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Öğe Is There any Significant Association Between Irritable Bowel Syndrome and Cholelithiasis ?(Aves, 2008) Kuvandik, G.; Helvaci, M. R.; Ozkan, O. V.; Sogut, S.; Kaya, H.; Bozkurt, S.Background: We tried to understand whether or not there is a significant etiopathogenetic relationship between irritable bowel syndrome (IBS) and cholelithiasis. Methods: Consecutive patients with upper abdominal discomfort were included into the study. Routine hematologic and biochemical tests, an abdominal ultrasonography, and a questionnaire for IBS was performed in all cases, and IBS is diagnosed according to Rome II criteria in the absence of red flag symptoms. Cholelithiasis cases were put into one group and age and sex-matched and randomly selected cases without cholelithiasis were put into the other group. Prevalences of smoking, normal weight, overweight, obesity, and IBS were detected in each group and compared in between. Results: One hundred and twenty-one patients with cholelithiasis were diagnosed. Ninety-seven (80.1%) of them were female, and their mean age was 53.4 +/- 9.9 (27-70) years. Interestingly, 92.5% (112 cases) of the cholelithiasis cases had excess weight and obesity was significantly higher in the cholelithiasis group (54.5% vs. 43.8%, p<0.05). Prevalence of IBS was nearly equal in both groups (43.8% in cholelithiasis vs. 42.1% in control cases, p>0.05). Conclusions: IBS probably is a cascade of many physiological events, being initiated with infection, inflammation, psychological disturbances-like stresses and eventually terminated with dysfunctions of genitourinary tract and probably some other systems of body via a low-grade inflammatory process. Although IBS probably has a much more complex mechanism than the current view and a higher prevalence in society, there is not a significant association between IBS and cholelithiasis.Öğe Reptile bite in pregnancy(Sage Publications Ltd, 2008) Duru, M.; Helvaci, M. R.; Peker, E.; Dolapcioglu, K.; Kaya, E.Reptile bites are rarely seen cases in emergency departments. But particularly in the warm summer months, the prevalence is relatively higher in rural areas. Snakebites during pregnancy is little known and only a few cases have been reported in the literature. However, in case of pregnancy, the outcomes may he different both for mother and the fetus. Interestingly, there is limited number of reptile bite cases during pregnancy in the literature. We report here a woman who was bitten at her 28th week of gestation. Obstetric consultation with ultrasonography was performed and seen that fetus was normal according to a 28-week gestation. We infused four vials of antiserum in a period of 1 h in a saline solution. In all, 30 min after the initiation of the antiserum infusion, the lesion started to regress. Her obstetric consultation was repeated 1 h, 36 h, and before discharge were performed and seen that the fetus was normal. After a period of five days, the patient and fetus were evaluated once more, and nothing was abnormal for both.Öğe Scorpion stings in pregnant women: an analysis of 11 cases and review of literature(7847050 Canada Inc, 2015) Kaplanoglu, M.; Helvaci, M. R.Scorpion sting is one of the most important public health problem in many regions of the world. But there is not enough medical data about scorpion stings in pregnant women in the literature. The aim of this study was to describe the clinical findings and treatment modalities of scorpion stings in pregnant women. This study was performed in the Southeast Region of Turkey, retrospectively. Eleven pregnants were studied, totally. All of the patients were detected as class I according to the scorpion envenomization system. They were in different weeks of gestation. Local pain, hyperemia, swelling, and itching were the most frequent complaint in these cases. None of our patients received antivenotn, and all of them were treated, symptomatically. Complication of pregnancy was observed in none of them.Öğe What is the relationship between type 2 diabetes mellitus and urolithiasis?(Comenius Univ, 2011) Davarci, M.; Helvaci, M. R.; Aydin, M.Aim: Despite the high incidence of urolithiasis in general population, the exact underlying pathology is unknown. Possible association between urolithiasis and parameters of physical health were assesed in the presented study. Material and methods: The study was performed at an Internal Medicine out patient unit during routine check ups. Patients between the ages of 20 and 70 years were studied to prevent debility induced weight loss in elderly. Patients with devastating illnesses were excluded to avoid their possible effects on weight. Cases with urolithiasis were collected in one group, and age and sex-matched cases without urolithiasis were collected in other group. Results: Eighty cases with urolithiasis and 120 cases without were studied. Mean age of urolithiasis cases was 49.0 years, and 52.5 % of them were female. Mean weight of the urolithiasis cases was 76.0 kg, whereas it was 80.8 kg in the group without urolithiasis (p=0.013). The prevalence of type 2 diabetes mellitus (DM) was significantly higher in the urolithiasis group with unknown reasons (17.5 % vs 7.5 %, p<0.01). There was no significant difference as for the height, body mass index, prevalence of hypertension, and mean values of low density lipoprotein cholesterol, high density lipoprotein cholesterol, and triglyceride between the groups. Conclusion: In spite of several terrible effects of excess weight on health, we could not detect any association with urolithiasis, but there is a highly significant association between urolithiasis and type 2 DM, and it may have hundreds of mechanisms with variable priorities, which must be explained with further studies (Tab. 1, Ref. 21). Full Text in free PDF www.bmj.sk.
