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Öğe Effects of lead on lipid peroxidation in rabbits(Indian Veterinary Journal, 2004) Celik, S; Bal, R; Yarsan, E; Durgut, RExperimental evidence suggests that the cellular damage medicated by free radicals can be involved in the pathology associated with lead intoxication. In the erythrocytes of workers exposed occupationally to lead, significant increase in the activities of the antioxident enzymes was reported (Sugawara et al., 1991; Bechara et al., 1993; Skoczynska et al., 1993; Jiun and Hsien, 1994; Skoczynska and Smolik, 1994). The aim of this study was to evaluate the effects of lead at doses of 80 and 160 mg kg(-1) body weight on lipid peroxidation in six-month old New Zealand rabbits.Öğe Evaluation of dogs with colitis and ulcerative colitis using radiographic, electrocardiographic and laboratory findings(Scientific Technical Research Council Turkey, 2003) Durgut, R; Çelik, S; Öztürk, S; Pekkaya, SSixteen dogs with suspected colitis and ulcerative colitis were examined by clinical, radiographic, laboratory and electrocardiographic means from a diagnostic perspective. In the history and clinical examination, mild diarrheic feces mixed with uncoagulated blood and mucus were determined in all dogs. Tenesmus after defecation, mild weight loss and anemia were common observations. Abdominal palpation revealed a palpable thickened large intestine. Biochemical analyses of blood serums showed that potassium levels were increased, and sodium and total protein levels were decreased. A contrast radiographic examination showed that colon walls were thickened; stenosis, dilatation and shortening of the colons had occurred; and the normal shape of the colons had changed. In microbiologic investigations, in eight dogs' feces, Campylobacter spp., Salmonella spp., Clostridium perfringens and Escherichia coli were isolated. In electrocardiograms, there were typically large peaked T waves in all dogs and flattened P waves in only two dogs. P-R and Q-T intervals were prolonged in four dogs and in only one dog widened QRS and bradycardia were present. In conclusion, it is important to evaluate the clinical signs with radiologic, electrocardiographic and laboratory findings when diagnosing colitis and ulcerative colitis in dogs.Öğe Experimental hyperkalaemia in rabbits: Effects of salbutamol and norepinephrine treatments on blood biochemistry and electrocardiography(Akademiai Kiado, 2003) Celik, S; Bal, R; Durgut, RThe effects of salbutamol and norepinephrine on the electrocardiogram (ECG), serum potassium level and enzyme activities were studied in rabbits with hyperkalaemia; norepinephrine and salbutamol may be therapeutically useful. For induction of hyperkalaemia, 300 mM KCl solution was used and then isotonic saline solution containing 6 mug salbutamol and 3.9 mug norepinephrine per ml were administered. Norepinephrine and salbutamol decreased the serum potassium from 7.36 +/- 0.26 and 7.21 +/- 0.31 mmol/L to 5.62 +/- 0.27 and 4.35 +/- 0.33 mmol/L, respectively, and caused the ECG changes (flatness of P wave, widening of QRS complex and bradycardia) to return to the control conditions (time 0). Norepinephrine, but not salbutamol, decreased the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) to the control levels. These results suggest that monitoring of the enzyme activities might be useful as it yields indexes suitable for evaluating the therapeutic approach with norepinephrine in hyperkalaemia.Öğe Kennel cough syndrome of dogs observed in Ankara Province(Indian Veterinary Journal, 2003) Durgut, R; Borku, MK; Ozkok, S; Pekkaya, S; Guzel, M; Ozkanlar, YE[Abstract Not Available]Öğe Subclinical fatty liver syndrome in Damascus goats(Indian Veterinary Journal, 2003) Gonenci, R; Durgut, R; Erdogan, S; Bal, R; Celik, S[Abstract Not Available]
