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Öğe Association of childhood obesity with retinal microvasculature and corneal endothelial cell morphology(Walter De Gruyter Gmbh, 2021) Kurtul, Bengi Ece; Cakmak, Ayse Idil; Elbeyli, Ahmet; Karaaslan, Abdulkerim; El, CigdemObjectives: To investigate the optical coherence tomography angiography (OCTA) and specular microscopy (SM) findings in obese children and compare them with healthy ones. Methods: In this prospective study, 50 eyes of 25 obese children [body mass index (BMI) >= 95th percentile], 36 eyes of 18 control age- and sex- matched healthy subjects (BMI <85th percentile) were included. Demographic features and ophthalmological examination including OCTA measurements as well as SM findings were assessed. Cellular morphology was observed by noncontact SM and results for corneal endothelial cell density (cells/mm(2)), coefficient of variation of cell size and percentage of hexagonal cells were obtained. The OCTA was performed with 6 x 6 mm sections for macula and 4.5 x 4.5 mm sections for optic disc in all eyes. Foveal retinal thickness (FRT), retinal nerve fiber layer (RNFL) thickness, vessel density in different sections of retina and optic nerve head were analyzed. Results: All SM parameters, RNFL thickness for average, and all quadrants and optic disc radial peripapillary capillary densities were similar between groups. However, FRT, flow area for choriocapillaris, superficial and deep foveal capillary densities were significantly higher in obese group when compared to controls (242.4 +/- 18.2 mu m vs. 232.1 +/- 16.5 mu m, p=0.024, 2.2 +/- 0.1 mm(2) vs, 2.2 +/- 0.0 mm(2), p=0.042, 22.4 +/- 6.9% vs. 15.6 +/- 5.5%, p=0.001, and 38.9 +/- 7.5% vs. 31.1 +/- 8.6 %, p=0.001, respectively). Conclusions: Obese children seem to have higher values of FRT, flow area for choriocapillaris, superficial and deep foveal capillary densities. These results may have significant implications for understanding of how childhood obesity could affect retinal microvasculature.Öğe Bilateral double-headed recurrent pterygium: A case presentation and literature review(International Virtual Ophthalmic Research Center, 2020) Kurtul, Bengi Ece; Kakac, Ahmet; Karaaslan, AbdulkerimPterygium is a frequent corneal disease characterized by growing of fibrovascular tissue from the bulbar conjunctiva onto the cornea. Although the causes of pterygium are not obvious, sun exposure is closely correlated with its development. Pterygium, especially double-headed pterygium is mostly seen in warm climate and in individuals who work outdoors. A minority of pterygium is double-headed (both temporal and nasal origins). Bilateral recurrent double-headed pterygium is a very rare condition. Here, we reported a 35-year-old male patient with bilateral recurrent double-headed pterygium. A brief review about the recent literature concerning the etiology, associated risk factors, operation types and management of patients with recurrent pterygium was also discussed. The patient was a field worker, smoker and had a family history of pterygium. There was no ocular surgery history except pterygium surgery 15 years ago in both eyes. A successful pterygium excision was performed under local anesthesia with the vertical split conjunctival autograft transplantation (CAT) in both temporal and nasal parts of the right eye (randomly) for cosmetic disfigurement and avoidance of recurrence. The pathological report was consistent with pterygium. At postoperative first week, first and 1.5th month visits, conjunctival autografts were in place and stable. No complications such as infection, corneal thinning or graft dislocation were seen. The patient was satisfied with his right eye and demanded the same surgery for his left eye. We suggest vertical split simultaneous CAT as a safe and useful surgical method for the treatment of recurrent double-headed pterygium; however, longer follow-up is required to confirm the outcome. © 2020, Author(s).Öğe Investigation of the optic disc and retinal microvasculature by optical coherence tomography angiography in children with asthma(Wolters Kluwer Medknow Publications, 2023) Karaaslan, Abdulkerim; Kurtul, Bengi Ece; Cakmak, Ayse Idil; El, CigdemPURPOSE: To assess the optic disc and retinal microvasculature by optical coherence tomography angiography (OCTA) in asthmatic children. MATERIALS AND METHODS: Thirty asthmatic children (asthma group) and 30 control age- and sex-matched healthy controls (control group) were included in this cross-sectional study. The asthma group was then divided into two subgroups according to the presence of inhaled steroid use. Demographic findings were noted. Retinal nerve fiber layer (RNFL) thickness and vessel density in different sections of the retina and optic nerve head were analyzed by OCTA. RESULTS: RNFL thickness for temporal quadrants and flow area for outer retina levels were significantly lower in the asthma group than the control group (72.58 +/- 10.99 mu m vs 77.73 +/- 9.73 mu m, P = 0.015, and 0.60 +/- 0.31mm(2 vs.) 0.72 +/- 0.31mm(2), P = 0.047, respectively). However, inside disc vascular densities were significantly higher in the asthma group when compared to controls (55.16% +/- 3.71% vs. 52.08% +/- 3.79%, P < 0.001). Inside disc vascular densities were also significantly higher, and RNFL thickness for temporal quadrants was significantly lower in the asthmatic patients without steroid use subgroup when compared to others (P < 0.001, P = 0.012, respectively). CONCLUSION: Lower values of temporal quadrant RNFL, and flow area for outer retina, but higher levels of inside disc vascular density seem to be associated with asthmatic children. OCTA findings in asthmatic children appear to be regardless of inhaled steroid use.Öğe Schnyder Corneal Dystrophy: A Rare Case Report(Nepal Ophthalmic Soc, 2020) Kurtul, Bengi Ece; Elbeyli, Ahmet; Ozcan, Deniz Ozarslan; Ozcan, Sait Coskun; Karaaslan, AbdulkerimIntroduction: Schnyder corneal dystrophy (SCD) is a rare, autosomal dominant, anterior stromal dystrophy described as progressive bilateral corneal opacification due to abnormal accumulation of cholesterol and phospholipids in the cornea. The clinical signs can change as the patient ages. SCD with different presentations may actually be misdiagnosed. Early diagnosis would help to rule out other potentially sight threatening or treatable conditions like infectious keratitis or drug toxicity. Case: We present a case of a 34-year-old Syrian male patient, came to our clinic for bilateral decreased visual acuity for 5 years. His visual acuity was 0.15 in both eyes. Slitlamp examination revealed corneal arcus or disk-like lesion and polychromatic crystalline depositions in both eyes in subepithelial and the anterior 1/3 of the stroma. The mild onset of arcus lipoides was also seen. Central corneal thickness results were 507 mu m in the right eye and 503 mu m in the left eye. A diagnosis of Schnyder corneal dystrophy was thought based on clinical presentation and coexistence dyslipidemia of the patient. Conclusion: Ophthalmologists should keep in mind SCD and its associated systemic findings that need to be evaluated and managed properly.
