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Öğe Adenosine deaminase and biochemical liver function tests in the dermatophytic cattle(Natl Veterinary Research Inst, 2006) Atakisi, Emine; Karapehlivan, Mahmut; Atakisl, Onur; Kontas, Tunay; Marasli, SabanAdenosine deaminase (ADA) activity and liver function tests were examined in dermatophytic cattle. In addition, the possible effect/s of the disease oil the activities of liver enzymes were investigated. Tell dermatophytic and 10 healthy animals aged between 10 and 12 months were used. Blood samples were obtained from each animal. The samples were left for 30 min at room temperature, and then centrifuged at 3000 x g for 10 min. Serum ADA, lactate dehydrogenase (LDH), alanine aminotransferase (ALT), aspartate aminotransferase (AST). gammaglutamyl transferase (GGT) Were analysed colorimetrically. Serum ADA, LDH, and ALT activities were significantly higher in dermatophytic cattle, compared to those of healthy group (P < 0.01). ill addition. GGT and AST activities ill dermatophytic cattle were statistically compared higher to those of the healthy ones. Ill conclusion, the results of the present Study show that the increases in ADA and liver enzyme activities call be in indication of the loss of liver function. The increase in enzyme activity in the current study might have been caused by metabolic products of the Fungi.Öğe Is CAPE a Therapeutic Agent for Wound Healing?(Medwell Online, 2009) Kontas-Askar, Tuenay; Altug, M. Enes; Karapehlivan, Mahmut; Atakisi, Emine; Hismiogullari, Adnan AdilWound healing involves a number of processes, including an acute inflammatory response to production of Reactive Oxygen Species (ROS) and depression in antioxidant status. The aim of the study is to examine the therapeutic effects of Caffeic Acid Phenethyl Ester (CAPE), an antioxidant agent, on cutaneous wound healing in a rat model. There was a significant decrease in serum, wound and liver tissue TSA and serum LBSA levels in the CAPE group than in the control group. Also there was a significant decrease in serum and wound tissue TAC levels of the control group when compared to the CAPE group. But there was no difference between the groups in serum ADA activity, PBSA levels and liver tissue TAC levels. In conclusion, the present study showed the CAPE's efficacy in the treatment of cutaneous wounds by its antioxidant and ROS-scavenging capabilities.