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    Association of Helicobacter pylori positivity with the symptoms in patients with hyperemesis gravidarum
    (Springer Heidelberg, 2013) Gungoren, Arif; Bayramoglu, Neslihan; Duran, Nizami; Kurul, Mehmet
    To investigate the relationship between Helicobacter pylori (Hp) positivity and the severity of symptoms of nausea and vomiting in patients diagnosed with hyperemesis gravidarum (HG). Prospective controlled. Ninety patients with the diagnosis of HG below the 20th week gestation, who had no additional disease and 50 pregnant women with no complaints were enrolled in the study. According to the severity of symptoms, the patients were divided into three groups as group I, II and III (mild, moderate and severe, respectively). The Rhode's scoring system was used to determine the severity of HG symptoms. HpIgG and IgM levels were determined in the blood samples and Hp DNA positivity with PCR was investigated in the saliva. In accordance with the Rhode's scoring system, 15.5 % of the pregnant women had mild, 58.9 % had moderate, and 25.6 % had severe symptoms (group I, II and III, respectively). HpIgG was determined as positive in 78.6, 84.9 and 82.6 % in groups I, II and III, respectively. HpIgM positivity was determined as 26.1 % only in group III (p = 0.847). HpDNA was determined as 7.2, 3.8, and 91.3 % in group I, II, and III, respectively (p < 0.01). While HpIgG was positive in 60 %, HpDNA was found to be positive in 2 % and HpIgM was found to be negative in all the pregnant women in the control group. A positive relationship between the symptoms of HG and Hp positivity was determined using PCR.
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    Investigation of the presence of Trichomonas vaginalis in infertile Turkish women
    (Walter De Gruyter Gmbh, 2015) Kaya, Ozlem Aycan; Silfeler, Dilek Benk; Kurt, Raziye Keskin; Gozukara, Ilay; Yengil, Erhan; Bayramoglu, Neslihan
    Background: Trichomoniasis is a sexually transmitted vaginal infection caused by a protozoan called Trichomonas vaginalis. Its prevalence ranges between 3-40% among randomly tested women. Objectives: To investigate the presence of T vaginalis in infertile women presenting to a Turkish gynecology outpatient clinic using parasitological methods. Methods: The study population comprised 51 patient participants who attended the gynecology clinic of Mustafa Kemal University Hospital between March and August 2013. The women were divided into those presenting with infertility (n = 22) and a patient control group (n = 29). Women in the control group had complaints other than infertility. Microscopic examination, Giemsa staining, and cysteine peptone liver maltose culture were performed on samples taken from posterior fornix tested for T vaginalis. Results: T vaginalis was observed in 18% (n = 4) of infertile patients and in none of the control group (P = 0.03). Conclusions: Asymptomatic infertile women should be examined for T vaginalis infection, which may play a role as a cause or contributing factor in infertility.