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Öğe Antioxidant effect of erdosteine and lipoic acid in ovarian ischemia-reperfusion injury(Elsevier Science Bv, 2014) Dokuyucu, Recep; Karateke, A.; Gokce, H.; Kurt, R. K.; Ozcan, O.; Ozturk, S.; Tas, Z. A.Objective: To investigate the effects of erdosteine and alpha lipoic acid (ALA) in a rat model of ovarian ischaemia-reperfusion injury. Study design: Forty-eight female Wistar albino rats were separated, at random, into six groups of eight rats. The groups were classified as: sham, torsion, detorsion, detorsion + erdosteine 100 mg/kg, detorsion + alpha lipoic acid (ALA) 100 mg/kg, and detorsion + erdosteine + ALA. The investigators executing the biochemical and histological analyses were blinded to the randomization until the end of the study. Results: The TOS (Total Oxidant Status) and OSI (Oxidative Stress Index) levels are higher in the Torsion and Detorsion groups when compared with the ones in the Sham group (p < 0.05). Strong correlation was found between OSI and total histological score in the sham, torsion and detorsion groups (r = 0.765, p < 0.001). The mean levels of TOS and OSI in the rats that received erdosteine and/or ALA were significantly lower compared with the sham, torsion and detorsion groups (p < 0.05). Mean TOS and mean OSI were lower in the detorsion + erdosteine + ALA group compared with the detorsion + erdosteine and detorsion + ALA groups (p < 0.05). In comparison with the detorsion group, the numbers of primordial follicles (p = 0.006) and primary follicles (p = 0.036) were increased in the groups that received erdosteine and/or ALA. Conclusions: Erdosteine and ALA decreased ischaemia-reperfusion injury in an experimental rat ovarian torsion model; combination treatment had a greater effect than either agent alone. Treatment with erdosteine and/or ALA was found to preserve the loss of reproductive capacity normally observed after ovarian torsion. (C) 2014 Elsevier Ireland Ltd. All rights reserved.Öğe Cytological, histopathological and clinical correlation at differential diagnosis of granulomatous mastitis-malignancy(Springer, 2012) Ozgur, T.; Atik, E.; Toprak, S.; Gokce, H.; Sengul, N.; Temiz, M.[Abstract Not Available]Öğe Dermoid cyst: A rare entity of the parotid gland(Springer, 2013) Toprak, S.; Ozgur, T.; Gokce, H.; Cevik, C.; Akbay, E.; Atik, E.[Abstract Not Available]Öğe Gemistocytic astrocytoma with granulomatous inflammation(Springer, 2012) Ipci, O.; Dogan, E. Atik; Ozgur, T.; Gokce, H.; Yilmaz, N.; Yilmaz, A.[Abstract Not Available]Öğe Inverted papilloma with squamous cell carcinoma(Springer, 2012) Ozgur, T.; Toprak, S.; Atik, E.; Gokce, H.; Okuyucu, S.[Abstract Not Available]Öğe Irreversible Horner's syndrome diagnosed by aproclonidine test due to benign thyroid nodule(Professional Medical Publications, 2013) Coskun, M.; Aydogan, A.; Gokce, C.; Ilhan, O.; Ozkan, O., V; Gokce, H.; Oksuz, H.We are reporting an irreversible Horner Syndrome (HS) in a patient with benign thyroid gland nodule in which thyroidectomy was performed for treatment. A 37-year-old female was admitted to our clinic with a swelling in the left lobe of the thyroid gland and ptosis at the left eyelid. The clinical diagnosis of HS was confirmed pharmacologically by aproclonidine. Histopathologic examination of thyroidectomy specimen was reported as benign nodule. To the best of our knowledge, this is a very rare report in terms of thyroid benign nodule associated with irreversible HS due to cervical sympathetic chain compression.Öğe Myoepithelioma of tongue(Springer, 2012) Gokce, H.; Ipci, O.; Atik, E.; Ozgur, T.; Akbay, E.[Abstract Not Available]Öğe Twin reverse arterial perfusion syndrome: A case report(Springer, 2013) Toprak, S.; Atik, E.; Okyay, A. G.; Ipci, O.; Ozgur, T.; Gokce, H.[Abstract Not Available]Öğe Umblical cord haemangioma: A case report(Springer, 2013) Ozgur, T.; Okyay, A. G.; Gokce, H.; Toprak, S.; Atik, E.[Abstract Not Available]
