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    Predictors of improvement in left ventricular function after stent implantation of chronic coronary occlusion
    (2009) Akgül, Ferit; Batyraliev, Talantbek; Karben, Zarema; Serçelik, Alper; Vural, Aytaç; Fettser, Denis
    The effect of coronary stent implantation on left ventricular (LV) performance in patients with chronic coronary occlusion is not well known. The aim of this study was to assess the effect of bare metal and drug eluting stents implantation on LV ejection fraction (LVEF) and to examine what clinical and angiographic factors may have an effect on recovery of LVEF. Three hundred and four patients who underwent successful stent implantation for chronic occlusion of a major epicardial coronary artery existing for at least one month were included into the study. Echocardiographic examination was performed before and six months after stent implantation. A significant increase in LVEF (53.2±11.9% to 57.0±11.1%; p <0.0001) with a decrease in both LV end-diastolic volume index (85.6±18.9 ml/m2 to 80.1±17.1 ml/m2; p <0.001) and LV end-systolic volume index (40.0±15.8 ml/m2 to 34.1±14.3 ml/m2; p <0.0001) after stent implantation of chronic coronary occlusion was observed in the entire group. There was no significant difference in the increase of LVEF between bare metal stent and drug eluting stent groups. Multivariate analysis revealed that baseline LVEF 50%, occlusion duration <2 months and diabetes mellitus to be independent predictors of improvement in LVEF. Stent implantation for a chronic coronary occlusion has a beneficial effect on LVEF during the first 6 months after the stent implantation, especially in patients with depressed LV function and occlusion duration <2 months.