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    Comparison of reaction time and Body Mass Index in football training children and sedentary children
    (Edizioni Minerva Medica, 2015) Dokuyucu, Recep; Demir, T.; Bilgic, M.; Saglik, M.; Punduk, Z.; Daglioglu, O.; Gur, A.
    Aim. Reaction time (RT) is a term that is used to explain the interval time between the appearance of a stimulus and the initiation of the muscular response to that any expected and unexpected stimulus. The RT is varies depending on such factors as type of the stimulus, type of the response, age, gender, education, training status, warming, fatigue condition. In this study, RT and Body Mass Index (BMI) of students playing football and not playing football (sedentary) is investigated. Methods. Total number of 76 eligible children that is playing football for a regularly 6 months (2 days a week) in the football school and total number of 43 sedentary children in Gaziantep is included. Children's weight and height measurements were recorded and body mass index percentiles were calculated. With ten times in a row, not rhythmic sound stimuli were given to children in both groups and average values were recorded. The relationship between RT and age, BMI percentiles were investigated. Average values were compared statistically. Results. RT was significantly short in training children (right foot: P<0.0004 and left foot: P<0.0002). In addition, BMI percentiles in training children is highly significant when compared to sedentary children (P<0.006). Conclusion. Based on these results we demonstrated that a regular fitness training and nutritional status have important contribution to RT. In particular, starting sport at an early age is very important for health.
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    The Effects of Lung Ischaemia/Reperfusion on TRPM Gene Expression
    (Univ West Indies Faculty Medical Sciences, 2021) Atabay, H. D.; Demir, T.; Dokuyucu, Recep; Yumrutas, O.; Oztuzcu, S.; Ceribasi, A. O.; Bayraktar, R.
    Objective: Transient receptor potential melastatin (TRPM) are integral membrane proteins that have broad range of cellular functions. Roles of TRPM2, TRPM3, TRPM4 and TRPM7 among these channels are very important, and their roles in lung ischaemia/reperfusion injury have not been evaluated yet. The aim of this study is to investigate the contribution of these genes in lung ischaemia/reperfusion injury and evaluate histopathology of tissues. Methods: A total of 40 Wistar albino rats were enrolled for the study. Ischaemia was performed by the application of an atramvatic clamp to pulmonary artery. Gene expressions were determined by the semi-quantitative reverse transcription-polymerase chain reaction method. Histopatholical evaluations were held by a standard haematoxyline-eosin staining. Results: The major histopathological tissue damage was observed in ischaemia performed groups, and expression of TRPM channels was found to be obviously downregulated. Substantial changes were determined between TRPM2, TRPM3, TRPM4 and TRPM7 and lung ischaemia/reperfusion injury. In particular; expression of TRPM2 and TRPM7 was reversibly downregulated in ischaemia. Yet, the expression of TRPM3 and TRPM4 was irreversibly downregulated after ischaemia. Conclusion: Consequently, these results indicate that TRPM family of cation channels may have significant roles in the lung ischaemia/reperfusion injury.