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    Insulin resistance in patients with post-adolescent acne
    (Wiley-Blackwell, 2015) Balta, Ilknur; Ekiz, Ozlem; Ozuguz, Pinar; Ustun, Ihsan; Karaca, Semsettin; Kacar, Seval Dogruk; Eksioglu, Meral
    BackgroundPost-adolescent acne has been defined as acne in a patient aged >25years. Acne vulgaris first develops at the onset of puberty as a result of hormonal changes. During puberty, there is a transient decline in insulin sensitivity. We hypothesized that insulin resistance might persist after puberty in patients with post-adolescent acne. ObjectivesThis study was conducted in order to investigate the relationship between post-adolescent acne and insulin resistance. MethodsThe study population comprised 35 patients with post-adolescent acne and 35 healthy control subjects. The parameters measured were fasting blood glucose, insulin, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), total cholesterol (TC), triglycerides, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). The homeostasis model assessment of insulin resistance (HOMA-IR) index was calculated for each individual. ResultsNo significant differences were observed between patients with post-adolescent acne and control subjects in fasting blood glucose, fasting insulin, AST, ALT, triglyceride and HDL-C levels, and HOMA-IR index. There were also no correlations between these parameters and the severity of acne. ConclusionsThis study suggests that insulin resistance may not play a major role in the pathogenesis of post-adolescent acne. Hormonal changes, genetic susceptibility, stress, the use of cosmetics, drugs, and environmental factors should be considered in the development of post-adolescent acne.
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    Papular Mycosis Fungoides: A Case Report and Review in the Literature
    (Medknow Publications & Media Pvt Ltd, 2015) Balta, Ilknur; Akbay, Gulfer; Eksioglu, Meral; Astarci, Muzeyyen; Ekiz, Ozlem
    [Abstract Not Available]