Yazar "Can, Yesim" seçeneğine göre listele
Listeleniyor 1 - 8 / 8
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Carcass and Meat Quality Characteristics of White and Multicolor Geese under Local Breeder Conditions(Kafkas Univ, Veteriner Fakultesi Dergisi, 2012) Yakan, Akin; Elmali, Dilek Aksu; Elmali, Mehmet; Sahin, Tarkan; Motor, Sedat; Can, YesimThe purpose of this study was to define the meat quality characteristics of White and Multicolor geese under local breeder conditions. While carcass and edible offal percentages were similar breast, back and wing ratios were statistically different between White and Multicolor geese. Phenotypic color differentiation between geese varieties was reflected on both breast meat and skin (except a* value). While White geese had better values than Multicolor geese for saturated fatty acid and monounsaturated fatty acid, Multicolor geese were higher than White geese for polyunsaturated fatty acid. Nutritive value of White variety was higher than Multicolor variety in breast meat, skin and abdominal fat.Öğe Evaluation of total antioxidant status, total oxidant status and oxidative stress index in patients with alopecia areata(E-Century Publishing Corp, 2014) Motor, Sedat; Ozturk, Sahin; Ozcan, Oguzhan; Gurpinar, Ahmet Burak; Can, Yesim; Yuksel, Rana; Yenin, Julide ZehraObjectives: In this study, we aimed to evaluate total oxidative stress and total antioxidant capacity in serum samples from patients with Alopesia Areata (AA) in our laboratory conditions. Methods: In this study, 46 subjects with AA (26 females, 20 males) and the control subjects of 36 (20 females, 16 males) age-and sex-matched healthy volunteers from our hospital staffs were enrolled (the mean age was 23.7 +/- 11.0 years). Blood samples were obtained following an overnight fasting state, and were collected on ice at 4 degrees C. The serum samples were separated from the cells by centrifugation at 3000 rpm for 15 min and were stored at -80 degrees C and used for the analysis of the Total Antioxidant Status (TAS) and Total Oxidant Status (TOS). Results: Total Antioxidant Status (TAS) and Total Oxidant Status (TOS), Oxidative Stress Index (OSI) (TOS/TAS) levels of AA patients were 1.4777 +/- 0.1986; 9.7490 +/- 6.0445; 0.6593 +/- 0.4069 respectively. TAS; TOS; OSI (TOS/TAS) levels of controls were 1.4028 +/- 0.1687; 9.4627 +/- 4.2781; 0.6875 +/- 0.3232 respectively. TAS, TOS and OSI levels showed no significant difference between the control and AA group (p > 0.05). Conclusion: Future studies about AA pathogenesis should be based not only on oxidant/antioxidant balance but also on several other factors. Because it was observed that the disease showed recurrence in different situations. Since the selection criteria of patients is affected from disease severity and environmental and genetical factors, multicentric studies with better sampled patient population and higher patient number is required.Öğe Increased Plasma Nesfatin-1 Levels in Patients with Obsessive Compulsive Disorder(Kure Iletisim Grubu A S, 2012) Bez, Yasin; Ari, Mustafa; Ozturk, Oktay Hasan; Oktar, Suleyman; Can, YesimIncreased plasma nesfatin-1 levels in patients with obsessive compulsive disorder Objective:To determine and compare the plasma nesfatin-1 (a satiety peptide) levels of patients with obsessive compulsive disorder (OCD) and healthy control subjects. Method: Plasma nesfatin-1 levels of 31 patients with OCD (18 females, 13 males) and 28 healthy control subjects (16 females and 12 males) similar to the study group in terms of weight, age, and gender were measured in this study. Severity of obsessions and compulsions both in OCD patients and control subjects were determined by using Yale-Brown Obsessive Compulsive Scale (Y-BOCS). ELISA method was used to measure plasma nesfatin-1 levels. Results: Median plasma nesfatin-1 levels in patients with OCD and healthy control subjects were 4.61 ng/ml (min-max: 1.28-8.11) and 2.0 ng/ml (min-max: 0.11-4.98) respectively. The observed difference in plasma nesfatin-1 levels between two groups was statistically significant (p<0.001). No statistically significant correlation was observed between Y-BOCS scores and plasma nesfatin-1 levels either in the study group (r=0.205, p=0.27) or in the control group (r=0.335, p=0.071). Conclusion: Increased plasma nesfatin-1 levels observed in patients with OCD suggest a potential role to nesfatin-1 in anxiety states besides its previosly known anorexigenic effects.Öğe Investigation of Vitamin D Levels in Patients with Vitiligo Vulgaris(Croation Dermatovenerological Soc, 2014) Ustunl, Ihsan; Serastan, Gamze; Gokce, Cumali; Motor, Sedat; Can, Yesim; Inan, Mehmet Ugur; Yilmaz, NigarThe aim of the study was to investigate serum 25-hydroxyvitamin D (25(OH) D,) levels in patients with vitiligo vulgaris in terms of causal relation and extension of the disorder. This study is a clinical cross-sectional study carried out in order to determine 25-hydroxyvitamin D levels among 25 patients with vitiligo vulgaris and in 41 controls. Fitzpatrick skin phototypes, history of autoimmune disease, family history of vitiligo, and duration of the disease were also evaluated. The mean levels of vitamin D in patient and the control group were 15.2 +/- 5.2 ng/dL and 14.4 +/- 6.2 ng/dL respectively (P>0.05). In our study, 48% of the patients had insufficient (<30 ng/nnL) and 52% had very low (<15 ng/mL) levels of vitamin D. There was no correlation between age, duration of the disease, and body surface area affected with vitamin D levels. There was no significant difference in vitamin D levels between patients who had family history of vitiligo (5 patients, 20%) and those that did not. Vitamin D levels were found to be insufficient (<30 ng/mL) or very low (<15 ng/mL) in most of the patients with vitiligo vulgar's, but not statistically significantly different as a group when compared to the controls. More studies are needed to differentiate between the effects of low vitamin D levels on pathogenesis of vitiligo vulgaris and lower vitamin D levels as a result of the disease.Öğe Lipoprotein Subfraction Profile and HDL-Associated Enzymes in Sickle Cell Disease Patients(Springer Heidelberg, 2013) Ozturk, Oktay H.; Can, Yesim; Yonden, Zafer; Motor, Sedat; Oktay, Gonul; Kaya, Hasan; Aslan, MutayAlthough hypocholesterolemia is a reported finding in sickle cell disease (SCD), low-density lipoprotein (LDL)/high-density lipoprotein (HDL) subfractions and HDL-associated enzymes have not been determined in SCD patients. Blood was collected from 38 hemoglobin (Hb)A volunteers and 45 homozygous HbSS patients who had not received blood transfusions in the last 3 months. Serum lipids were measured by automated analyzer while LDL and HDL subfraction analysis was done by continuous disc polyacrylamide gel electrophoresis. Serum levels of cholesteryl ester transfer protein (CETP), lecithin-cholesterol acyltransferase (LCAT), apolipoprotein B (apoB) and apolipoprotein A-1 (apoA-I) were determined by enzyme-linked immunosorbent assay (ELISA). Total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels were significantly decreased, while TG levels were significantly increased in SCD patients compared to controls. A significant decrease in intermediate-density lipoprotein (IDL)-C, IDL-B, IDL-A and LDL-1 fractions were seen in SCD patients, while no significant difference was observed in small dense LDL particles. A significant decrease was seen in HDL-large, HDL-intermediate and HDL-small fractions in SCD patients versus controls. Levels of LCAT and ApoA-1 protein measured in SCD patients were significantly lower while no significant difference was observed in CETP and ApoB protein levels compared to controls. The reduction observed in LDL- and HDL-C in SCD patients was reflected as significantly decreased IDL, LDL-1 and HDL-subfractions. Decreased HDL subfractions may possibly lead to the reduced ApoA-1 and LCAT protein levels observed in SCD patients.Öğe Neuroprotective effect of alpha-lipoic acid and methylprednisolone on the spinal cord ischemia/reperfusion injury in rabbits(Taylor & Francis Ltd, 2015) Boyaci, Mehmet Gazi; Eser, Olcay; Kocogullari, Cevdet Ugur; Karavelioglu, Ergun; Tokyol, Cigdem; Can, YesimObjective. The aim of this study is to investigate the putative neuroprotective effect of alpha-lipoic acid (LA) on spinal ischemia/reperfusion (I/R) injury in rabbits. Methods. Thirty-five adult female New Zeland rabbits, weighing 2,000-3,500 g (mean: 2,800), were divided randomly into five groups of seven rabbits each (n: 7) as Group 1: sham, only laparotomy; Group 2 (i/R): I/R; Group 3 (LA): I/R and 100 mg/kg of LA; Group 4 (MP): I/R and 30 mg/kg of methylprednisolone (MP); and Group 5 (LA + MP): I/R and 100 mg/kg of LA plus 30 mg/kg of MP. Results. A statically significant effect of LA, MP, and LA plus MP on lowering malondialdehyde levels both in the blood and in the cerebrospinal fluid (CSF) has been observed. Nitric oxide is significantly decreased in the blood and spinal cord tissues, and also in the CSF but it is not significant. Superoxide dismutase, catalase, and glutathione levels were increased by LA administration. Conclusion. LA exhibits antioxidant efficacy in spinal cord I/R injury, but it cannot decrease the oxidative stress. The histopathological result of the present study also demonstrated that LA has neuroprotective effect in spinal cord injury.Öğe Relationship between Serum Resistin and Lipid Levels in Patients with Psoriasis(Cukurova Univ, Fac Medicine, 2015) Yilmaz, Nigar; Ulutas, Kemal Turker; Dogramaci, A. Cigdem; Inan, M. Ugur; Yuksel, Rana; Can, YesimPurpose: Psoriasis is inflammatory skin disease which has increased risk of cardiovascular disease. The etiology is unknown, yet. In cardiovascular disease, resistin which is secreted from adipose tissue, was found correlated with the levels of total cholesterol and LDL. In our study, we aimed to study the relation of serum resistin and lipid levels in patients with psoriasis and correlation of Psoriasis Area and Severity Index (PASI). Material and Methods: In Mustafa Kemal University, Faculty of Medicine, Department of Dermatology, thirty-seven healthy subjects (group I) and thirty-four patients with psoriasis (group II) were enrolled for two groups. The age, gender, blood pressure, body mass index (BMI) and PASI were determined. The level of resistin and lipid profile were studied in serum. Results: The level of resistin in patients with psoriasis (12,3 +/- 3,0 ng/ml) was found increased compared with healthy subjects (6,4 +/- 2,3 ng/ml) (p=0.001). The level of total cholesterol and LDL were increased in patients with psoriasis compared with healthy subjects, respectively (189 +/- 43 mg/dl; 129 +/- 31 mg/dl) (p<0,05; p=0,01). The level of resistin was determined correlated positively with LDL (r=0,306). The level of resistin was found strong correlated positively with PASI (r=0,669). Conclusion: The high risk of cardiovascular disease in patients with psoriasis is known. In our study, the levels of resistin, total cholesterol, LDL which increase in cardiovascular disease, was found increased in patients with psoriasis and correlated with PASI. The level of resistin may be increased with increasing severity of the disease, so that it is thought to be significant determining like the lipid profile in patients with psoriasis.Öğe Serum adiponectin and resistin levels in patients with obsessive compulsive disorder(Elsevier, 2012) Ari, Mustafa; Ozturk, Oktay Hasan; Bez, Yasin; Arica, Secil; Can, Yesim; Erduran, DuduWe aimed to investigate the changes in serum adiponectin and resistin levels in patients with obsessive compulsive disorder and control groups. The serum adiponectin and resistin levels of 29 patients (16 females, 13 males) with obsessive compulsive disorder and weight, age and sex-matched 31 healthy controls (17 females, 14 males) were determined. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was applied to all groups. ELISA method was used to measure adiponectin and resistin levels. The mean adiponectin level was 11.92 +/- 2.04 ng/ml and resistin level was 13.23 +/- 2.78 ng/ml in obsessive compulsive disorder group, while it was 18.81 +/- 5.24 ng/ml and 8.17 +/- 2.53 ng/ml in control group. Changes in plasma adiponectin and resistin levels in obsessive compulsive disorder may have implications about possible cardiovascular and metabolic abnormalities seen in obsessive compulsive patients. (C) 2011 Published by Elsevier B.V.
