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    Galectin-3: A biochemical marker to detect paroxysmal atrial fibrillation?
    (Canadian Soc Clinical Investigation, 2016) Selcoki, Yusuf; Aydin, H. Ibrahim; Celik, Tugrul H.; Isleyen, Ahmet; Erayman, Ali; Demircelik, M. Bora; Demirin, Hilmi
    Purpose: Atrial fibrillation (AF) is the most common form of arrhythmia. AF leads to electrical remodelling and fibrosis of the atria; however, the mechanism(s) remain poorly understood. Galectin-3 is a potential mediator of cardiac fibrosis. The present study aimed to examine the relationship between serum galectin-3 levels and paroxysmal AF. Methods: Forty-six patients with paroxysmal AF and preserved left ventricular systolic function, and 38 age-and gender-matched control subjects, were involved in the study. Serum galectin-3 levels were analyzed with an enzyme-linked immunosorbent assay (ELISA). Results: Serum galectin-3 levels (median 1.38 ng/mL; 1.21 ng/mL-1.87 ng/mL; p < 0.001) were significantly elevated in patients with paroxysmal AF compared with the control. Left atrial diameter was significantly higher in patients with paroxysmal AF (41.2 +/- 3.0 mm vs. 39.6 +/- 3.3 mm). Left atrial diameter was found to be significantly correlated with serum galectin-3 levels in patients with paroxysmal AF (r= 0.378, p = 0.001). Conclusion: Serum galectin-3 levels are significantly elevated and significantly correlated with left atrial diameter in patients with paroxysmal AF.
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    Is Arterial Stiffness a Predictor of Cardiovascular Disease in All Patients With Psoriasis?
    (Sage Publications Inc, 2014) Sen, Bilge Bulbul; Erayman, Ali; Sen, Nihat
    [Abstract Not Available]
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    Is Increased Mean Platelet Volume an Indicator of Subclinical Atherosclerosis in Patients With Behcet Disease?
    (Sage Publications Inc, 2014) Erayman, Ali; Sen, Nihat
    [Abstract Not Available]
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    Is there a relationship between left atrium size and p-wave dispersion in patients with lichen planus?
    (Hospital Clinicas, Univ Sao Paulo, 2013) Sen, Bilge Bulbul; Rifaioglu, Emine Nur; Erayman, Ali; Sen, Nihat
    [Abstract Not Available]
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    Neutrophil-Lymphocyte Ratio and C-Reactive Protein May Be Correlated in Patients With Coronary Artery Ectasia
    (Sage Publications Inc, 2014) Erayman, Ali; Sen, Nihat
    [Abstract Not Available]
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    Relation of red cell distribution width with dipper and non-dipper hypertension
    (Medical Association of Zenica-Doboj Canton, 2016) Buyukkaya, Eyup; Erayman, Ali; Karakas, Esra; Nacar, Alper Bugra; Kurt, Mustafa; Buyukkaya, Sule; Akcay, Adnan Burak
    Aim Red cell distribution width (RDW), an index of erythrocyte size, is associated with high risk for cardiovascular disease. Nondipping hypertension (HT) is lack of nocturnal fall in blood pressure (BP). The association between RDW and non-dipping BP in normotensive and hypertensive patients was investigated. Methods A total of 170 patients were categorized into 4 groups: Normotensive-Dipper (NT-D), Normotensive-Non-dipper (NTND), Hypertensive-Dipper (HT-D) and Hypertensive-Non-dipper (HT-ND). RDW and hs-CRP levels were measured. Results Hypertensive patients had higher RDW and hs-CRP levels (14.5 ± 0.87 vs.12.7 ± 0.66, p<0.001 for RDW; 0.99 ± 0.52 vs.0.63 ± 0.43, p<0.001 for hs-CRP). Besides, the RDW levels were higher in non-dippers (13.0 ± 0.63 vs.12.4 ± 0.55, p<0.001 for NT-ND and NT-D; 14.9 ± 0.78 vs.14.2 ± 0.82, p<0.001 for HT-ND and HT-D) Conclusion RDW is elevated in non-dipping BP both in normotensive and hypertensive subjects, which may be related with increased inflammatory state. © 2016, Medical Association of Zenica-Doboj Canton. All rights reserved.
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    The Relationship between Coronary Collateral Circulation and Neutrophil/Lymphocyte Ratio in Patients with Coronary Chronic Total Occlusion
    (Karger, 2015) Nacar, Alper Bugra; Erayman, Ali; Kurt, Mustafa; Buyukkaya, Eyup; Karakas, Mehmet Fatih; Akcay, Adnan Burak; Buyukkaya, Sule
    Objectives: To investigate the relationship between neutrophil/lymphocyte ratio (NLR) and coronary collateral circulation (CCC) in patients with coronary chronic total occlusion. Subjects and Methods: Our study population consisted of 275 consecutive patients with chronic total occlusion. One hundred and thirty-eight patients with chronic total occlusion were included in the study. They were classified into 2 groups as follows: impaired CCC (group 1: Rentrop grades 0-1) and good CCC (group 2: Rentrop grades 2-3). The NLR was calculated from the complete blood count. Results: The NLR values of the patients with impaired CCC (4.5 +/- 0.7) were significantly higher than of those with good CCC (2.7 +/- 0.6, p < 0.001). In the multivariate logistic regression test, NLR (OR 33.36, 95% CI 8.189-135.7, p < 0.001), high-sensitivity C-reactive protein (hs-CRP; OR 2.152, 95% CI 1.226-3.777, p = 0.008), estimated glomerular filtration rate (OR 1.167, 95% CI 1.049-1.298, p = 0.004) and systolic blood pressure (OR 1.068, 95% CI 1.009-1.1310, p = 0.025) were independent predictors of impaired CCC. The NLR value > 3.55 yielded an area under the curve value of 0.957 (95% CI 0.921-0.992, p < 0.001) and demonstrated a sensitivity of 95% and a specificity of 90% for the prediction of CCC. A moderate correlation between NLR and hs-CRP was observed (r = 0.443; p < 0.001). Conclusion: Our findings reveal that NLR correlates with the impaired development of coronary collaterals. (C) 2014 S. Karger AG, Basel