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    Quantitative Brain Diffusion-Tensor MRI Findings in Patients With Sickle Cell Disease
    (Amer Roentgen Ray Soc, 2012) Balcı, Ali; Karazincir, Sinem; Beyoglu, Yeliz; Cingiz, Cihangir; Davran, Ramazan; Gali, Edip; Okuyucu, Esra
    OBJECTIVE. The aim of this study was to evaluate the microstructure of various regions of the brain using diffusion-tensor imaging (DTI) in patients with sickle cell disease (SCD) and in age- and sex-matched healthy control subjects. We also investigated the fiber tractography findings of the corpus callosum (CC) and corticospinal tracts (CSTs). SUBJECTS AND METHODS. Sixteen right-handed patients with SCD and 14 age- and sex-matched right-handed healthy control subjects were scanned using conventional MR sequences and DTI. Fractional anisotropy (FA) and apparent diffusion coefficients (ADCs) were calculated and regions of interest were selected in various brain areas (superior and inferior frontal, parietal, occipital, and temporal white matter areas), anterior and posterior periventricular areas, centrum semiovale, basal ganglia (lentiform nucleus, head of caudate nucleus), thalamus, cerebral peduncles, pons, cerebellar white matter areas, and CC. Diffusion-tensor tractography of the CC and CSTs was also performed. RESULTS. For the patients with SCD, significantly reduced FA values, increased ADC values, or both were seen clustered in several brain areas, including the CC, frontal white matter, centrum semiovale, periventricular areas, head of the caudate nucleus, thalamus, brainstem, and pons (p < 0.05). Statistically significant reductions in fiber counts in the first and fifth segments of the CC and in CSTs bilaterally were also observed in patients with SCD (p < 0.05). CONCLUSION. DTI shows microstructural abnormalities of various brain areas in patients with SCD.
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    Retrograde filling carotid-cavernous fistula: MSCT angiography findings
    (Springer, 2012) Bayarogullari, Hanifi; Beyoglu, Yeliz; Balci, Ali; Karaoglu, Ece; Davran, Ramazan; Altas, Murat
    [Abstract Not Available]
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    Thyroid Doppler indices in patients with sickle cell disease
    (Elsevier Science Inc, 2013) Karazincir, Sinem; Balcı, Ali; Yonden, Zafer; Gali, Edip; Daplan, Turgay; Beyoglu, Yeliz; Kaya, Hasan
    Objective: To evaluate the intrathyroidal hemodynamic changes and thyroidal volume in sickle cell disease (SCD) patients. Methods: Thirty-two patients with homozygous SCD and 32 control subjects were examined with color Doppler ultrasonography. None of the patients and control subjects had clinical or laboratory evidence of thyroid disease. Results: SCD patients had significantly higher resistance index (RI) and pulsatility index (PI) values and lower thyroid volume compared with control group. Conclusion: Increased intrathyroidal RI and PI and decreased thyroid volume may be due to impaired thyroidal microcirculation. Further and follow-up studies are needed to explain the relationship between Doppler parameters and thyroid functions. (C) 2013 Elsevier Inc. All rights reserved.