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Öğe Aşım sezonunda FGA ile senkronize edilen ivesi koyunlarında PGF2a ve PMSG uygulamasının bazı reprodüktif parametreler üzerine etkisi(2017) Akbaş, Ömer Faruk; Köse, Ayşe MerveAkbaş ÖF, Köse AM. Aşım sezonunda FGA ile senkronize edilen ivesi koyunlarında PGF2? ve PMSG uygulamasının bazı reprodüktif parametreler üzerine etkisi.Amaç: Çalışma, üreme sezonunda fluorogeston asetat içeren vaginal süngerler ile senkronize edilmiş İvesi ırkı koyunlarda, süngerlerin çıkartıldığı gün uygulanan PMSG ve PGF2?'nın fertilite parametreleri üzerindeki etkilerini karşılaştırmak amacıyla düzenlendi.Gereç ve Yöntem: Araştırmada 75 baş koyun kullanıldı. Koyunların tamamına 20 mg FGA içeren vaginal süngerler 10 gün süreyle uygulandı. Süngerlerin çıkartıldığı gün FGA I (n:25) grubundaki koyunlara herhangi bir enjeksiyon yapılmadı. FGA II (n:25) grubundaki hayvanlara 125 mcg cloprostenol, FGA III (n:25) grubundakilere ise 500 IU PMSG ile 125 mcg cloprostenol kas içi olarak uygulandı. Bulgular: FGA I, FGA II ve FGA III gruplarında östrüs başlangıç zamanları sırasıyla 52.36±2.91, 38.53±2.53 ve 31.30±1.96 saat olarak belirlendi. FGA I, FGA II ve FGA III gruplarında östrüs oranları sırasıyla %88, %72 ve %88, gebelik oranları %64, %60 ve %84, konsepsiyon oranları %72.7, %83.3 ve %95, abort oranları %18.75, %33.3 ve %28.6, ikizlik oranları %12.5, %6.6 ve %28.5, doğum oranları %81.25, %66.6 ve %71.4, yavru verimleri ise %115.3, %110 ve %140 olarak saptandı. Gruplar arasında östrüs başlangıç zamanı açısından istatistik fark belirlenirken (P<0.001) diğer parametreler arasında istatistik fark belirlenemedi (P>0.05)Öğe Bir köpekte vajinal leyomiyosarkom(2017) Köse, Ayşe Merve; Özsoy, Şule Yurdagül; Doğruer, GökhanBu olguda kısırlaştırılmış bir köpekte vajinal leyomiyosarkomun tanımlanması amaçlanmıştır. Olgunun materyalini vulvasından sarkan bir kitle şikayeti ile kliniğimize getirilen melez erişkin dişi bir köpek oluşturdu. Köpeğin anamnez bilgilerinde daha önce kısırlaştırılmış olduğu ve son iki aydır vulvasından sarkan bir kitlenin olduğu öğrenildi. Fiziksel muayenede köpeğin genel durumunun iyi olduğu belirlendi. Vajinal muayenede; vulvadan dışarı sarkan, saplı, pembemsi renkli sert bir kitle tespit edildi. Kitlenin köpeğin vajinasının dorsal duvarından köken aldığı belirlendi. Kitleye tümöral bir yapı tanısı konularak operasyonla uzaklaştırılmasına karar verildi. Makroskobik olarak 5.6x3.2x1.7 cm boyutlarında, 43 gr ağırlığında, pembemsi beyaz renkte, elastik kıvamlı kitle gözlendi. Mikroskobik olarak hiperkromatik çekirdekli, birbirine çaprazlar yapan, anaplastik şekilli, iğsi ve yuvarlak şekilli hücreler arasında çok çekirdekli dev hücreleri, nekroz alanları ve yer yer mitozlar dikkati çekti. Makroskobik ve mikroskobik özelliklerine göre tümöre leyomiyosarkom tanısı kondu. Sonuç olarak; vajinal leyomiyosarkomun köpeklerde nadir görülmesi ve köpeğin kısırlaştırılmış olması nedeniyle olgunun makroskobik ve histopatolojik bulgularının literatür verilere katkı sağlayabileceği düşünüldü.Öğe Determination of efficient CIDR application periods in timed artificial insemination of Damascus goats during the breeding season(Ankara Üniversitesi, 2019) Doğruer, Gökhan; Karaca, Fikret; Yoldaş Ürer, Ece; Köse, Ayşe Merve; Ateş, Cafer Tayyar; Özcan, Oğuzhan; Sarıbay, Mustafa KemalThis research was conducted to determine the most efficient CIDR application periods in timed artificial insemination (TAI) protocols in Damascus goats during the breeding season. Ninety-six Damascus goats were used and the animals were randomly allocated into four equal groups. CIDR was used for 18, 12, 6 and 3 days in groups VL, L, S, and VS, respectively. 500 IU of eCG and 125 mcg of cloprostenol were administered on the day of CIDR removal. The goats were timely inseminated intra-cervically by cooled semen 48-60 h after removal of CIDR together with 5 mcg GnRH administration. Pregnancy rates were 62.5%, 79.2%, 75% and 62.5% in VL, L, S and VS groups, respectively. Abortion rates were 13.3%, 5.3%, 5.6% and 13.3%, also kidding rates were found to be 86.6%, 94.7%, 94.4% and 86.6% in VL, L, S and VS groups, respectively. Fertility rates were 54.2%, 75%, 70.8% and 54.2% in VL, L, S and VS groups, respectively. No significant difference was observed in pregnancy rates, abortion and kidding rates among the groups (p>0.05). As a result, CIDR has a wide range of application period in TAI protocols in Damascus goats during the breeding season. The short-term usage as short as 3 days, will offer high flexibility in TAI protocols of goats. Even no statistical difference was obtained among the groups, lower rates of fertility in VS and VL groups may provide economic loss. Further studies with a larger number of animals are needed to clarify the questions about fertility and economic issues.Öğe The Effect of Gonadotropin Releasing Hormone Administration on Fertility and Embryonic Loss in Goats during the Anoestrus Period(Universidade Federal do Rio Grande do Sul, 2021) Köse, Ayşe Merve; Ürer, Ece Koldaş; Sarıbay, Mustafa Kemal; Doğruer, Gökhan; Karaca, Fikret; Çetin, Nurdan Çoskun; Demirezer, HaydarBackground: Following the induction of oestrus out of season in small ruminants, low fertility and variations in fertility rates are associated with embryonic losses. One of the main causes of embryonic loss is luteal dysfunction. Gonadotropin Releasing Hormone (GnRH) supports the luteal structure, and increasing progesterone levels may be beneficial in terms of promoting embryonic life. The main objective of the present study was to evaluate the efficacy of GnRH administration following an oestrus induction protocol in the anoestrus season for preventing embryonic loss in goats having failure to conceive during the season. Materials, Methods & Results: In the study, 106 Damascus goats aged 3-5 years and weighing 45-60 kg were used. The oestrus of 106 goats in the anoestrous group was stimulated with progesterone and pregnant mare serum gonadotropin (PMSG) treatment. Out of breeding season, goats were divided into the 4 following groups: GnRH0 (n = 27), GnRH7 (n = 26), GnRH0+7 (n = 27) and control (n = 26). In each goat, an intravaginal sponge (IS) containing 20 mg of fluorogestone acetate (FGA) was placed into the vagina and left for 9 days. With the withdrawal of the sponge, 550IU PMSG and 125 ?g of d-cloprostenol were injected intramuscularly. Oestrus detection was made via teaser bucks for 3 days starting 24 h after withdrawal of the IS. Eighteen bucks known to be fertile were used for breeding. Goats in the oestrus period were mated via natural breeding. The GnRH analogue lecirelin was injected intramuscularly at breeding in the GnRH0 group, on day 7 post-breeding in the GnRH7 group, and both at breeding and on day 7 post-breeding in the GnRH0+7 group. No injections were given to the control group. Blood samples for progesterone measurement were taken by jugular vena puncturing on days 3, 6, 7, 10, 13, 16, and 19 after breeding from 10 randomly chosen goats in all groups. The goats with a level of > 3.5 ng/mL of progesterone on day 21 post-breeding were evaluated as pregnant. Pregnancy was also viewed on day 50 after breeding by real-time ultrasonography (USG) with a 5-7.5 MHz convex probe. The oestrus rate was 96.23% (102/106) in the goats. The rates of onset of oestrus between 36-48 h, 48-60 h and 60 h and beyond were 38.7% (41/106), 21.7% (23/106) and 35.8% (38/106), respectively. The total pregnancy rate was 35.8% (38/106). There were no statistically significant differences (P > 0.05) found for the pregnancy rate, embryonic death rate or progesterone concentration of the groups. However, serum progesterone levels were statistically different in the GnRH7 group compared with the control group (P < 0.05). Discussion: After synchronisation, various anti-luteolytic strategies can be used to support corpus luteum development and elevate progesterone concentration in the luteal phase to decrease embryonic loss and increase reproductive performance. Therefore, application of GnRH to support the luteal structure and to increase progesterone levels may be beneficial in terms of supporting embryonic life. The results showed that GnRH treatment on the day 7 post-breeding following oestrus induction, including FGA and PMSG, can increase serum progesterone levels in Damascus goats in the anoestrus period. However, following oestrus induction in the anoestrus period, it was seen that GnRH treatment at breeding or on day 7 after breeding did not have any positive effect on embryonic loss or reproductive performance. In conclusion, it was considered that this protocol could be implemented successfully, yielding a 35% pregnancy rate in Damascus goats in the anoestrus period, but embryonic loss must be deeply studied in detail. © 2021 Universidade Federal do Rio Grande do Sul. All rights reserved.Öğe The Effect of Selenium, Vitamin E, Vitamin A and Vitamin D3 Applications on Fertility in Awassi Sheep with Estrus Synchronization During the Breeding Season(2023) Efe, Mehmet; Sarıbay, Mustafa Kemal; Ürer, Ece Koldaş; Köse, Ayşe MerveThe purpose of this study was to determine the effects of selenium, vitamin E, vitamin A, and vitamin D3 treatments on reproductive parameters in Awassi sheep fed solely dry grass and grain stubble duringthe breeding season with estrus synchronization. Seventy-five sheep were implanted with intravaginal sponges containing 20 mg of flugestone acetate for 9 days for estrus synchronization. On the day the sponges were inserted, the first group received an intramuscular injection of a supplement containing 200,000 IU of vitamin A, 30,000 IU of vitamin D3, and 20 mg of vitamin E, as well as a supplement containing 1 mg of sodium selenite and 60 mg of vitamin E. The second group was the control group, with no supplementary vitamin injected. On the day of sponge removal, the sheep received intramuscular injections of 500 IU PM SG and 250 mcgcloprostenol sodium in both groups. The sheep in the first group were given a second injection of the supplement on the same day that contained 20 mg of vitamin E, 30,000 IU of vitamin D3, and 200,000 IU of vitamin A. The sheep that showed signs of estrus were mated naturally after the estrus synchronization. Estrus rates were 86.11% and 85.29%, conception rates were 74.19% and 58.62%, pregnancy rates were 63.88% and 50%, lambing rates were 100% and 100%, and litter size was found to be 126.08% and 123.52% in Group I and II, respectively (P=0.858). Although there was no significant difference in the reproductive characteristics between the groups (P>0.05),Group I had a greater pregnancy rate and litter size. During the breeding season, it is believed that the regular application of vitamin and mineral supplements on a program basis in sheep fed only dry pasture and grain stubble contributed tofertility.Öğe Effects of selenium, vitamin E, and ?-carotene administration on fertility of Awassi ewes synchronized for estrus in non-breeding season(2022) Özar, Enver; Sarıbay, Mustafa Kemal; Köse, Ayşe Merve; Sertkol, RamazanThe aim of this study was to evaluate the effect of selenium, ?-carotene, and vitamin E administration on fertility of Awassi ewes synchronized in non-breeding season. A total of 80 multiparous Awassi ewes, aged 2 to 6 years were enrolled in the study. Intravaginal sponges containing flugeston acetate (20 mg cronolon) was inserted into vagina and allowed to remain in vagina for nine days. Ewes were randomly divided into two groups. Group I received intramuscular injections of 1 mg sodium selenite, 60 mg vitamin E, 75 mg ?-carotene, and 100 mg DL-?-tocopherol acetate at sponge insertion, sponge removal, and 18 days after the introduction of ram. Group II remained as control group and received no treatment. On the removal of the sponges, 500 IU eCG and 0.075 mg D-cloprostenol were injected intramuscularly. Ram was introduced for 1 hr twice a day 24 hours after the sponge removal. Interval between sponge removal and estrus, estrus rates, conception rates, pregnancy rates, lambing rates, and fecundity rates in group I and group II were 45.30±1.71 and 43.94±1.72 hours, 79.1% and 86.6%, 66.66% and 72.41%, 54.05% and 58.33%, 100% and 100%, and 135% and 138%, respectively. There were no statistical differences between the groups (p>0.05). In conclusion, the administration of Se, ?-carotene, and vitamin E in estrus synchronization protocols in non-breeding season had no positive effect on the fertility characteristics of Awassi sheep.Öğe The effects of supplemental niacin and methionine on serum glucose, betahydroxybutyric acid, and non-esterified fatty acid levels during late gestation and early postpartum period in Damascus dairy goats(TÜBİTAK, 2020) Sarıbay, Mustafa Kemal; Köse, Ayşe Merve; Özsoy, Bülent; Ahsan, Umair; Koldaş Ürer, Ece; Köse, Serkan İrfan; Doğruer, GökhanThe objective of this study was to assess the changes in serum glucose, beta-hydroxybutyric acid (β-HBA), and nonesterified fatty acid (NEFA) levels in Damascus dairy goats fed niacin (Nia) and methionine (Met) during late gestation and early postpartum period. A total of 75 dairy goats at 105th day of gestation were divided into 3 groups as control (no supplementation), Nia (20 g/kg Nia), and Met (2.5 g/kg Met) groups. The dietary treatments continued until parturition. Dairy goats fed dietary Nia had greater serum glucose levels on day 125 of gestation compared to the other dietary treatments (P < 0.05). On day 135 of pregnancy, serum glucose levels were higher in Met group than control group (P < 0.05). Serum β-HBA levels decreased on days 135 and 145 in dairy goats fed Nia than those in control group. Dietary Nia and Met lowered serum β-HBA levels on day 10 postpartum compared to control group (P < 0.05). Serum NEFA levels decreased (P < 0.05) on days 135 and 145 in dairy goats fed Nia supplemented ration than those in control group. Serum NEFA levels d 10 postpartum were different among the groups (P < 0.05). In conclusion, dietary Nia and Met supplementation improved serum glucose levels on day 125 of gestation while decreasing β-HBA and NEFA levels during late gestation and early postpartum period in Damascus dairy goats under the conditions of present study.Öğe Embryo Transfer in Fleckvieh Simmental Cows: A Preliminary Study(Unique Scientific Publishers, 2022) Köse, Ayşe Merve; Çizmeci, Sakine Ülküm; Dinç, Dursun AliThis study was aimed at investigating pregnancy rates achieved with multiple ovulation and embryo transfer in Simmental cows, which are characterized by a high milk yield. For this purpose, eight cows were used as donors and for each donor, recipient groups of 10 animals, including both heifers and cows, were established. Recipients were synchronized by two intramuscular injections of prostaglandin F2? 11 days apart. The treatment of the donors consisted of the intravaginal placing of a CIDR on day 0, the application of 400mg FSH in decreasing doses, starting on day four, the administration of prostaglandin F2? and the removal of CIDR on day 8. The donors were inseminated twice on day 9 and once on day 10. Uterine flushing was performed, trans-cervically, on day 7 after insemination. The ovulation rate was determined as 12.25±1.42. Sixteen transferable embryos (2.0±3.23, 88.9%) were collected. The 12 embryos of Grade 1 quality and the 4 embryos of Grade 2 quality were transferred by transcervical route to 12 heifers and 4 cows, respectively. The pregnancy rates achieved in the heifers and cows were 50% and 25%, respectively (P>0.05). As a result, the MOET scheme applied in Fleckvieh Simmental Cows produced satisfactory superovulatory responses and resulted in the collection of quality embryos. The embryo recovery rate was poor but, overall, the ovulation rate, the quality of the collected embryos and the pregnancy rates achieved under field conditions in this preliminary study were considered to be satisfactory. © 2022, Unique Scientific Publishers. All rights reserved.Öğe In vitro culture of in vivo Saanen goat embryos by vitrification(2016) Köse, Ayşe Merve; Tekeli, TevfikThe purpose of this study was to investigate the survival rate of high-quality embryos (n: 101) derived in vivo from Saanen goats (n: 15) in culture following their vitrified freezing and thawing during the breeding season. The in vitro postthaw survival rates of 101 vitrified embryos at 24, 48, and 72 h were 59.4%, 33.6%, and 25.7%, respectively. According to the developmental stage of the embryos, the survival rates were 51.3%, 20.5%, and 15.4% in the morula, and 64.5%, 41.9%, and 32.3% in the blastocyst, respectively. The survival rates of the blastocysts and morulae at 48 and 72 h were significantly different (P < 0.05). While the survival rates of the embryos of Grade 1 quality at 24, 48, and 72 h were 78.6%, 46.4%, and 32.1%, Grade 2 quality survival rates were 35.5%, 17.8%, and 17.8%, respectively. The survival rates of Grades 1 and 2 embryos at 24 h (P < 0.001) and 48 h (P < 0.05) were significantly different. As a result, it was concluded that the embryos to be frozen should be selected according to their development stage and quality, and preferably should be of Grade 1 quality in the blastocyst stage for the cryopreservation of in vivo-derived goat embryos by vitrification.Öğe Investigation of the effect of a progesterone free superovulation protocol on embryo yield and quality in goats(Mehria Publishers, 2017) Çizmeci, Sakine Ülküm; Köse, Ayşe Merve; Güler, Mehmet; Tekeli, TevfikThe main objective of the present study is to determine the effects of progesterone and progesterone-free superovulation protocols on embryo count and quality in goats. The animal material of the study is consisted of 1-3-year-old 22 goats and 3 bucks. During the breeding season, the goats were divided into two groups of 11, and superovulation was applied. In the control group, goats were synchronized with intravaginal sponges containing 20 mg of fluorogestone acetate for 12 days. Four days after oestrus in the experimental group and on the 9th day after sponge application in control group decreasing doses of FSH (Follicle stimulating hormone) (50; 30; 20 mg) were injected intramuscularly at 12 hour intervals. The sponge was removed on the 12th day in the control group. In both groups, oestrus was observed 24 hours after the fifth dose of FSH and the uterus flushing was performed on the 7th day after mating. In the study, superovulation response was obtained 100% in control group and 25% in experimental group. The recovery rate and transferable embryos were determined 61.5; 82.81 and 23.3%; 71.43% respectively and there was no difference between the groups (P > 0.05). In the non-progesterone-applied group of animals, it was observed that the cycle cannot be fully dominated, sufficient progesterone level could not be reached and gonadotropin application was, therefore, insufficient. Although progesterone administration is thought to have a negative effect on embryo quality, applying a superovulation by using progesterone has been shown to be more successful on superovulation and embryo collection rates. © 2017 IJVS.Öğe Investigation of the effectiveness of ultrasonography in determining pregnancy and the number of fetuses on the 35th day of pregnancy in Awassi sheep(2022) Tekin, Tufan Can; Köse, Ayşe MerveIn this study, it was aimed to determine the effectiveness of transabdominal ultrasonographic imaging on the 35th day of pregnancy in determining the pregnancy status and number of fetuses in sheep. 69 Awassi sheep were used in the study. Sheep were mated after oestrus synchronization during the breeding season. On the 35th and 50th days after mating, a pregnancy examination was performed twice transabdominally in each animal by ultrasonography. Sheep with single/multiple offspring were noted according to examination performing on day 35 and lambing record. According to ultrasonography results, early foetal death rate was determined as 6.1%. Sensitivity, specificity, positive predictive value, negative predictive value ratios for pregnancy examination findings and single/multiple offspring data by transabdominal ultrasonography on day 35 were determined as 91.30%, 100%, 100%, 83.3% and 38.46%, 81.25%, 76.92%, 44.82%, respectively. While the consistency of transabdominal ultrasonographic imaging for pregnancy on day 35 and 50 were high agreement (Kappa=0.864, p<0,001), consistency of single/multiple pregnancy findings on day 35 and at birth were low (Kappa=0,170, p>0.05). The rates of transabdominal ultrasonographic examination on day 35 for correct diagnosis of pregnancy status and the number of fetuses were found as 93.93% and 54.76%, respectively. Finally, it can be concluded that transabdominal ultrasonographic examination on day 35 for early pregnancy diagnose in sheep is highly effective in determination of pregnant sheep, and recurrent examination on days 35 and 50 may be useful for detecting of early foetal deaths. In order to determine the number of fetuses, repeated examinations should be performed in the following days of pregnancy.Öğe Mustafa Kemal Üniversitesi, Veteriner Fakültesi Doğum ve Jinekoloji Kliniği'ne 2010-2015 yılları arasında getirilen hayvanların genel analizi(2016) Sarıbay, Mustafa Kemal; Doğruer, Gökhan; Ergün, Yaşar; Köse, Ayşe Merve; Koldaş, EceAmaç: Bu çalışmada 2010-2015 yılları arasında Mustafa Kemal Üniversitesi, Veteriner Fakültesi, Doğum ve Jinekoloji Kliniğine getirilen hayvan türleri ve kliniğine getirilme ne-denlerinin genel bir analizinin yapılması amaçlandı. Gereç ve Yöntem: Çalışmada kliniğine başvuran hayvan sa-yıları ve başvuru nedenleri klinik muayene defter kayıtları incelenerek tespit edildi ve türlere göre gruplandırıldı. Bulgular: Kliniğe getirilen toplam hayvan sayıları 2010-2015 yılları arasında sırasıyla 168, 156, 110, 135, 111 ve 148 olarak tespit edildi. Kliniğe getirilen toplam 828 hayvanın türlere göre dağılımı, sığır (inek+düve) %44.08, köpek %20.04, koyun %16.18, keçi %13.52 ve kedi %6.15 olarak belir-lendi. Hayvanların başlıca kliniğe getiriliş sebeplerini, sığır-larda gebelik muayenesi ve genital organ muayenesi; koyun ve keçilerde gebelik muayenesi ve güç doğum; köpek ve ke-dilerde ise gebelik muayenesi ve ovariohisterektomi olguları oluşturdu. Kliniğe getirilen hayvan sayısında yıllara göre de-ğişimin olmadığı fakat getirilen hayvan türlerinin sayılarının birbirine yakın olduğu ve tüm hayvan türlerinde kliniğe ge-tiriliş sebebinin en çok gebelik muayenesi olduğu belirlendi. Öneri: Elde edilen verilerin öğrencilerin veteriner fakültesi tercihi yaparken ön bilgi edinmelerine katkı sağlayabileceği ve bölgede çalışan ya da çalışmayı düşünen veteriner hekim-lere ve araştırmacılara bu alanda yardımcı olabileceği kana-atine varıldı.Öğe Saanen ırkı keçilerde gebelik sırasında serum oksidatif durum ve biyokimyasal parametre düzeyleri(2015) Aydın, İbrahim; Köse, Ayşe MerveSaanen ırkı keçilerde gebelik sırasında serum oksidatif durum ve biyokimyasal parametre düzeyleri. Amaç: Bu çalışmada Saanen keçilerinde gebelik sırasında serum oksidatif durum ve biyokimyasal parametrelerdeki değişimlerin belirlenmesi amaçlandı. Gereç ve Yöntem: Çalışmada 15 adet Saanen ırkı keçiden gebelik öncesi, gebeliğin 1., 2., 3., 4., 5. ayları ve doğum sonrasında kan örnekleri alındı. Serum malondialdehid ile antioksidan aktivite düzeyleri ELISA okuyucusunda, biyokimyasal parametreler ise otoanalizörde ölçüldü. Bulgular: Malondialdehid konsantrasyonları gebelik süresince ve doğumdan sonra önemli derecede düştü ve gebeli- ğin 3. ayında en düşük düzeyde belirlendi (P<0.05). Antioksidan aktivite konsantrasyonları gebelik süresince kademeli olarak arttı ve gebeliğin 3. ayında en yüksek değere ulaştı (P<0.05). Serum karaciğer hasar parametrelerinde dalgalı bir seyir belirlendi. Serum alanin aminotransferaz ile aspartat aminotransferaz düzeyleri 3 ile 5. aylarda, gama glutamil transferaz düzeyleri ise 1. ayda yüksek olarak belirlendi (P<0.05). Kan üre nitrojen düzeyi ise 5. ayda yüksek olarak belirlendi (P<0.05). Öneri: Keçilerde gebelik sırasında oksidatif stres oluştuğu, ancak yeterli düzeyde beslenen keçilerde antioksidan kapasitenin lipid peroksidasyon oluşumunu engelleyebildiği ifade edilebilir.Öğe Unilateral uterine torsion in a pregnant bitch(Selçuk Üniversitesi Veteriner Fakültesi, 2018) Doğruer, Gökhan; Köse, Ayşe Merve; Koldaş Ürer, Ece; Doğruer, AzimeThis report describes the diagnosis and treatment of a case of unilateral uterine torsion, which was detected at the caesarean section of a pregnant bitch. A one-year-old, 34 kg half-breed Kangal dog, with signs of apathy, anorexia and emesis for the past two days was the material of this case report. The dog only displayed a mild apathy. Mucous membranes colour, capillary refilling time, heart and respiratory rates were within the physiological ranges. The body temperature was 37.5°C. A mucoid brown-greenish coloured vaginal discharge was determined. The measured biochemical values fell within the physiological ranges. Both live and dead foetuses were determined ultrasonographically then the number of dead foetuses increased half an hour later on second ultrasonographic examination so it was decided to perform a caesarean section. One female and two male live foetuses from the right uterine horn and two dead female foetuses from the left uterine horn were removed. The left uterine horn displayed hyperaemia, haemorrhage and fragility with a 1800° torsion along its long axis, near the uterine bifurcation. The amniotic fluids appeared normal, the chorioallantoic fluid was haemorrhagic in the left horn. Total ovariohysterectomy was performed. The uterine torsion cases may be manifested with nonspecific clinical signs such as anorexia and emesis. In the event of increased number of dead foetuses in repeated ultrasonographic examination, the presence of uterine torsion should be considered. In such cases, the pregnant animal can be saved by surgical intervention, as was in this case study.Öğe Üreme Mevsimi Girişinde Doğum Yapmış Laktasyondaki Koyunların Aynı Üreme Mevsimi İçinde Östrüs Senkronizasyonunda Kısıtlı Emzirme ve eCG Kullanımın Fertilite Üzerine Etkisi(2024) Kutlu, Metehan; Köse, Ayşe Merve; Ürer, Ece KoldaşSunulan çalışmada, üreme mevsimi içerisinde kısa süreli progestajen uygulamaları ile östrüsları senkronize edilen laktasyondaki Macar Merinos ırkı koyunlarda kısıtlı emme ve eCG’nin farklı dozlarının östrüs uyarımı ve fertilite üzerine etkilerinin araştırılması amaçlandı. Östrüs uyarımı başlangıcında koyunlar rastgele 4 gruba ayrıldı. Bu koyunlara 0. gün intravajinal 60 mg medroksiprogesteron asetat içeren sünger uygulandı, süngerler 7 gün süreyle vajinada tutuldu. Sünger uygulama süresi içerisinde, laktasyon gruplarındaki koyunlar (L) kuzuları ile günde 5 saat emmeleri için beraber kalırlarken, kısıtlama gruplarındaki koyunlar (K) kuzuları ile 2 günde bir 1 saat beraber bırakıldı. Tüm koyunlarda uygulamanın yedinci günü süngerler çıkarıldı ve sünger çıkarılması anında 250 ?g kloprostenol sodyum ile 350 IU dozda (L-350 ve K-350 gruplarına) ve 550 IU dozda (L-550 ve K-550 gruplarına) eCG uygulandı. Östrüs tespiti süngerlerin çıkartılmasından 12 saat sonra başlanarak sabah ve akşam gerçekleştirildi. Östrüste olduğu tespit edilen koyunlar elde aşım yöntemi ile çiftleştirildi. Hayvanlara aşımdan sonraki 48. günde ultrasonografik gebelik muayenesi yapıldı. Gruplarda ilk aşımda, ikici aşımda ve toplam aşımlarda, östrüs oranı, gebelik oranı, kuzulama oranı ve yavru verimi parametreleri hesaplandı. Yapılan istatistiksel analizlere göre gruplar arasında fark belirlenemedi (P>0.05). Sonuç olarak üreme mevsimi girişinde doğum yapan laktasyondaki Macar Merinos ırkı koyunların aynı üreme mevsimi içerisinde kısa süreli progestajen uygulamaları ile yeniden gebe bırakılmasında kısıtlı emme ve eCG’nin farklı dozlarının fertilite parametrelerini etkilemediği ancak östrüslerin yeniden toplulaştırılabileceği ve kuzu veriminin sayısal olarak artırılabileceği kanısına varıldı.
