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    Comparison of osteoconductive properties of three different ?-tricalcium phosphate graft materials: A pilot histomorphometric study in a pig model
    (Churchill Livingstone, 2015) Damlar, Ibrahim; Erdogan, Ozgur; Tatli, Ufuk; Arpag, Osman F.; Gormez, Ulas; Ustun, Yakup
    Aims: The aim of this study was to compare the de novo bone formation ability and osteoconductive effects of three different beta-tricalcium phosphate (beta-TCP) graft materials. The micro-architectural parameters of the newly formed bone tissues were also compared among the different graft materials. Material and methods: Eight male Swiss domestic pigs were used in the study. Five bony defects were made with a trephine bur. Three of the defects were filled with Cerasorb (R), Kasios (R) and Poresorb (R). The fourth defect was filled with an autogenous bone graft. The last defect remained empty. All subjects were sacrificed after 8 weeks. Results: When compared to a negative control group, significant healing was observed in all the groups except the Cerasorb group. The osteoconductivity of the Poresorb group was better than that of the other groups (p < 0.05). The difference in the osteoconductivity of the Kasios and Cerasorb groups was statistically significant (p < 0.05). Comparison of the micro-architectural properties of newly formed bone tissues retrieved from the defects showed that those filled with Poresorb were the best. Conclusion: beta-TCP materials show different results in terms of the volume and characteristics of new bone formation, although they have a similar chemical structure. (C) 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
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    Effects of Smoking on Periimplant Health Status and IL-1?, TNF-?, and PGE2 Levels in Periimplant Crevicular Fluid: A Cross-Sectional Study on Well-Maintained Implant Recall Patients
    (Lippincott Williams & Wilkins, 2013) Tatli, Ufuk; Damlar, Ibrahim; Erdogan, Ozgur; Esen, Emin
    Purpose:The aim of this cross-sectional study was to evaluate the effects of smoking on periimplant health status and inflammatory cytokines interleukin-1, tumor necrosis factor-, and prostaglandin E2 levels in periimplant crevicular fluid (PICF) and to determine their correlation with clinical parameters in well-maintained implant recall patients.Material and Methods:A total of 60 dental implants placed in 60 patients (27 patients were smoker and 33 were nonsmoker) were included in the study. Plaque index, gingival index, probing depth, periimplant bone loss, PICF volume, and biochemical cytokine levels in PICF were determined and analyzed statistically. The correlation between PICF cytokine levels and clinical parameters were also analyzed.Results:All clinical parameters with the exception of plaque scores were significantly higher in the smoker group. Significantly increased levels of cytokines were observed in the smoker group. The correlation between the cytokine levels and clinical parameters were more marked in smokers.Conclusions:Although the implants of the smoker patients seem to be clinically healthy, the results demonstrate that the implants are relatively at risk even if in a well-maintained population.