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Öğe Comparison of sub-tenon triamcinolone acetonide and intravitreal bevacizumab for the treatment of macular edema due to branch retinal vein occlusion(2013) Ilhan, Nilüfer; Ayhan Tuzcu, Esra; Da?lio?lu, Mutlu Cihan; Coşkun, Mesut; Ilhan, Özgür; Ayintap, Emre; Keskin, U?urcanPurpose: To evaluate the effect of subtenon triamcinolone acetonide (STA) and intravitreal bevacizumab (IVB) injections in the treatment of macular edema due to branch retinal vein occlusion (BRVO). Materials and Methods: In this retrospective study, 41 eyes of 41 patients with macular edema due to BRVO were included. The records of 21 patients of triamcinolone and 20 patients of bevacizumab group were analyzed retrospectively. Before injection and 1., 3. and 6 months after the treatment, best-corrected visual acuity (BCVA) (logMAR), intraocular pressure (IOP) and central foveal thickness (CFT) detected by optical coherence tomography were recorded. Results: In the triamcinolone group baseline values including BCVA (logMAR) and CFT were 0.94±0.42 logMAR and 552±70 ?m. In the bevacizumab group, they were 0.98±0.50 logMAR and 541±94 ?m. At 6th month BCVA and CFT were 0.57±0.35 logMAR and 342±34 ?m in the triamcinolone group whereas these values were 0.41±0.23 logMAR and 289±15?m in the bevacizumab group. During the follow up, the mean BCVA was not significantly different but the mean CFT was significantly different at 3rd and 6th month between groups. Five patients (23.8%) from triamcinolone group, IOP exceeded 24 mm Hg postoperatively. No complications observed in the bevacizumab group. Conclusion: The visual outcome of STA and IVB injections in patients with macular edema due to BRVO was similar. Increased IOP after injection limits the usage of STA. However the effect of IVB on the macular edema seems better than STA.Öğe Evaluation of retinal nerve fiber thickness by optic coherens tomography in smokers(Gazi Eye Foundation, 2015) Akarsu, Mustafa; Abit, Mahmut Sinan; Ilhan, ÖzgürPurpose: To investigate whether smoking cause any changes in number of ganglion cells, ganglion cell layer thickness and optic nerve head in healthy adults. Material and Methods: In the study volunteers aged from 20 to 50 who admitted to ophthalmology department of Mustafa Kemal University Faculty of Medicine between April 2013 and October 2013 were included; of which 73 were non smoker and 78 were smokers. Retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (Cirrus HD OCT); fast RNFL protocol was used. SPSS for Windows 13, 0 (Statistical Package for Social Sciences) was used for statistical analysis. Results: Upper quadrant thickness was 122.41±14.43 ?m in smokers and was 118.77±17.89 ?m in non smokers. Nasal quadrant thickness was 75.07±12.53 ?m in smokers and was 76.68±15.00 ?m in non smokers, lower quadrant thickness was 125.40±19.97 ?m in smokers and was 127.85±17.58 ?m in non smokers; there was no statistically significant difference in these groups. Temporal quadrant thickness was 68.10±9.74 ?m in smokers and was 72.40±10.80 ?m in non smokers and the difference was statistically significant. Upper, nasal, inferior, temporal quadrants and average RNFL values showed no statistically significant difference between mild, moderate or severe smokers subgroups. Conclusion: The study implies thinning of temporal quadrant RNFL thickness in smokers. This is likely to occur due to neurotoxic damage caused by smoking. It is advisable that heavy smokers should be cautioned for such a possible correlation and regularly followed-up.Öğe Optic nerve infarct following traumatic hyphema of sickle cell trait(2013) Tuzcu, Esra Ayhan; Çoskun, Mesut; Ilhan, Özgür; Ayintap, Emre; Keskin, U?urcan; Öksüz, HüseyinBlunt ocular trauma, eye surgery, pathologies of iris and situations that thrombocytopenia can cause to hyphema. From these causes the most common is blunt ocular trauma and it occurs commonly in children. Hypema may often be treated without any complications in the normal individuals. However vision threatening complications are common in hyphemas seen in patients with hemoglobinopathy. These complication include optic nerve damage due to high intraocular pressure, recurrent hyphema, obstruction in retinal vascularite and infarction of optic nerve. Optic nerve infarction is usually associated with retinal vein occlusion and intraocular pressure elevation. In this report, a case with optic nerve infarct resulted from hyphema which was caused by a minimal blunt trauma in a sickle cell trait child is presented.Öğe Results of pars plana capsulectomy and anterior vitrectomy in cases which nd:yag capsulotomy was inappropriate(2011) Ayintap, Emre; Coşkun, Mesut; Ilhan, Özgür; Keskin, U?urcan; Ayhan Tuzcu, Esra; ÖksüZ, HüseyinPurpose: To evaluate pars plana capsulectomy (PPC) and anterior vitrectomy (AV) results in posterior capsule opacification (PCO), which can develop after cataract surgery, in pediatric and adult patients in which Nd:YAG laser capsulotomy cannot be performed and/or is not effective because of dense thickening of the posterior capsule. Materials and Methods: Pediatric and adult patients with PPC and AV were included in the study in different groups retrospectively. Results: Nine eyes of 6 pediatric patients and 6 eyes of 6 adults were included in the study. Mean age was 6.1 years (1-11) in the pediatric patients and 59.25 (23-80) in the adults. The mean period of PCO development was 7.6 months in the pediatric patients and 48.2 (2-60) months in the adults. In 7 eyes of 5 pediatric patients who were able to express visual acuity, preoperative best corrected visual acuity (BCVA) was logmar 1.16±0.44 (1-1.6) (Snellen equivalent SE: 0.05-0.1), while it was logmar 0.54±0.26 (0.2-1) (SE: 0.25-0.3) postoperatively. In adults preoperative BCVA was logmar 1.28±0.32 (1-1.6) (SE: finger counting at 3 meters) and it was logmar 0.80±0.2 (0.2-1) (SE: 0.16) postoperatively. At postoperative day one and at 13.6 months mean follow up, a clear optic axis and increase in BCVA were achieved in all eyes. Conclusion: PPC with AV is a preferable management when Nd:YAG laser capsulectomy cannot be performed and/or with the presence of very severe capsule thickening or in cases with cortex reminant on capsule and in cases in which Nd:YAG laser capsulotomy is not effective. We think that performing nearly 5-mm diameter posterior capsulectomy is an important factor in obtaining long period success.
