Yazar "Inanoglu, Kerem" seçeneğine göre listele
Listeleniyor 1 - 11 / 11
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe The analgesic efficacy of preoperative versus postoperative lornoxicam in varicocele repair(Elsevier Science Inc, 2007) Inanoglu, Kerem; Gorur, Sadik; Akkurt, Cagla Ozbakis; Guven, Oguz E.; Kararmaz, AlperStudy Objective: To determine whether intravenous injection of lornoxicam 30 minutes before skin incision provides better pain relief after varicocelectomy than postoperative administration of lornoxicam. Design: Prospective, double-blind, randomized clinical investigation. Setting: Operating room and postoperative recovery area. Patients: 44 ASA physical status I and 11 adult male patients undergoing varicocelectomy. Interventions: Patients were randomized either to receive 8 mg lornoxicam infusion 30 minutes before skin incision, followed by saline infusion immediately after skin closure (group 1), or to receive the identical injections but in reverse order (group 2). All patients received local anesthesia with bupivacame. Measurements: Postoperative pain scores were evaluated hourly for the first 8 hours after surgery, then at 12, 16, 20, and 24 hours after surgery, using a 10-cm visual analog scale. Time to first analgesic request and patient's global assessments also were recorded. Main Results: Patients in group 1 reported significantly lower pain scores (P < 0.05) at all time intervals except at 24 hours and better global assessment (P = 0.001) than did group 2. There were significantly fewer patients in the preemptive group than group 2 who required rescue analgesic within the first 24 hours (0% vs 22.7%; P = 0.024). Mean time to first analgesic request was also significantly longer in the preemptive group (P = 0.001). Conclusion: Intravenous lornoxicam administered before surgery has a better analgesic effect for varicocelectomy than when administered postoperatively. (c) 2007 Elsevier Inc. All rights reserved.Öğe Comparison of Ketoprofen Phonophoresis with Ketoprofen and Lidocaine-Prilocaine Phonophoresis in Patients with Subacromial Impingement Syndrome(Turkish League Against Rheumatism, 2009) Guler, Hayal; Turhanoglu, Ayse Dicle; Inanoglu, Kerem; Inanoglu, Deniz; Ozer, CahitObjective: The aim of the present study was to compare ketoprofen phonophoresis with ketoprofen and lidocaine-prilocaine phonophoresis in patients with subacromial impingement syndrome (SIS). Material and Methods: Seventy patients (39 female, 31 male) with SIS were included in this study. The patients were divided into two groups and a 15-session physical therapy and rehabilitation program was performed in each group. Ketoprofen and lidocaine-prilocaine phonophoresis were performed in the first group and ketoprofen phonophoresis alone in the second group. Hot pack, transcutaneous electrical nerve stimulation (TENS) and exercises were applied in all patients. Severity of shoulder pain was determined by visual analogue scale (VAS). Range of motion (ROM) was measured by goniometer. Functional capacity of patients was evaluated by UCLA (The University of California-Los Angeles) score. All of the measurements were performed before treatment and in the 1st and 3rd months after treatment. Results: There was no significant difference between the two groups in VAS and UCLA scores before treatment initiation (p>0.05). VAS scores of Group 1 were lower than of Group 2 (p=0.020) in the 3rd month follow-up. ROMs and flexion, abduction and internal rotation were higher in Group 2 than Group 1 (p=0.009, p=0.001, p=0.019, respectively) before treatment. Abduction measurements in Group 2 were higher than in Group 1 in the 1st month after treatment (p=0.024). However, there was no significant difference between the two groups in UCLA and ROM values in the 3rd month (p>0.05). There was also no significant difference between the two groups in external rotation values before and after treatment (p>0.05). Conclusion: Our study showed that ketoprofen and lidocaine-prilocaine phonophoresis were more effective on pain and ROM than ketoprofen phonophoresis alone in the 3rd month after treatment in patients with SIS. (Turk J Rheumatol 2009; 24: 88-93)Öğe Comparison of Recovery Characteristics, Postoperative Nausea and Vomiting, and Gastrointestinal Motility With Total Intravenous Anesthesia With Propofol Versus Inhalation Anesthesia With Desflurane for Laparoscopic Cholecystectomy: A Randomized Controlled Study(Elsevier Science Inc, 2009) Akkurt, B. Cagla Ozbakis; Temiz, Muhyittin; Inanoglu, Kerem; Aslan, Ahmet; Turhanoglu, Selim; Asfuroglu, Zeynel; Canbolant, ElifBACKGROUND: Clinical effects, recovery characteristics, and costs of total intravenous anesthesia with different inhalational anesthetics have been investigated and compared; however, there are no reported clinical studies focusing on the effects of anesthesia with propofol and desflurane in patients undergoing laparoscopic cholecystectomy. OBJECTIVE: The aim of this study was to determine the effects of total intravenous anesthesia with propofol and alfentanil compared with those of desflurane and alfentanil on recovery characteristics, postoperative nausea and vomiting (PONV), duration of hospitalization, and gastrointestinal motility. METHODS: Patients classified as American Society of Anesthesiologists physical status I or II undergoing elective laparoscopic cholecystectomy due to benign gallbladder disease were enrolled in the study. Patients were randomly assigned at a 1:1 ratio to receive total intravenous anesthesia with propofol (2-2.5 mg/kg) and alfentanil (20 mu g/kg) or desflurane (4%-6%) and alfentanil (20 mu g/kg). Perioperative management during premedication, intraoperative analgesia, relaxation, ventilation, and postoperative analgesia were carried out identically in the 2 groups. Extubation time, recovery time, PONV, postoperative antiemetic requirement, time to gastrointestinal motility and flatus, duration of hospitalization, and adverse effects were recorded. Postoperative pain was assessed using a visual analogue scale. RESULTS: Sixty-eight patients were assessed for inclusion in the study; 5 were excluded because they chose open surgery and 3 did not complete the study because they left the hospital. Sixty patients (33 women, 27 men) completed the study. Recovery time was significantly shorter the propofol group (n = 30) compared with the desflurane group (n = 30) (8.0 [0.77] vs 9.2 [0.66] min, respectively; P < 0.005). Fifteen patients (50.0%) in the propofol group and 20 patients (66.7%) in the desflurane group experienced nausea during the first 24 hours after surgery. The difference was not considered significant. In the propofol group, significantly fewer patients had vomiting episodes compared with those in the desflurane group (2 [6.7%] vs 16 [53.3%]; P < 0.005). Significantly fewer patients in the propofol group required analgesic medication in the first 24 hours after surgery compared with those in the desflurane group (10 [33.3%] vs 15 [50.0%]; P < 0.005). Patients in the propofol group experienced bowel movements In a significantly shorter period of time compared with patients in the desflurane group (8.30 [1.67] vs 9.76 [1.88] hours; P = 0.02). The mean time to flatus occurred significantly sooner after surgery in the propofol group than in the desflurane group (8.70 [1.79] vs 9.46 [2.09] hours; P = 0.01). The duration of hospitalization after Surgery was significantly shorter in the propofol group than in the desflurane group (40.60 [3.49] vs 43.60 [3.56] hours; P = 0.03). CONCLUSION: Total intravenous anesthesia with propofol and alfentanil was associated with a significantly reduced rate of PONV and analgesic consumption, shortened recovery time and duration of hospitalization, accelerated onset of bowel movements, and increased patient satisfaction compared with desflurane and alfentanil in these patients undergoing laparoscopic surgery who completed the study. (Curr Ther Res Clin Exp. 2009;70:94-103) (C) 2009 Excerpta Medica Inc.Öğe The effect of anesthetic agents on perioperative bleeding during tonsillectomy: Propofol-based versus desflurane-based anesthesia(Mosby-Elsevier, 2008) Okuyucu, Semsettin; Inanoglu, Kerem; Akkurt, Cagla Ozbakis; Akoglu, Ertap; Dagli, SafakOBJECTIVE: Hemorrhage during tonsillectomy is related to the surgical technique, management of bleeding, and choice of anesthetic agent. This study evaluated the effects of anesthetic agents on hemorrhage during tonsillectomy with standardized surgical techniques and management of bleeding. STUDY DESIGN: Double-blind, randomized controlled trial. SUBJECTS AND METHODS: Sixty patients, aged 3 to 12 years, who were scheduled for elective tonsillectomy were enrolled in the study. Propofol-based anesthesia was administered to the first group; desflurane-based anesthesia, to the second. The amount of blood loss due to hemorrhage was measured. RESULTS: Propofol-based anesthesia significantly decreased bleeding during tonsillectomy. CONCLUSION: Propofol-based anesthesia is a reliable method for use in children who undergo tonsillectomy. (C) 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.Öğe Effects of Intravenous Small Dose Ketamine and Midazolam on Postoperative Pain Following Knee Arthroscopy(Wiley, 2009) Akkurt, Buket Cagla Ozbakis; Inanoglu, Kerem; Kalacı, Aydıner; Turhanoglu, Selim; Asfuroglu, Zeynel; Tumkaya, FerayBackground: The aim of this randomized, double blind, controlled study was to assess the effect of intravenous coadministration of small dose midazolam with ketamine on postoperative pain and spinal block level. Methods: Sixty patients undergoing arthroscopic knee surgery under spinal anesthesia were randomized into three groups: Group I (saline control); group II (ketamine 0.15 mg/kg i.v.); and group III (ketamine 0.15 mg/kg + midazolam 0.01 mg/kg i.v.). Sedation scores, visual analogue scores, time to first postoperative analgesic, total meperidine consumption, patient satisfaction, sensory and motor block levels, and two segments regression times were assessed. Results: Sedation scores were significantly lower in group I when compared with groups II and III at 1, 3, 5, and 10 minutes after administration of the spinal anesthetic (P = 0.001). Sensory block was significantly higher in group III (P = 0.001) in comparison with group II. Two segment regression time was significantly longer in group II than group I, whereas no difference was found between groups II and III. Total meperidine consumption was significantly higher in group I (P = 0,001). Patient satisfaction was significantly higher in group III compared with group I (P = 0.001), but no difference was found between groups II and III (P = 0.3). Conclusion: Ketamine improved the postoperative pain patient satisfaction, increased the maximal sensory level, and was associated with lower sedation scores in the first 15 minutes after administration. Group I was also associated with decreased total meperidine consumption and delayed the time to first recue analgesic administration. Coadministration of ketamine and midazolam did not provide any further benefit over ketamine alone.Öğe Epidural ropivacaine versus ropivacaine plus tramadol in postoperative analgesia in children undergoing major abdominal surgery: a comparison(Springer Tokyo, 2010) Inanoglu, Kerem; Ozcengiz, Dilek; Gunes, Yasemin; Unlugenc, Hakki; Isik, GeylanIn this study, we aimed to compare the effects of ropivacaine alone and ropivacaine plus tramadol administered epidurally for postoperative analgesia in children. Following Ethics Committee approval and informed parent consent, 44 children aged between 2 and 12 years, with ASA physical status I or II, who were undergoing major abdominal surgery were included in the study. Following tracheal intubation, patients were placed into lateral decubitus position and an epidural catheter (22-24 G) was inserted by using a Tuohy needle. Patients were randomly divided into two groups to receive either ropivacaine alone (0.2%), 0.7 ml/kg, in group I, or ropivacaine (0.2%) plus tramadol (2 mg/kg), with total volume 0.7 ml/kg, in group II, epidurally in both groups. Hemodynamic variables, pain and sedation scores, duration of analgesia, and side effects were recorded postoperatively. The duration of analgesia was significantly longer in group RT than in group R (298.6 +/- A 28 and 867.9 +/- A 106.8 min in group I and II, respectively) (P < 0.05). CHEOPS scores were significantly lower in group RT at 30 min, 45 min, and 3 h postoperatively than in group R (P < 0.05). However, sedation scores were similar between the two groups. Twenty-two patients (100%) in group R and 13 patients (59%) in group RT needed supplemental analgesia postoperatively. There were no significant differences in side effects between the groups. In children undergoing major abdominal surgery, epidural tramadol, added to epidural ropivacaine, provided lower pain scores, longer duration of analgesia, and lower postoperative analgesic requirement.Öğe Intravenous ketamine and local bupivacaine infiltration are effective as part of a multimodal regime for reducing post-tonsillectomy pain(Int Scientific Information, Inc, 2009) Inanoglu, Kerem; Akkurt, B. Cagla Ozbakis; Turhanoglu, Selim; Okuyucu, Semsettin; Akoglu, ErtapBackground: The aim of this study was to investigate the effects of a multimodal analgesic regimen, including intravenous ketamine and peritonsillar infiltration of bupivacaine, on post-tonsillectomy pain in children. Material/Methods: Ninety children aged 2-12 years, undergoing tonsillectomy, were enrolled in this randomized, controlled and double-blinded study. Group I (n=30) received intravenous and peritonsillar saline, group II (n=30) received intravenous saline and peritonsillar bupivacaine, and group III (n=30) received intravenous 0.5 mg/kg ketamine and peritonsillar 0.25% bupivacaine (3-5 ml per tonsil). Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24 h postoperatively. Results: No difference was found in the demographic data among the groups. Group I patients who received intravenous and peritonsillar saline solution as placebo had higher pain scores at 15(th) min, and Ist and 4(th) h than group II, and at all time intervals, than group III (P<0.05). Patients in group III also had significantly lower pain scores than group II at all time intervals except at 15(th) min (P<0.05). Analgesic requirements and the time to first analgesia were also significantly (P<0.05) better in the ketamine group. Conclusions: Intravenous ketamine and peritonsillar infiltration with bupivacaine are safe and effective as part of a multimodal regime in reducing post-tonsillectomy pain.Öğe Negative pressure pulmonary edema (NPPE) after discectomy in general anesthesia with endotracheal intubation: Case report(2006) Akkurt, B. Cagla O.; Kararmaz, Alper; Inanoglu, Kerem; Serarslan, YurdalBackground: Negative-pressure pulmonary edema (NPPE) is a rare and serious complication after general anesthesia. Although it is generally seen after upper airway surgery, it can be seen in different types of surgery also. We report a young, healthy case that developed pulmonary hemorrhage and alveolar edema after extubation of the trachea. Case Report: A 27-year-old ASA II male with a history of smoking, underwent elective discectomy. Following uneventful surgery under general anesthesia, the patient was taken to supine position. He developed a marked inspiratory effort and he bit the endotracheal tube during position changing. Immediately after extubation, the patient developed respiratory distress. Due to desaturation the patient was reintubated An intense hemorrhagic fluid was suctioned in the endotracheal tube. The chest radiograph showed bilateral pulmonary infiltrates. After 24 hours of mechanical ventilation, the patient's symptoms improved and he was extubated. He was discharged from the hospital on the fourth postoperative day. Conclusions: Although it is rare, NPPE can be seen following operations other than upper airway surgery.Öğe Periprostatic nerve blockage reduces postoperative analgesic consumption and pain scores of patients undergoing transurethral prostate resection(Karger, 2007) Gorur, Sadik; Inanoglu, Kerem; Akkurt, B. Cagla O.; Candan, Yasar; Kiper, Ahmet N.Introduction: To evaluate the effects of periprostatic bupivacaine administration on pain control and analgesic consumption after transurethral prostate resection (TURP). Materials and Methods: The study included 40 male patients with benign prostatic hyperplasia who underwent TURP, and they were divided randomly into two groups. All patients were operated under general anesthesia. The study group patients (n = 20) received periprostatic bupivacaine (0.5% 20 ml) injection (group I), and the control patients (n = 20) received only saline (NaCl 0.9% 20 ml) injection (group II). All injections were performed bilaterally into the periprostatic areas immediately after the TURP procedure via the transperineal route. In the postoperative period, all patients (groups I and II) received tramadol using a patient-controlled analgesia device. Postoperative pain was assessed and recorded using the visual analog scale (VAS) at postoperative hours 1, 2, 3, 4, 5, 6, 7, 8, 12, 16, 20, 24, and 48. Total tramadol consumptions and additional analgesic requirements were also recorded and compared between groups. Results: There was no difference in demographic data between the two groups (p > 0.05). VAS scores of the patients at hours 1, 3, 4, 5, 7, 8, and 12 were found to be significantly lower in group I than in group II (p < 0.05). Total tramadol consumption and patient-controlled analgesia demands of groups I and II were 153.5 +/- 8 52.4 vs. 465.0 +/- 55.1 mg and 17.1 +/- 7.7 vs. 77.8 +/- 7.5 mg, respectively (p < 0.001). No side effect was observed regarding bupivacaine injections. Conclusions: Periprostatic bupivacaine administration was a useful and safe method for postoperative pain control and reduced analgesic consumption in patients undergoing TURP. Copyright (c) 2007 S. Karger AG, Basel.Öğe Ropivacaine compared to bupivacaine for post-tonsillectomy pain relief in children: A randomized controlled study(Elsevier Ireland Ltd, 2006) Akoglu, Ertap; Akkurt, B. Cagla Ozbakis; Inanoglu, Kerem; Okuyucu, Semsettin; Dagli, SafakObjective: To compare the effects of ropivacaine and bupivacaine on post-tonsillectomy pain in children. Methods: Forty-six children aged 2-12 years, undergoing tonsillectomy were enrolled in the study. Group 1 (n = 16) received bupivacaine, group 2 (n = 15) received ropivacaine, and a group 3 (control) (n = 15) received 9% NaCl (saline) infiltrated around each tonsil. Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24 h postoperatively. Results: No difference was found in the demographic data among the groups. The pain scores were similar between the bupivacaine and ropivacaine groups (p > 0.05). The pain scores in both analgesia groups were significantly (p < 0.05) lower 1, 4, 12, 16, and 24 h postoperatively compared to the control group. Analgesic requirements and the time to first analgesia were also significantly (p < 0.05) different between the analgesia and control groups. Conclusion: Local ropivacaine infiltration is a safe and effective method and equivalent to bupivacaine for post-tonsillectomy pain. (C) 2005 Elsevier Ireland Ltd. All rights reserved.Öğe Spinal anesthesia in a patient with cerebral manifestations of Wilson's Disease: case report(Int Scientific Literature, Inc, 2008) Inanoglu, Kerem; Akkurt, Cagla Ozbakis; Kalacı, Aydıner; Asfuroglu, Zeynel; Turhanoglu, SelimBackground: Wilson's disease is a rare autosomal recessive genetic disorder of copper metabolism and patients with Wilson's or other severe liver diseases are at risk when undergoing anesthesia and surgery. Case Report: We report the case of a neurologically impaired (lack of motor coordination, spasticity and dystonia of all four limbs, and drooling) 18-year-old male who was diagnosed with Wilson's disease 5 years earlier. He underwent intramedullary nailing for femoral fracture with spinal anesthesia and no complication was observed. Conclusions: In patients with cerebral manifestations of Wilson's disease, in appropriate surgical procedures spinal anesthesia may be used as the anesthesia method.
