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Öğe Anti-proliferative Effects of Trigonella foeniculum and Eucalyptus camaldulensis on Human Melanoma Cells(Wiley, 2017) Duran, Nizami; Duran, Gulay Gulbol; Kaya, D. Alpaslan; Ay, Emrah; Tumer, Cemil; Demir, Enver Ahmet[Abstract Not Available]Öğe Comparing the effect of sub-critical water extraction with conventional extraction methods on the chemical composition of Lavandula stoechas(Elsevier Science Bv, 2008) Giray, E. Sultan; Kirici, Saliha; Kaya, D. Alpaslan; Turk, Murat; Sonmez, Ozgur; Inan, MemetThe volatile extract composition of Lavandula stoechas flowers obtained by hydrodistillation (HD), subcrtical water extraction (SbCWE) and organic solvent extraction under ultrasonic irradiation (USE) were estimated by gas chromatography-mass spectrometry (GC-MS). One hundred and twenty four components were detected in SbCWE extracts while 94 and 65 signals were gained from HD and USE extracts, respectively. Most of the constituents were identified. The major compounds in all three extracts were fenchon, camphor, myrtenyl acetate, myrtenol and 1,8-cineol, but they differ in quantitatively. The total monoterpene hydrocarbons are higher in HD and USE extracts than those of SbCWE extract. However, SbCWE extract had higher concentration of light oxygenated compounds which contributes to the fragrance of the oil in a major extension. Heavy-oxygenated compounds was also in higher abundance in SbCWE extract (9.90%) than those of HD and USE extracts (3.19 and 4.78%, respectively). Effect of temperature on the extraction yield of SbCWE was investigated and while oil yield was increasing with an increase in temperature, a decrease in the extraction ability of sub-critical water toward the more polar compounds such as, 1,8-cineol, camphor and fenchon, was observed. Kinetic studies shown that SbCWE is clearly quicker than conventional alternatives. Most of components of volatile compounds were extracted at 15 min. (C) 2007 Elsevier B.V. All rights reserved.Öğe Effect of harvest time on essential oil composition of thymbra spicata L. growing in flora of adıyaman(American-Eurasian Network for Scientific Information, 2011) Inan, Memet; Kirpik, Muzaffer; Kaya, D. Alpaslan; Kirici, SalihaThymbra spicata L. is an aromatic shrub growing wild in different regions of Turkey. This plant has traditionally been used for different purposes by local settlements. Leaves of Thymbra spicata were collected from Kahta district of Adi{dotless}yaman (684 m, 370 43' N, 380 39' E) in three different harvest time as follows: before flowering (10 May 2010), in flowering (21 May 2010) and after flowering stage (10 June 2010). Essential oil contents of the plant samples were determined by Hydro-distillation in Clevenger Apparatus with three hours. Composition of the essential oils was determined by Gas Chromatography Mass Spectrometry (GC-MS). All the laboratory analysis was performed with three replications. In conclusion, the highest and the lowest essential oil contents of Thymbra spicata were obtained from the full blooming harvests (3,56%) and after flowering (3,38%), respectively. The lowest essential oil content was found in before flowering harvest (3,10%). Besides essential oil contents, essential oil composition of Thymbra spicata was also affected by different harvest times.Öğe Effect of Seed Powder of a Herbal Legume Fenugreek (Trigonella foenum-graceum L.) on Growth Performance, Body Components, Digestive Parts, and Blood Parameters of Broiler Chicks(Zoological Soc Pakistan, 2013) Duru, Metin; Erdogan, Zeynep; Duru, Asuman; Kucukgul, Altug; Duzguner, Vesile; Kaya, D. Alpaslan; Sahin, AhmetThe aim of this study was to investigate the effects of dietary Trigonella foenum-graceum L. seed powder (TFGSP) on growth performance, blood glucose, protein and lipid profile of broilers (Ross-308). One hundred ninety two, 1-d old mixed sex broiler chicks were allocated to 5 dietary treatments in which 0, 5, 10, 20 and 40 g TFGSP doses per kg commercial broiler diet were added for a period of 42 days. The results showed that body weight and the breast weight decreased after TFGSP treatment compared to control (P<0.05). Feed intake decreased after 5 g TFGSP treatment while 40 g TFGSP treatment decreased feed efficiency and leg weight compared to control (P<0.01). There was no significant difference in weights of digestive system parts, except duodenum weight and lipid oxidation between control and treatment groups. A 20 g TFGSP treatment enhanced blood glucose level (P<0.01), but decreased triglyceride level (P<0.01) compared to control. At 40 g TFGSP the blood cholesterol decreased (P<0.05) but LDL level increased compared to control (P<0.01). In conclusion, TFGSP addition to broiler diet decreased appetite and, consequently, reduced growth performance, more likely, attributting to the enhanced blood glucose level.Öğe The Effects of Essential Oils of Nigella sativa L. on p53 Gene Expression and Cell Apoptosis in HT-29 Colon Carcinoma Cells(Wiley, 2017) Duran, Nizami; Duran, Gulay Gulbol; Kaya, D. Alpaslan; Ay, Emrah; Demir, Enver Ahmet; Dogan, Hatice[Abstract Not Available]
