreased in postadolescent acne patients. Prospective research studies are needed to clarify the role of nutrition in the pathophysiology of postadolescent acne. We think that nutritional interventions can be inexpensive, safe, easy to administer and generally acceptable to patients with postadolescent acne.