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Öğe Comparison of selected toxic elements in cow serum and milk samples from industrial and rural regions(Springer-Verlag, 2004) Erdogan, S; Celik, S; Erdogan, Z[Abstract Not Available]Öğe Effect of different dietary levels of Yucca schidigera powder on the performance, blood parameters and egg yolk cholesterol of laying quails(Blackwell Verlag Gmbh, 2003) Kaya, S; Erdogan, Z; Erdogan, SA total of 135 laying quails (Coturnix coturnix japonica ), 9 weeks old, were divided into three dietary treatment groups. Three replicates were assigned to each treatment group consisting of 15 birds per cage. The diet was supplemented with 0, 100 and 200 ppm Yucca schidigera powder and given ad libitum to the quails for a period of 14 weeks. Body weight, egg production, feed consumption and feed efficiency were not different due to dietary treatments among the groups. Increased egg weight was determined in the control group. Yucca powder supplementation decreased serum glucose, cholesterol and triglyceride level in laying quails. Serum total protein concentration was not changed by dietary treatments but albumin level was decreased in quails fed 100 ppm yucca powder. Egg yolk cholesterol concentration was not significantly different among the groups but tended to decline (11.5%) as a result of yucca supplementation. Red Blood Cell (RBC) and White Blood Cell (WBC) counts, packed cell volume (PCV), mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were not affected by supplementation of yucca powder. However, haemoglobin (HB) concentration was slightly increased and mean corpuscular haemoglobin concentration (MCHC) was significantly increased by 200 ppm yucca powder supplementation to the diet.Öğe Effects of ascorbic acid on cadmium-induced oxidative stress and performance of broilers(Humana Press Inc, 2005) Erdogan, Z; Erdogan, S; Celik, S; Unlu, AThe effects of cadmium on performance, antioxidant defense system, liver and kidney functions, and cadmium accumulation in selected tissues of broiler chickens were studied. Whether the possible adverse effects of cadmium would reverse with the antioxidant ascorbic acid was also investigated. Hence, 4 treatment groups (3 replicates of 10 chicks each) were designed in the study: control, ascorbic acid, cadmium, and cadmium plus ascorbic acid. Cadmium was given via the drinking water at a concentration of 25 mg/L for 6 wk. Ascorbic acid was added to the basal diet at 200 mg/kg either alone or with cadmium. Cadmium decreased the body weight (BW), body weight gain (BWG), and feed efficiency (FE) significantly at the end of the experiment, whereas its effect on feed consumption (FC) was not significant. Cadmium increased the plasma malondialdehyde (MDA) level as an indicator of lipid peroxidation and lowered the activity of blood superoxide dismutase (SOD). Liver function enzymes, aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and gamma glutamyl transferase (GGT) activities were not changed by cadmium. Cadmium ingestion did not alter serum creatinine levels. Although the serum cadmium level was not elevated, cadmium mainly accumulated in the kidneys, liver, pancreas, and muscle. Ascorbic acid supplementation resulted in a reduction of MDA level previously increased by cadmium and a restoration in SOD activity. However, ascorbic acid did not ameliorate the growth inhibitory effect of cadmium nor did it prevent accumulation of cadmium in analyzed tissues. These data indicate that oxidative stress induced by cadmium, plays a role in decreasing the performance of broilers and that dietary supplementation by ascorbic acid might be useful in reversing the lipid peroxidation induced by cadmium and partly alleviating the adverse effect of cadmium on performance of broilers.Öğe The effects of dietary lead exposure and ascorbic acid on performance, lipid peroxidation status and biochemical parameters of broilers(Tubitak Scientific & Technological Research Council Turkey, 2005) Erdogan, Z; Erdogan, S; Aksu, T; Baytok, ELead is one of the ubiquitous environmental pollutants that induce a broad range of physiological and biochemical dysfunctions in animals. This study evaluated the effects of dietary lead exposure and ascorbic acid on performance, serum biochemical parameters, plasma malonclialdehyde and lead accumulation in broiler chickens. For this purpose, lead acetate at 200 mg/kg and ascorbic acid at 100 mg/kg were added to the diet alone or in combination for 42 days. A total of 120 broiler chicks were divided into 4 treatment groups: control, ascorbic acid, lead, and lead + ascorbic acid. By the end of the study, lead caused body weight and body weight gain to decrease significantly, although its effects on feed consumption and the feed conversion ratio were not significant. While lead did not alter the serum lactate dehydrogenase, aspartate aminotransferase or alanine aminotransferase activities or albumin or total protein concentrations, it increased malondialdehyde (P < 0.001) and triglyceride (P < 0.01) levels. Although the lead contents of the serum and muscle were unchanged, lead was accumulated in the liver and kidneys (P < 0.001). Our results showed that lead (200 mg/kg diet) had an inhibitory effect on the growth of broilers and appeared to be inducing lipid peroxidation. The addition of ascorbic acid to the diet reduced the plasma malondialdehyde levels induced by lead and tended to reduce the inhibitory effect of lead on growth. It is concluded that the addition of higher doses of ascorbic acid to the diet may be more efficacious in fully reversing the negative effect of lead on growth.Öğe Efficacy of tribasic copper chloride (TBCC) to reduce the harmful effects of aflatoxin in broilers(Tubitak Scientific & Technological Research Council Turkey, 2005) Çelík, S; Erdogan, Z; Erdogan, S; Bal, RThis study was conducted to evaluate the effects of copper as tribasic copper chloride on serum biochemical values and growth performance of broilers intoxicated with aflatoxins. Aflatoxins significantly decreased the level of albumin (P < 0.001), total protein (P < 0.001) and total cholesterol (P < 0.01), and increased the activities of alanine amino transferase, L-lactic dehydrogenase and alkaline phosphatase (P <= 0.001) in serum. These AF-induced changes were significantly improved by adding tribasic copper chloride to the diet. The decrease in serum copper concentration induced by aflatoxin was reversed by tribasic copper chloride. Serum zinc concentrations were not affected in tribasic copper chloride and tribasic copper chloride plus aflatoxin groups. Serum iron levels decreased in all the treatment groups significantly (P < 0.05). Aflatoxins caused significant decrease in the body weight gain and significant increase in the feed conversion ratio. Adverse effects of aflatoxins on feed conversion ratio were reversed by tribasic copper chloride supplementation to the diet. It is suggested that tribasic copper chloride might be used for reducing the adverse effects of aflatoxins in broiler production.Öğe Seasonal and locational effects on serum, milk, liver and kidney chromium, manganese, copper, zinc, and iron concentrations of dairy cows(Humana Press Inc, 2004) Erdogan, S; Celik, S; Erdogan, ZChromium (Cr), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations were quantified in serum (n = 112), milk (n =: 112), liver (n = 70), and kidney samples (n = 67) of dairy cows from an iron-steel processing region (Payas-Iskenderun) and from an area free of industrial pollution (Antakya) in Hatay, located in Southern Turkey. Samples were collected in the summer and winter and element determinations were carried out by inductively coupled plasma-atomic emission spectrometry. The mean concentrations of selected elements in serum were found to be similar in both regions. Milk samples collected from the nonindustrial region in the summer had higher Cr, Mn, and Zn concentrations than the polluted region. The liver Cu and kidney Mn levels of samples taken from the industrial region in winter were higher than samples of the unpolluted region. Copper and Fe concentrations in milk, Cr, Mn, Zn, and Fe levels in the liver, and Cr, Cu, Zn, and Fe levels in kidney samples were not found to be different among the regions in both seasons. Copper concentrations were below the critical level in the 25% of serum and 32% of liver samples analyzed in this study. Fifteen percent of serum samples and most of the liver samples had lower amounts of Zn than other reported studies. Although slight differences were observed between the industrial and nonindustrial regions, industrial activities and seasonal changes had no significant effect on selected element concentrations on cows and their milk.Öğe Some mineral substance levels in serum of sheep and goat grazing in Hatay region(Tubitak Scientific & Technological Research Council Turkey, 2002) Erdogan, S; Ergün, Y; Erdogan, Z; Kontas, TThis study was carried out on 93 sheep and 92 goats which were all clinically healthy and raised in the pasture conditions in the Hatay region. Blood samples were collected from the jugular vein between June and July (1999) in Altinozu, Reyhanli, Yayladagi, Samandagi and Dortyol province. Serum samples were analysed by atomic absorption spectrophotometry for copper and zinc. Sodium and potassium levels were determined by flame photometry, calcium levels were quantified by Eppendorf photometry, magnesium was measured by spectrophotometry and selenium was determined by fluorometry. In the Hatay region, Mg 1.08 +/- 0.02 mmol/L, Ca 2.38 +/- 0.06 mmol/L, Na 149.07 +/- 2.06 mmol/L, K 3.05 +/- 0.07 mmol/L, Cu 0.32 +/- 0.01 ppm, Zn 0.22 +/- 0.01 ppm and Se 0.12 +/- 0.01 ppm were found in sheep; Mg 1.13 +/- 0.02 mmoI/L, Ca 2.11 +/- 0.05 mmoIIL, Na 149.37 +/- 2.65 mmol/L, K 3.06 +/- 0.05 mmol/L, Cu 0.33 +/- 0.02 ppm, Zn 0.21 +/- 0.00 ppm and Se 0.16 +/- 0.00 ppm were measured in goats. Calcium, Mg, Na and Se levels were found to be within the normal range in both sheep and goats. However, K levels were slightly lower in some regions, and Cu and Zn levels were under critical levels in all regions. It is concluded that Cu and Zn should be added to the rations of goats and sheep.