Yazar "Dogan, Esin" seçeneğine göre listele

Listeleniyor 1 - 4 / 4
  • Küçük Resim
    Öğe
    Epithelioid Hemangioendothelioma in the Tongue: A Rare Case Report
    (Federation Turkish Pathology Soc, 2023) Cirkin, Deniz S. U. R. M. E. L., I; Secinti, Ilke Evrim; Dogan, Esin; Ozler, Gul S. O. Y. L. U.
    Epithelioid hemangioendothelioma is a rare malignant vascular neoplasm caused by the proliferation of neoplastic endothelial cells. Epithelioid hemangioendothelioma may develop in any organ, but it is commonly observed in the extremities. The tongue is a very unusual location for epithelioid hemangioendothelioma.A 55-year-old male patient presented to the outpatient head and neck clinic with lumps in the tongue, pain, and limitation of motion. The polypoid mass detected in the anterior midline of the tongue was excised. Microscopically, the tumor cells included slightly pleomorphic oval or round vesicular nuclei with an eosinophilic cytoplasm that variably contained vacuoles. There were 4 mitoses per 10 high power fields and there was no necrosis. In immunohistochemical study, the tumor cells were positively stained with CD31 and CD34 whereas they were negatively stained with TFE3, SMA, S-100, HHV-8 and EMA. The patient was diagnosed with epitheloid hemangioendothelioma.Only ten cases have been reported in the tongue in the literature. Our case was the eleventh case, and we aimed to report this case as a rare entity with an unusual location.
  • Küçük Resim
    Öğe
    Histopathologic Evaluation of Parapsoriasis from the Perspective of NB-UVB/PUVA Therapy on the Outcome and Recurrence of the Disease
    (Wolters Kluwer Medknow Publications, 2021) Ozgur, Tumay; Serarslan, Gamze; Dogan, Esin
    [Abstract Not Available]
  • Küçük Resim
    Öğe
    Our clinical experience in pelvic magnetic resonance imaging with vaginal contrast
    (Via Medica, 2023) Keles, Fatma Ozturk; Korkmaz, Inan; Dogan, Esin; Hakverdi, Sibel; Dolapcioglu, Kenan; Karazincir, Sinem
    Objectives: Magnetic resonance imaging (MRI) is an important modality for pelvic imaging. Vaginal distension is provided by the use of vaginal contrast in pelvic MRI, and it plays an important role in staging especially cervical and vaginal cancer. The aim of this study is to show whether the use of vaginal contrast material contributes to the diagnosis in pelvic examination. Material and methods: Between October 1, 2016 and December 30, 2020, a total of 57 patients who underwent pelvic magnetic resonance imaging with vaginal contrast in the radiology clinic were included in the study and evaluated retrospectively. Results: Cervical cancer was detected in 38 of the 57 patients included in the study, and when the vaginal pre-and post-contrast staging of the patients was performed, the pre-contrast stage was found to be high in six patients (15%). Eight of 38 patients diagnosed with cervical cancer underwent surgery. When the pathological and radiological staging of the patients who underwent surgery were compared, they were 100% compatible. Conclusions: The use of vaginal contrast material increases the diagnostic value of MRI in various pelvic pathologies, especially in cervical cancer staging.
  • Küçük Resim
    Öğe
    Should we report Breslow density, a new concept in cutaneous melanoma?
    (Malaysian Journal Pathology, 2021) Secinti, Ilke Evrim; Gursoy, Didar; Erturk, Tugce; Dede, Isa; Ozgur, Tumay; Dogan, Esin
    Introduction: Breslow density is a newly defined biomarker, independent of Breslow thickness. We aimed to investigate the relationship of Breslow density with other clinicopathological prognostic factors and its effect on the overall survival and disease-free survival in patients with cutaneous melanomas. Materials & Methods: This was a single-centre retrospective study of patients (n = 19) diagnosed with cutaneous malignant melanomas in our hospital between 2011 and 2019 were included in the study. The exclusion criteria were in situ melanomas, punch or incisional biopsies and metastasis at the time of the diagnosis. Breslow density was determined by reevaluating slides obtained at the time of the initial diagnoses. The effect of Breslow density on survival was determined using univariate and multivariate Cox proportional risk analyses. Results: In terms of the overall survival, mortality risk increased as Breslow density increased (p = 0.044). Breslow density was not significantly associated with the overall survival in the multivariate model (p = 0.078). In terms of disease-free survival, the risk of metastasis or recurrence increased 1.229-fold in accordance with an increase in Breslow thickness (CI: 1.057-1.428), whereas increased Breslow density increased the metastasis or recurrence risk 1.059-fold (CI: 1.008-1.112). In the multivariate model, only Breslow density was statistically significant (p = 0.046). Conclusions: As a semi-quantitative and subjective measurement, Breslow density is not a completely accurate representation of the invasive tumour load. However, the measurement is practical and low cost and requires no additional equipment. Therefore, Breslow density can be measured in every laboratory. Considering the value of Breslow density in predicting the prognosis in patients with cutaneous melanomas and strong inter-observer compliance observed in the present study, we believe that it would be useful to include this measurement in pathology reports.